The PROTEMBO Trial
Public ClinicalTrials.gov record NCT05873816. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Cerebral Protection in Transcatheter Aortic Valve Replacement: The PROTEMBO Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The goal of this prospective, multi-center, randomized, controlled study is to compare the safety and efficacy of the ProtEmbo Cerebral Embolic Protection device to a hybrid control (no embolic protection device ('No Device') and the Sentinel device) in subjects with severe symptomatic native aortic valve stenosis indicated undergoing a TAVR procedure.
Study identification
- NCT ID
- NCT05873816
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 284 participants
Conditions and interventions
Conditions
Interventions
Device
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Mar 21, 2024 (Actual)
- Primary completion
- Oct 18, 2025 (Actual)
- Completion
- Dec 31, 2025 (Actual)
- Last update posted
- Jan 9, 2026
2024 – 2025
United States locations
- U.S. sites
- 15
- U.S. states
- 10
- U.S. cities
- 12
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Tucson Medical Center Health | Tucson | Arizona | 85712 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| BayCare Health System / Morton Plant Hospital | Clearwater | Florida | 33756 | — |
| University of Michigan | Ann Arbor | Michigan | 48109 | — |
| Saint Luke's Hospital of Kansas City | Kansas City | Missouri | 64111 | — |
| Washington University - St. Louis | St Louis | Missouri | 63110 | — |
| Morristown Medical Center | Morristown | New Jersey | 07690 | — |
| State University of New York at Buffalo | Buffalo | New York | 14203 | — |
| NYU Langone | New York | New York | 10016 | — |
| Mount Sinai Hospital | New York | New York | 10029 | — |
| Columbia University Medical Center / NYPH | New York | New York | 10032 | — |
| Weill Medical College / Cornell University | New York | New York | 10065 | — |
| University of Texas, Memorial Hermann Hospital | Houston | Texas | 77030 | — |
| University of Virginia, Charlottesville | Charlottesville | Virginia | 22908 | — |
| Medical College of Wisconsin | Milwaukee | Wisconsin | 53226 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 5 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05873816, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 9, 2026 · Synced Oct 27, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05873816 live on ClinicalTrials.gov.