RewinD-LB - Clinical Study of Neflamapimod in Patients With Dementia With Lewy Bodies
Public ClinicalTrials.gov record NCT05869669. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b Clinical Study of the P38 Alpha Kinase Inhibitor Neflamapimod in Patients With Dementia With Lewy Bodies
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to determine whether neflamapimod can improve learning skills, problem solving skills, and memory loss in people diagnosed with DLB. More specifically, improvement in verbal learning, memory, and attention, as well as cognitive and functional performance will be measured.
Study identification
- NCT ID
- NCT05869669
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 159 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 55 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 1, 2023 (Actual)
- Primary completion
- May 29, 2025 (Actual)
- Completion
- Jun 16, 2025 (Actual)
- Last update posted
- Sep 3, 2026
2023 – 2025
United States locations
- U.S. sites
- 29
- U.S. states
- 18
- U.S. cities
- 29
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Barrow Neurological Institute | Phoenix | Arizona | 85013 | — |
| Banner Sun Health Research Institute | Sun City | Arizona | 85351 | — |
| Banner Alzheimer's Institute - Edson Family Lewy Body Dementia Center | Tucson | Arizona | 85718 | — |
| UCSD Health Sciences - Movement Disorders Center | La Jolla | California | 92037 | — |
| Hoag Memorial Hospital Presbyterian | Newport Beach | California | 92663 | — |
| Stanford Neuroscience Health Center | Palo Alto | California | 94304 | — |
| SC3 Research Group | Pasadena | California | 91105 | — |
| University of Colorado - Dept of Neurology | Aurora | Colorado | 80045 | — |
| Georgetown Univ Hospital - Dept of Neurology | Washington D.C. | District of Columbia | 20007 | — |
| JEM Research Institute | Lake Worth | Florida | 33462 | — |
| ClinCloud | Melbourne | Florida | 32940 | — |
| AdventHealth Neuroscience Research | Orlando | Florida | 32804 | — |
| Panhandle Research and Medical Clinic | Pensacola | Florida | 32503 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Tandem Clinical Research | Marrero | Louisiana | 70072 | — |
| Johns Hopkins School of Medicine - Dept of Neurology | Baltimore | Maryland | 21287 | — |
| Mass General Hospital/Harvard Medical School - Dept of Neurology | Charlestown | Massachusetts | 02129 | — |
| Mayo Clinic - Alzheimer's Disease Research Center | Rochester | Minnesota | 55905 | — |
| University of Nebraska Medical Center - Dept of Neurological Sciences | Omaha | Nebraska | 68198 | — |
| Cleveland Clinic - Lou Ruvo Center for Brain Health | Las Vegas | Nevada | 89106 | — |
| Columbia University - Taub Institute/Neurology Dept | New York | New York | 10032 | — |
| University of North Carolina - Dept of Neurology | Chapel Hill | North Carolina | 27599 | — |
| NeuroScience Research Center | Canton | Ohio | 44718 | — |
| Cleveland Clinic - Center for Brain Health | Cleveland | Ohio | 44195 | — |
| Ohio State University - Dept of Neurology | Columbus | Ohio | 43221 | — |
| Center for Cognitive Health | Portland | Oregon | 97225 | — |
| Houston Methodist Hospital - Stanley Appel Neurology Dept | Houston | Texas | 77030 | — |
| Sana Research | Arlington | Virginia | 22205 | — |
| Virginia Commonwealth University - Parkinson's and Movement Disorders Center | Richmond | Virginia | 23298 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 11 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05869669, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 3, 2026 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05869669 live on ClinicalTrials.gov.