Parathyroid Hormone (PTH) Attenuation Trial in Hemodialysis-2
Public ClinicalTrials.gov record NCT05836220. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy and Safety of Dose-Titrated PLS240 in the Treatment of Secondary Hyperparathyroidism in Individuals With End Stage Kidney Disease on Hemodialysis (PATH-2) With an Open-Label Extension
Study identification
- NCT ID
- NCT05836220
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Pathalys Pharma
- Industry
- Enrollment
- 412 participants
Conditions and interventions
Interventions
- PLS240 Drug
- Placebo Drug
- Open-Label Extension PLS240 Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 14, 2023
- Primary completion
- Aug 4, 2025
- Completion
- Aug 4, 2025
- Last update posted
- Sep 8, 2025
2023 – 2025
United States locations
- U.S. sites
- 50
- U.S. states
- 20
- U.S. cities
- 46
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Site Number: USA039-2 | Anaheim | California | 92801-6731 | — |
| Site Number: USA001-2 | Chula Vista | California | 91910-3813 | — |
| Site Number: USA020-2 | Escondido | California | 92025-4402 | — |
| Site Number: USA042-2 | Fresno | California | 93720-3389 | — |
| Site Number: USA034-2 | Fullerton | California | 92832-3037 | — |
| Site Number: USA046-2 | Glendale | California | 91205-3313 | — |
| Site Number: USA019-2 | Granada Hills | California | 91344-7407 | — |
| Site Number: USA005-2 | La Mesa | California | 91942-3017 | — |
| Site Number: USA044-2 | Lancaster | California | 93534-2831 | — |
| Site Number: USA030-2 | Los Angeles | California | 90022-4302 | — |
| Site Number: USA043-2 | Los Angeles | California | 90033 | — |
| Site Number: USA022-2 | Moorpark | California | 93021-3352 | — |
| Site Number: USA049-2 | Northridge | California | 91324-2927 | — |
| Site Number: USA033-2 | Northridge | California | 91324-3528 | — |
| Site Number: USA003-2 | San Diego | California | 92111-3636 | — |
| Site Number: USA018-2 | San Dimas | California | 91773-3539 | — |
| Site Number: USA056-2 | Tarzana | California | 91356-2806 | — |
| Site Number: USA021-2 | Tarzana | California | 91356-3647 | — |
| Site Number: USA052-2 | Victorville | California | 92395-8322 | — |
| Site Number: USA023-2 | Arvada | Colorado | 80002-3714 | — |
| Site Number: USA031-2 | Aurora | Colorado | 80045-7202 | — |
| Site Number: USA017-2 | Middlebury | Connecticut | 06762-2843 | — |
| Site Number: USA015-2 | Newark | Delaware | 19713-2081 | — |
| Site Number: USA004-2 | Fort Myers | Florida | 33908-4154 | — |
| Site Number: USA002-2 | Hollywood | Florida | 33024-2776 | — |
| Site Number: USA041-2 | Orlando | Florida | 32801 | — |
| Site Number: USA035-2 | South Miami | Florida | 33143-5522 | — |
| Site Number: USA013-2 | Columbus | Georgia | 31904-3603 | — |
| Site Number: USA028-2 | Mishawaka | Indiana | 46545-3519 | — |
| Site Number: USA024-2 | Wichita | Kansas | 67214-2944 | — |
| Site Number: USA054-2 | New Orleans | Louisiana | 70112 | — |
| Site Number: USA048-2 | Detroit | Michigan | 48236-2169 | — |
| Site Number: USA025-2 | Kalamazoo | Michigan | 49007-3889 | — |
| Site Number: USA016-2 | Minneapolis | Minnesota | 55404-1212 | — |
| Site Number: USA007-2 | Amherst | New York | 14228-2792 | — |
| Site Number: USA053-2 | Charlotte | North Carolina | 28208-3876 | — |
| Site Number: USA026-2 | Durham | North Carolina | 27704-2147 | — |
| Site Number: USA009-2 | Toledo | Ohio | 43606-1171 | — |
| Site Number: USA045-2 | Roseburg | Oregon | 97471-6214 | — |
| Site Number: USA010-2 | Greenville | South Carolina | 29605-4019 | — |
| Site Number: USA027-2 | Knoxville | Tennessee | 37923-3624 | — |
| Site Number: USA011-2 | El Paso | Texas | 79925-4828 | — |
| Site Number: USA029-2 | Live Oak | Texas | 78233-4767 | — |
| Site Number: USA055-2 | Prosper | Texas | 75078-1411 | — |
| Site Number: USA012-2 | San Antonio | Texas | 78221-3019 | — |
| Site Number: USA008-2 | San Antonio | Texas | 78251-4125 | — |
| Site Number: USA006-2 | Waxahachie | Texas | 75165-1399 | — |
| Site Number: USA038-2 | St. George | Utah | 84790-5898 | — |
| Site Number: USA051-2 | Fairfax | Virginia | 22033-1907 | — |
| Site Number: USA037-2 | Norfolk | Virginia | 23507-1901 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 18 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05836220, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 8, 2025 · Synced Jul 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05836220 live on ClinicalTrials.gov.