The Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

ClinicalTrials.gov ID: NCT05836987

Public ClinicalTrials.gov record NCT05836987. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

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ClinicalTrials.gov public records Last synced May 20, 2026, 7:27 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

REACT-AF: Rhythm Evaluation for AntiCoagulaTion With Continuous Monitoring of Atrial Fibrillation

Study identification

NCT ID: NCT05836987
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 3
Lead sponsor: Johns Hopkins University; Other
Enrollment: 5,350 participants

Conditions and interventions

Conditions

Atrial Fibrillation

Interventions

AFSW Guided DOAC Device
Continuous DOAC therapy Drug

Device · Drug

Eligibility (public fields only)

Age range: 22 Years to 85 Years
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: Jul 12, 2023
Primary completion: Jul 30, 2029
Completion: Jul 30, 2029
Last update posted: Apr 8, 2026

2023 – 2029

United States locations

U.S. sites: 93
U.S. states: 29
U.S. cities: 71

Facility	City	State	ZIP	Site status
Banner University	Phoenix	Arizona	85006	Recruiting
University of Southern California - Keck School of Medicine	Los Angeles	California	90033	Recruiting
University of California Los Angeles (UCLA Health)	Los Angeles	California	90095	Recruiting
UC Davis Health	Sacramento	California	95817	Recruiting
Scripps Health	San Diego	California	92103	Recruiting
Kaiser Permanente	San Francisco	California	94115	Not yet recruiting
Stanford University	Stanford	California	94305	Recruiting
University of Colorado	Aurora	Colorado	80045	Recruiting
South Denver Cardiology Associates, P.C.	Littleton	Colorado	80120	Recruiting
St. Elizabeth's Medical Center	Washington D.C.	District of Columbia	20032	Recruiting
Medical Faculty Associates George Washington University	Washington D.C.	District of Columbia	20037	Withdrawn
BayCare Health Systems	Clearwater	Florida	33759	Recruiting
University of Florida	Gainesville	Florida	32611	Recruiting
Mayo Clinic	Jacksonville	Florida	32224	Recruiting
University of Miami - Leonard S. Miller SOM	Miami	Florida	33136	Recruiting
Sarasota Memorial Health Care System	Sarasota	Florida	34236	Recruiting
Cleveland Clinic Florida	Stuart	Florida	34994	Withdrawn
Baycare Health Systems Clearwater	Winter Haven	Florida	33881	Recruiting
Emory University	Atlanta	Georgia	30332	Recruiting
Georgia Arrhythmia Consultants and Research Institute	Warner Robins	Georgia	31093	Recruiting
University of Illinois Chicago	Chicago	Illinois	60607	Recruiting
Northwestern University	Chicago	Illinois	60611	Recruiting
Rush University Medical Center	Chicago	Illinois	60612	Recruiting
University of Chicago	Chicago	Illinois	60637	Recruiting
Loyola University Chicago	Chicago	Illinois	60660	Recruiting
Alexian Brothers Health System	Elk Grove Village	Illinois	60007	Recruiting
NorthShore University HealthSystem	Evanston	Illinois	60201	Recruiting
Midwest Cardiovascular Institute	Naperville	Illinois	60540	Recruiting
Ascension St. Vincent	Indianapolis	Indiana	46260	Recruiting
University of Iowa Hospitals and Clinics	Iowa City	Iowa	52242	Recruiting
Maine Medical Partners MaineHealth Cardiology	Scarborough	Maine	04074	Recruiting
Johns Hopkins Univeristy	Baltimore	Maryland	21218	Recruiting
Tufts Medical Center	Boston	Massachusetts	02111	Recruiting
Mass General Hospital	Boston	Massachusetts	02114	Not yet recruiting
Brigham and Women's Hospital	Boston	Massachusetts	02115	Recruiting
Boston Medical Center	Boston	Massachusetts	02118	Recruiting
BMC - Brighton	Boston	Massachusetts	02135	Recruiting
Beth Israel Deaconess Medical Center	Boston	Massachusetts	02215	Recruiting
Lahey Hospital & Medical Center	Burlington	Massachusetts	01805	Recruiting
UMass Chan Medical School	Worcester	Massachusetts	01655	Active, not recruiting
Henry Ford Health	Detroit	Michigan	48202	Recruiting
Corewell Health (Former Spectrum Health)	Grand Rapids	Michigan	49503	Recruiting
Trinity Health Grand Rapids/Mercy Health	Grand Rapids	Michigan	49503	Recruiting
William Beaumont Hospital	Royal Oak	Michigan	48073	Recruiting
Trinity Health Michigan Heart - Ann Arbor	Ypsilanti	Michigan	48197	Recruiting
Essentia Health The Duluth Clinic	Duluth	Minnesota	55812	Active, not recruiting
Minneapolis Heart Institute Foundation	Minneapolis	Minnesota	55407	Recruiting
Hennepin Healthcare Research Institute	Minneapolis	Minnesota	55415	Recruiting
University of Minnesota	Minneapolis	Minnesota	55455	Recruiting
University Health Truman Medical Center	Kansas City	Missouri	64108	Withdrawn
Washington University School of Medicine	St Louis	Missouri	63110	Recruiting
Advanced Heart and Vascular Institute of Hunterdon	Flemington	New Jersey	08822	Recruiting
Hackensack Meridian Health	Hackensack	New Jersey	07601	Recruiting
Rutgers, the State University of New Jersey	Piscataway	New Jersey	08854	Recruiting
The Valley Hospital, Inc.	Ridgewood	New Jersey	07450	Recruiting
University of New Mexico Health Sciences Center	Albuquerque	New Mexico	87102	Recruiting
Presbyterian Healthcare Services	Albuquerque	New Mexico	87106	Active, not recruiting
University at Buffalo	Buffalo	New York	14214	Recruiting
NYU Langone Health	New York	New York	10016	Recruiting
Columbia University Medical Center	New York	New York	10032	Recruiting
Weill Medical College of Cornell University	New York	New York	10065	Recruiting
NewYork Presbyterian - Queens	Queens	New York	11355	Recruiting
Staten Island University Hospital-Northwell Health	Staten Island	New York	10305	Recruiting
Stony Brook University	Stony Brook	New York	11794	Recruiting
Westchester Medical Center	Valhalla	New York	10595	Recruiting
White Plains Hospital	White Plains	New York	10601	Recruiting
University of North Carolina	Chapel Hill	North Carolina	27599	Recruiting
Wake Forest Baptist Health	Winston-Salem	North Carolina	27157	Recruiting
The Lindner Center for Research and Education at The Christ Hospital	Cincinnati	Ohio	45219	Recruiting
University of Cincinnati College of Medicine	Cincinnati	Ohio	45267	Recruiting
Ohio State University Medical Center	Columbus	Ohio	43210	Recruiting
OhioHealth Research Institute	Columbus	Ohio	43214	Recruiting
Wooster Community Hospital	Wooster	Ohio	44691	Recruiting
University of Oklahoma Health Sciences Center	Oklahoma City	Oklahoma	73104	Recruiting
Cardiology Consultants of Philadelphia	Paoli	Pennsylvania	19301	Not yet recruiting
Thomas Jefferson University	Philadelphia	Pennsylvania	19144	Recruiting
Allegheny Singer Research Institute	Pittsburgh	Pennsylvania	15212	Recruiting
Penn State Health Medical Group Berks Cardiology	Wyomissing	Pennsylvania	19610	Recruiting
Rhode Island Hospital	Providence	Rhode Island	02903	Recruiting
Medical University of South Carolina	Charleston	South Carolina	29425	Recruiting
MUSC Health Heart and Vascular	Columbia	South Carolina	29204	Recruiting
Texas Cardiac Arrhythmia Research Foundation	Austin	Texas	78705	Recruiting
University of Texas Southwestern Medical Center	Dallas	Texas	75390	Recruiting
Baylor College of Medicine	Houston	Texas	77030	Recruiting
Houston Methodist Hospital	Houston	Texas	77030	Recruiting
University of Texas Health Science Center at Houston	Houston	Texas	77030	Recruiting
University of Utah	Salt Lake City	Utah	84112	Recruiting
University of Virginia	Charlottesville	Virginia	22903	Recruiting
James River Cardiology	Richmond	Virginia	23229	Recruiting
Virginia Commonwealth University	Richmond	Virginia	23284	Recruiting
St. Joseph Medical Center Tacoma	Tacoma	Washington	98405	Recruiting
University of Wisconsin	Madison	Wisconsin	53706	Recruiting
Medical College of Wisconsin Froedtert Hospital	Milwaukee	Wisconsin	53226	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05836987, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Apr 8, 2026 · Synced May 20, 2026

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The complete protocol, eligibility criteria, and contact information for NCT05836987 live on ClinicalTrials.gov.

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