ClinicalTrials.gov record
Program to Assess Adverse Events and Change in Disease Activity of Oral Upadacitinib in Adult Participants With Moderate to Severe Systemic Lupus Erythematosus
ClinicalTrials.gov ID: NCT05843643
Public ClinicalTrials.gov record NCT05843643. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
ClinicalTrials.gov public records Last synced May 5, 2026, 7:21 AM EDT
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
SELECT-SLE: A Phase 3 Program to Evaluate the Safety and Efficacy of Upadacitinib in Subjects With Moderately to Severely Active SLE
Study identification
- NCT ID
- NCT05843643
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- AbbVie
- Industry
- Enrollment
- 1,014 participants
Conditions and interventions
Conditions
Interventions
- Placebo Drug
- Upadacitinib Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 63 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 24, 2023
- Primary completion
- Feb 28, 2027
- Completion
- Sep 30, 2027
- Last update posted
- Apr 27, 2026
2023 – 2027
United States locations
- U.S. sites
- 132
- U.S. states
- 28
- U.S. cities
- 110
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| AZ Arthritis and Rheumatology /ID# 261848 | Chandler | Arizona | 85225-2906 | — |
| AZ Arthritis and Rheumotology Research, PLLC - Flagstaff /ID# 254767 | Flagstaff | Arizona | 86001-6299 | — |
| Arizona Arthritis & Rheumatology Research, PLLC /ID# 252820 | Gilbert | Arizona | 85297-7336 | — |
| Arizona Arthritis and Rheumatology Research - Glendale Office /ID# 252824 | Glendale | Arizona | 85306-9802 | — |
| Arizona Arthritis & Rheumatology Research, PLLC /ID# 261845 | Mesa | Arizona | 85210-6871 | — |
| Arizona Arthritis & Rheumatology Research /ID# 273555 | Peoria | Arizona | 85381 | — |
| Arizona Arthritis & Rheumatology Associates - East Bell Road /ID# 252831 | Phoenix | Arizona | 85032 | — |
| Arizona Arthritis & Rheumatology Research, PLLC /ID# 252825 | Phoenix | Arizona | 85037 | — |
| HonorHealth Rheumatology /ID# 261953 | Scottsdale | Arizona | 85258-4668 | — |
| Arizona Arthritis & Rheumatology Associates - Tucson /ID# 252828 | Tucson | Arizona | 85704 | — |
| Arthritis and Rheumatism Associates /ID# 253033 | Jonesboro | Arkansas | 72401-6251 | — |
| Kaiser Permanente Lakeview Medical Offices /ID# 253906 | Anaheim | California | 92807-3028 | — |
| David S. Hallegua MD, A Professional Corporation /ID# 253902 | Beverly Hills | California | 90211 | — |
| Wallace and Lee Center /ID# 275129 | Beverly Hills | California | 90211 | — |
| Wallace Rheumatic Studies Center, LLC /ID# 252806 | Beverly Hills | California | 90211 | — |
| Advanced Clinical Research Center, LLC dba TriWest Research Associates /ID# 272870 | Chula Vista | California | 91910 | — |
| Providence - St. Jude Medical Center /ID# 252822 | Fullerton | California | 92835 | — |
| Private Practice - Dr. Chandrakant V. Mehta /ID# 275100 | Hemet | California | 92543 | — |
| Newport Huntington Medical Group /ID# 252827 | Huntington Beach | California | 92648-5994 | — |
| Moores Cancer Center at UC San Diego /ID# 253903 | La Jolla | California | 92093 | — |
| Arthritis & Osteo Medical Ctr /ID# 252812 | La Palma | California | 90623-1728 | — |
| Wagdy Kades, M.D., Inc /ID# 272065 | Los Angeles | California | 90017 | — |
| Providence St. Johns Health Center /ID# 253905 | Santa Monica | California | 90404-2303 | — |
| Millennium Clinical Trials /ID# 252817 | Thousand Oaks | California | 91360-3951 | — |
| Cohen Medical Centers /ID# 268524 | Thousand Oaks | California | 91360 | — |
| Solace Research /ID# 275198 | Tustin | California | 92780 | — |
| Upland Rheumatology Center /ID# 268623 | Upland | California | 91786 | — |
| University of Colorado Hospital /ID# 253184 | Aurora | Colorado | 80045 | — |
| Denver Arthritis Clinic /ID# 253189 | Denver | Colorado | 80230 | — |
| Yale University School of Medicine /ID# 254567 | New Haven | Connecticut | 06510 | — |
| Arthritis and Rheumatic Disease Specialties /ID# 253624 | Aventura | Florida | 33180 | — |
| HARAC Research Corp. /ID# 254922 | Avon Park | Florida | 33825-2958 | — |
| Rheumatology Associates of South Florida (RASF) - Clinical Research /ID# 253623 | Boca Raton | Florida | 33486 | — |
| Mdr Core Network, Inc /Id# 276704 | Boynton Beach | Florida | 33426 | — |
| Bay Area Arthritis and Osteo /ID# 253597 | Brandon | Florida | 33511 | — |
| GNP Consultants, dba, GNP Research /ID# 272868 | Cooper City | Florida | 33024 | — |
| Duplicate_Believe Clinical Trials /ID# 255427 | Coral Springs | Florida | 33065 | — |
| International Medical Research /ID# 253617 | Daytona Beach | Florida | 32117 | — |
| Omega Research Debary, LLC /ID# 254939 | DeBary | Florida | 32713-2260 | — |
| University of Florida /ID# 261984 | Gainesville | Florida | 32610-3008 | — |
| Finlay Medical Research - Greenacres /ID# 274902 | Greenacres City | Florida | 33467 | — |
| Evolution Research Center /ID# 272991 | Hialeah | Florida | 33012 | — |
| Neoclinical Research /ID# 253614 | Hialeah | Florida | 33016-1897 | — |
| South Florida Rheumatology /ID# 268525 | Hollywood | Florida | 33026 | — |
| Encore Research Group-Jacksonville Center for Clinical Research /ID# 257272 | Jacksonville | Florida | 32216 | — |
| UF Health Rheumatology /ID# 255351 | Jacksonville | Florida | 32256 | — |
| Life Clinical Trials /ID# 253615 | Margate | Florida | 33063 | — |
| Lakes Research, LLC /ID# 253621 | Miami | Florida | 33014 | — |
| University of Miami, Division of Rheumatology /ID# 261594 | Miami | Florida | 33136-2107 | — |
| Ezy Medical Research /ID# 276221 | Miami | Florida | 33175 | — |
| HMD Research LLC /ID# 253595 | Orlando | Florida | 32819 | — |
| University of Central Florida /ID# 261112 | Orlando | Florida | 32827-7664 | — |
| Millennium Research /ID# 253600 | Ormond Beach | Florida | 32174 | — |
| Vitalia Research /ID# 272642 | Palm Beach Gardens | Florida | 33410 | — |
| Believe Clinical Trials /ID# 277004 | Plant City | Florida | 33563 | — |
| IRIS Research and Development, LLC /ID# 253618 | Plantation | Florida | 33324 | — |
| BayCare Medical Group /ID# 253593 | St. Petersburg | Florida | 33705 | — |
| Clinical Research Of West Florida - Tampa - North Howard Avenue /ID# 253602 | Tampa | Florida | 33606 | — |
| Clinical Research Of West Florida - Tampa - North Howard Avenue /ID# 253899 | Tampa | Florida | 33606 | — |
| Baycare Medical Group - Tampa /ID# 255135 | Tampa | Florida | 33614 | — |
| Emory University School Of Medicine - Atlanta /ID# 261529 | Atlanta | Georgia | 30322 | — |
| Trinity Research Centers /ID# 262039 | Kennesaw | Georgia | 30144-1762 | — |
| Atlanta Research Center For Rheumatology - Marietta /ID# 253610 | Marietta | Georgia | 30060 | — |
| Arthritis and Rheumatology Center PC /ID# 275994 | Roswell | Georgia | 30076 | — |
| Immunology and Rheumatology Research Associates LLC /ID# 267582 | Suwanee | Georgia | 30024-7290 | — |
| University of Illinois Hospital and Health Sciences System /ID# 263014 | Chicago | Illinois | 60607 | — |
| Northwestern University Feinberg School of Medicine /ID# 264090 | Chicago | Illinois | 60611-2927 | — |
| Next Innovative Clinical Research - Chicago /ID# 268739 | Chicago | Illinois | 60616 | — |
| University of Chicago Medical Center /ID# 263162 | Chicago | Illinois | 60637 | — |
| Illinois Bone & Joint Institute - Morton /ID# 274455 | Morton | Illinois | 60053 | — |
| Advanced Quality Medical Research /ID# 254983 | Orland Park | Illinois | 60462 | — |
| OrthoIllinois /ID# 253188 | Rockford | Illinois | 61114-4937 | — |
| Greater Chicago Specialty Physicians /ID# 253021 | Schaumburg | Illinois | 60195-3106 | — |
| Clinic Of Dr. Robert Hozman/Clinical Investigation Specialists, Inc /ID# 253020 | Skokie | Illinois | 60076 | — |
| NorthShore University HealthSystem - Skokie /ID# 254568 | Skokie | Illinois | 60077 | — |
| Deerbrook Medical Associates /ID# 253029 | Vernon Hills | Illinois | 60061 | — |
| Willow Rheumatology and Wellness, PLLC /ID# 253018 | Willowbrook | Illinois | 60527 | — |
| Western KY Rheumatology /ID# 254937 | Hopkinsville | Kentucky | 42240 | — |
| Accurate Clinical Research (SMO/Network/Consortium) /ID# 272647 | Lake Charles | Louisiana | 70605 | — |
| Willis Knighton /ID# 256343 | Shreveport | Louisiana | 71103-3920 | — |
| University of Maryland, Baltimore /ID# 262556 | Baltimore | Maryland | 21201 | — |
| UMass Memorial Medical Center /ID# 262742 | Worcester | Massachusetts | 01655 | — |
| Clinical Research Institute Of Michigan /ID# 273051 | Clinton Township | Michigan | 48038 | — |
| AA Medical Research Center - Grand Blanc /ID# 253028 | Grand Blanc | Michigan | 48439 | — |
| June DO, PC /ID# 253030 | Lansing | Michigan | 48911 | — |
| Kansas City Physician Partners /ID# 254786 | Kansas City | Missouri | 64151 | — |
| Logan Health Research - Glacier View Research Institute - Rheumatology /ID# 252808 | Kalispell | Montana | 59901 | — |
| Dartmouth-Hitchcock Medical Center /ID# 254923 | Lebanon | New Hampshire | 03756 | — |
| Arthritis and Osteoporosis Associates of New Mexico /ID# 252818 | Las Cruces | New Mexico | 88011 | — |
| Inspire Santa Fe Medical Group /ID# 275947 | Santa Fe | New Mexico | 87505 | — |
| Joseph S. and Diane H. Steinberg Ambulatory Care Center /ID# 253592 | Brooklyn | New York | 11201-5501 | — |
| NYU Langone Orthopedic Center /ID# 253613 | New York | New York | 10016-2772 | — |
| St. Lawrence Health System /ID# 253598 | Potsdam | New York | 13676 | — |
| Urban Health Plan /ID# 268059 | The Bronx | New York | 10459 | — |
| Joint And Muscle Research Institute /ID# 272845 | Charlotte | North Carolina | 28204 | — |
| DJL Clinical Research, PLLC /ID# 253620 | Charlotte | North Carolina | 28211 | — |
| Raleigh Medical Group /ID# 256328 | Raleigh | North Carolina | 27609 | — |
| Accellacare - Salisbury /ID# 253608 | Salisbury | North Carolina | 28144-2735 | — |
| Atrium Health Wake Forest Baptist Medical Center /ID# 254125 | Winston-Salem | North Carolina | 27157 | — |
| University of Cincinnati Medical Center /ID# 259174 | Cincinnati | Ohio | 45219-2364 | — |
| Paramount Medical Research and Consulting /ID# 253016 | Middleburg Heights | Ohio | 44130 | — |
| Clinical Research Source, Inc. /ID# 253027 | Perrysburg | Ohio | 43551 | — |
| Oklahoma Medical Research Foundation /ID# 263509 | Oklahoma City | Oklahoma | 73104 | — |
| Rheumatology Associates of Oklahoma /ID# 253012 | Oklahoma City | Oklahoma | 73116-7226 | — |
| Clinical Research of Philadelphia, LLC /ID# 254156 | Philadelphia | Pennsylvania | 19114 | — |
| Albert Einstein Medical Center /ID# 256661 | Philadelphia | Pennsylvania | 19141 | — |
| University of Pittsburgh Medical Center /ID# 263686 | Pittsburgh | Pennsylvania | 15213 | — |
| Low Country Rheumatology /ID# 272956 | Summerville | South Carolina | 29486 | — |
| West Tennessee Research Institute /ID# 252807 | Jackson | Tennessee | 38305 | — |
| Shelby Research /ID# 256937 | Memphis | Tennessee | 38119 | — |
| Arthritis and Rheumatology Research Institute, PLLC /ID# 253014 | Allen | Texas | 75013-6147 | — |
| Rheumatology Associates /ID# 276066 | Arlington | Texas | 76012 | — |
| Arthritis Care of Texas /ID# 261719 | Corpus Christi | Texas | 78415-1800 | — |
| Texas Arthritis Center /ID# 277049 | El Paso | Texas | 79902 | — |
| JPS Rheumatology Clinic /ID# 253185 | Fort Worth | Texas | 76104-4917 | — |
| Arthiritis and Rheumatology Specialists PA /ID# 255950 | Fort Worth | Texas | 76177 | — |
| Integrative Rheumatology of South Texas - Harlingen /ID# 261977 | Harlingen | Texas | 78550 | — |
| Accurate Clinical Research - Houston /ID# 276220 | Houston | Texas | 77089-6142 | — |
| Accurate Clinical Research Katy /ID# 276459 | Katy | Texas | 77449 | — |
| R & H Clinical Research - Katy /ID# 254126 | Katy | Texas | 77450-2244 | — |
| Biopharma Informatic /ID# 273651 | Katy | Texas | 77494 | — |
| Valley Arthritis Center /ID# 253022 | McAllen | Texas | 78501-1401 | — |
| Texas Rheumatology Research Institute Llc /Id# 253013 | Plano | Texas | 75024 | — |
| Epic Medical Research /ID# 255326 | Red Oak | Texas | 75154 | — |
| Sun Research Institute /ID# 255832 | San Antonio | Texas | 78215 | — |
| Clinical Trials of Texas, Inc /ID# 254949 | San Antonio | Texas | 78229 | — |
| Epic Medical Research- San Marcos /ID# 278360 | San Marcos | Texas | 78666 | — |
| Fort Bend Rheumatology Associates, PLLC /ID# 268492 | Sugar Land | Texas | 77479 | — |
| DM Clinical Research - Tomball /ID# 255134 | Tomball | Texas | 77375 | — |
| Carilion Roanoke Memorial Hospital /ID# 253374 | Roanoke | Virginia | 24014 | — |
| Rheumatology & Pulmonary Clinic /ID# 273561 | Beckley | West Virginia | 25801 | — |
| Wisconsin Medical Center /ID# 256660 | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 237 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05843643, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 27, 2026 · Synced May 5, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05843643 live on ClinicalTrials.gov.