A Proof of Concept Trial Investigating Safety and Efficacy of APG-157 in Oral Dysplasia

ClinicalTrials.gov ID: NCT05865028

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Official title

Phase II A Proof of Concept Trial Investigating Safety and Efficacy of APG-157 in Oral Dysplasia

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to assess whether APG-157 can reduce the tumor size in participants with the study disease. Another purpose is to find out about the effects of APG-157 on certain tumor markers and oral rinses in participants with the study disease.

Study identification

NCT ID: NCT05865028
Recruitment status: Recruiting
Study type: Interventional
Phase: Phase 2
Lead sponsor: Elizabeth J Franzmann; Other
Enrollment: 32 participants

Conditions and interventions

Conditions

Interventions

APG-157 Drug

Drug

Eligibility (public fields only)

Age range: 18 Years and older
Sex: All
Healthy volunteers: Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date: May 24, 2023 (Actual)
Primary completion: May 24, 2027 (Estimated)
Completion: May 24, 2028 (Estimated)
Last update posted: Jan 14, 2026

2023 – 2028

United States locations

U.S. sites: 1
U.S. states: 1
U.S. cities: 1

Facility	City	State	ZIP	Site status
University of Miami	Miami	Florida	33136	Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows: Public field values for ClinicalTrials.gov record NCT05865028, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do: No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from: Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh: Last update posted Jan 14, 2026 · Synced Nov 15, 2026