Independent directory Public ClinicalTrials.gov records United States
ClinicalTrials.gov record
Recruiting Phase 1 Interventional

Study of MK-0472 in Participants With Advanced/Metastatic Solid Tumors (MK-0472-001)

ClinicalTrials.gov ID: NCT05853367

Public ClinicalTrials.gov record NCT05853367. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 12, 2026, 4:25 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 1/1b Open-label, Multicenter Clinical Study of MK-0472 as Monotherapy and Combination Therapy in Participants With Advanced/Metastatic Solid Tumors.

Study identification

NCT ID
NCT05853367
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 1
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Enrollment
178 participants

Conditions and interventions

Interventions

  • MK-0472 Drug
  • MK-1084 Drug
  • Pembrolizumab Biological

Drug · Biological

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 5, 2023
Primary completion
Feb 11, 2028
Completion
Feb 11, 2028
Last update posted
Mar 12, 2026

2023 – 2028

United States locations

U.S. sites
4
U.S. states
3
U.S. cities
4
Facility City State ZIP Site status
Northwestern Memorial Hospital ( Site 0002) Chicago Illinois 60611 Recruiting
The University of Louisville, James Graham Brown Cancer Center ( Site 0004) Louisville Kentucky 40202 Recruiting
John Theurer Cancer Center at Hackensack University Medical Center ( Site 0001) Hackensack New Jersey 07601 Recruiting
Rutgers Cancer Institute of New Jersey ( Site 0005) New Brunswick New Jersey 08901 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 21 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05853367, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 12, 2026 · Synced May 12, 2026

Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.

Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05853367 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →