BPL-003 Efficacy and Safety in Treatment Resistant Depression
Public ClinicalTrials.gov record NCT05870540. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Quadruple Masked, Dose-Finding Study to Evaluate the Efficacy and Safety of Intranasal BPL-003, With Open Label Extension, in Patients With Treatment-Resistant Depression
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a Phase 2 study randomized, quadruple-masked, multi-center trial with an open-label extension (OLE), designed to investigate the efficacy and safety of BPL-003 in patients with treatment resistant depression (TRD).
Study identification
- NCT ID
- NCT05870540
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 196 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 14, 2023 (Actual)
- Primary completion
- Mar 28, 2025 (Actual)
- Completion
- Jul 3, 2025 (Actual)
- Last update posted
- Sep 10, 2026
2023 – 2025
United States locations
- U.S. sites
- 19
- U.S. states
- 14
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UAB School of Public Health, Department of Health Behavior | Birmingham | Alabama | 35209 | — |
| Woodland Research Northwest | Rogers | Arkansas | 72758 | — |
| Kadima Neuropsychiatry Institute | San Diego | California | 92037 | — |
| San Francisco Insight and Integration Center | San Francisco | California | 94114 | — |
| Pacific Neuroscience Institute, Treatment and Research in Psychedelics (TRIP) Program | Santa Monica | California | 90404 | — |
| Wholeness Center | Fort Collins | Colorado | 80525 | — |
| Segal Trials Center for Psychedelic and Cannabis Research | Lauderhill | Florida | 33319 | — |
| Emory University, Brain Health Center, Department of Psychiatry and Behavioral Sciences | Atlanta | Georgia | 30329 | — |
| CenExel ACMR | Atlanta | Georgia | 30331 | — |
| CenExel iResearch | Decatur | Georgia | 30030 | — |
| Sunstone Medical PC (Sunstone Therapies / Aquilino Cancer Center) | Rockville | Maryland | 20850 | — |
| Boston Clinical Trials | Boston | Massachusetts | 02131 | — |
| CenExel HRI | Berlin | New Jersey | 08009 | — |
| New York State Psychiatric Institute | New York | New York | 10032 | — |
| Portland Psychotherapy | Portland | Oregon | 97227 | — |
| Insite clinical research | DeSoto | Texas | 75115 | — |
| AIM Trials | Plano | Texas | 75093 | — |
| Cedar Clinical Research | Draper | Utah | 84020 | — |
| University of Wisconsin, Dept of Family Medicine & Community Health | Madison | Wisconsin | 53705 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 23 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05870540, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 10, 2026 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05870540 live on ClinicalTrials.gov.