A Multiple Dose Study of AVD-104 for Geographic Atrophy (GA) Secondary to Age-Related Macular Degeneration (AMD)
Public ClinicalTrials.gov record NCT05839041. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Single and Multiple Dose Study to Evaluate Safety, Pharmacokinetics, and Treatment Effect of Intravitreal AVD-104 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Investigate the Safety, Pharmacokinetics, and Treatment effects of Single and Multi-dose of Intravitreal AVD-104 in participants with geographic atrophy secondary to age-related macular degeneration.
Study identification
- NCT ID
- NCT05839041
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 300 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 55 Years to 90 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 1, 2023
- Primary completion
- Mar 31, 2026
- Completion
- Sep 30, 2026
- Last update posted
- Nov 19, 2025
2023 – 2026
United States locations
- U.S. sites
- 56
- U.S. states
- 24
- U.S. cities
- 53
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Associated Retina Consultants | Gilbert | Arizona | 85297 | — |
| Arizona Retina and Vitreous Consultants | Phoenix | Arizona | 85021 | — |
| Associated Retina Consultants | Scottsdale | Arizona | 85260 | — |
| Retina Vitreous Associates Medical Group | Beverly Hills | California | 90211 | — |
| Macula & Retina Institute | Glendale | California | 91203 | — |
| Northern California Retina Vitreous Associates | Mountain View | California | 94040 | — |
| Kaiser Permanente | Riverside | California | 92505 | — |
| Retinal Consultants Medical Group, Inc. | Sacramento | California | 95825 | — |
| Retinal Consultants Medical Group | Sacramento | California | 95841 | — |
| West Coast Retina | San Francisco | California | 94101 | — |
| RCA: California Retina Consultants | Santa Barbara | California | 93103 | — |
| Retina Group of New England, PC | Waterford | Connecticut | 06385 | — |
| Rand Eye Institute | Deerfield Beach | Florida | 33064 | — |
| Retina Group of Florida | Fort Lauderdale | Florida | 33308 | — |
| Florida Retina Institute | Orlando | Florida | 32806 | — |
| Retina Specialty Institute | Pensacola | Florida | 32503 | — |
| Retina Vitreous Associates of Florida | St. Petersburg | Florida | 33711 | — |
| Southern Vitreoretinal Associates | Tallahassee | Florida | 32308 | — |
| Center for Retina & Macular Disease | Winter Haven | Florida | 33880 | — |
| Southeast Retina Center | Augusta | Georgia | 30909 | — |
| University Retina and Macula Associates | Chicago | Illinois | 60439 | — |
| Illinois Retina Associates | Oak Park | Illinois | 60304 | — |
| Midwest Eye Institute | Indianapolis | Indiana | 46290 | — |
| Cumberland Valley Retina Consultants | Hagerstown | Maryland | 21740 | — |
| Ophthalmic Consultants of Boston | Boston | Massachusetts | 02114 | — |
| New England Retina Consultants | Springfield | Massachusetts | 01107 | — |
| Retina Specialists of Michigan | Grand Rapids | Michigan | 49546 | — |
| Associated Retinal Consultants | Royal Oak | Michigan | 48073 | — |
| Retina Consultants of Minnesota | Minneapolis | Minnesota | 55435 | — |
| Mississippi Retina Associates | Jackson | Mississippi | 39202 | — |
| Sierra Eye Associates | Reno | Nevada | 89502 | — |
| Retina Center of New Jersey | Bloomfield | New Jersey | 07003 | — |
| NJ Retina | Edison | New Jersey | 08820 | — |
| Retina-Vitreous Surgeons of Central NY | Syracuse | New York | 13088 | — |
| Long Island Vitreoretinal Consultants | Westbury | New York | 11590 | — |
| North Carolina Retina Associates | Wake Forest | North Carolina | 27587 | — |
| Retina Associates of Cleveland, Inc | Beachwood | Ohio | 44122 | — |
| Retina Associates of Cleveland | Cleveland | Ohio | 44130 | — |
| Retina Vitreous Center | Edmond | Oklahoma | 73013 | — |
| Mid-Atlantic Retina | Bethlehem | Pennsylvania | 18017 | — |
| Erie Retina Research, LLC | Erie | Pennsylvania | 16507 | — |
| Retina Consultants of Charleston | Charleston | South Carolina | 29414 | — |
| Palmetto Retina Center | West Columbia | South Carolina | 29169 | — |
| Tennessee Retina | Nashville | Tennessee | 37203 | — |
| Retina Research Institute of Texas Abilene TX | Abilene | Texas | 79606 | — |
| Texas Retina Associates | Arlington | Texas | 76012 | — |
| Austin Retina Associates | Austin | Texas | 78705 | — |
| Retina Foundation of the Southwest | Dallas | Texas | 75231 | — |
| Texas Retina Associates | Dallas | Texas | 75231 | — |
| Texas Retina Associates | Fort Worth | Texas | 76104 | — |
| Valley Retina Institute | McAllen | Texas | 78504 | — |
| Retina Consultants of Texas | San Antonio | Texas | 78240 | — |
| Retina Consultants of Texas | San Antonio | Texas | 78503 | — |
| Retina Consultants of Texas | The Woodlands | Texas | 77384 | — |
| Rocky Mountain Retina Consultants | Salt Lake City | Utah | 84107 | — |
| Spokane Eye Clinic | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05839041, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 19, 2025 · Synced Sep 13, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05839041 live on ClinicalTrials.gov.