Direct Access Carotid Artery Stenting Using the Neuroguard IEP System (PERFORMANCE III)
Public ClinicalTrials.gov record NCT05845710. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Protection Against Emboli During caRotid Artery Stenting Using a Neuroguard IEP® Direct 3-in-1 Delivery System Comprised oF a pOst-dilation Balloon, integRated eMbolic Filter, and A Novel Carotid stEnt - the PERFORMANCE III Study
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The PERFORMANCE III study is a prospective, multicenter single-arm, open label study to evaluate the safety and effectiveness of the Neuroguard IEP® Direct System for the treatment of carotid artery stenosis in subjects at elevated risk for carotid endarterectomy (CEA). Eligible patients greater than or equal to 20 years of age and less than or equal to 82 years of age, are those who have been diagnosed with either de-novo atherosclerotic or post CEA restenotic lesion(s) in the internal carotid arteries (ICA) or at the carotid bifurcation with greater than or equal to 50% stenosis if symptomatic or greater than or equal to 70% stenosis if asymptomatic.
Study identification
- NCT ID
- NCT05845710
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 178 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 20 Years to 82 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 5, 2023 (Actual)
- Primary completion
- Aug 12, 2025 (Actual)
- Completion
- Aug 12, 2025 (Actual)
- Last update posted
- Mar 6, 2026
2023 – 2025
United States locations
- U.S. sites
- 30
- U.S. states
- 17
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Honor Health | Scottsdale | Arizona | 85258 | — |
| Hartford Hospital | Hartford | Connecticut | 06102 | — |
| MedStar Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| Manatee Memorial Hospital | Bradenton | Florida | 34208 | — |
| Delray Medical Center | Delray Beach | Florida | 33484 | — |
| Mount Sinai Vascular Institute | Miami Beach | Florida | 33140 | — |
| AdventHealth Orlando | Orlando | Florida | 32803 | — |
| Indiana University Methodist Hospital | Indianapolis | Indiana | 46202 | — |
| Southcoast Health | New Bedford | Massachusetts | 02720 | — |
| McLaren Center for Research and Innovation | Bay City | Michigan | 48708 | — |
| Hackensack University Medical Center | Hackensack | New Jersey | 07601 | — |
| University at Buffalo Neurosurgery - Jacobs Institute | Buffalo | New York | 14203 | — |
| Sisters of Charity Hospital | Buffalo | New York | 14214 | — |
| Northwell Health | Lake Success | New York | 11042 | — |
| Mount Sinai Medical Center | New York | New York | 10029 | — |
| UNC Hospital | Chapel Hill | North Carolina | 27514 | — |
| Atrium Health - Sanger Heart and Vascular | Charlotte | North Carolina | 28204 | — |
| North Carolina Heart and Vascular Research | Raleigh | North Carolina | 27607 | — |
| TriHealth (Bethesda North Hospital) | Cincinnati | Ohio | 45242 | — |
| Cleveland Clinic | Cleveland | Ohio | 44195 | — |
| OhioHealth Research Institute | Columbus | Ohio | 43214 | — |
| St. Francis Hospital | Tulsa | Oklahoma | 74136 | — |
| Allegheny General Hospital | Pittsburgh | Pennsylvania | 15212 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Prisma Health | Greenville | South Carolina | 29615 | — |
| Vanderbilt University | Nashville | Tennessee | 37232-5545 | — |
| St. David's Healthcare | Austin | Texas | 78756 | — |
| Baylor Scott and White Research Institute | Dallas | Texas | 75246 | — |
| UT Southwestern Medical Center | Dallas | Texas | 75390 | — |
| Sentara Norfolk General Hospital | Norfolk | Virginia | 23507 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05845710, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 6, 2026 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05845710 live on ClinicalTrials.gov.