A Clinical Study of Efinopegdutide in Participants With Precirrhotic Nonalcoholic Steatohepatitis (NASH) (MK-6024-013)
Public ClinicalTrials.gov record NCT05877547. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2b Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Efinopegdutide (MK-6024) in Adults With Precirrhotic Nonalcoholic Steatohepatitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to learn how well efinopegdutide works compared to placebo in people who have non-alcoholic steatohepatitis (NASH). Researchers will also learn about the safety and benefit of efinopegdutide and how well people tolerate the medicine. The main goal of the study is to compare how many people taking efinopegdutide or placebo stop showing evidence of NASH without liver scarring getting worse.
Study identification
- NCT ID
- NCT05877547
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 381 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 23, 2023 (Actual)
- Primary completion
- Dec 29, 2025 (Actual)
- Completion
- Dec 29, 2025 (Actual)
- Last update posted
- Jan 12, 2026
2023 – 2025
United States locations
- U.S. sites
- 42
- U.S. states
- 14
- U.S. cities
- 39
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The Institute for Liver Health II dba Arizona Clinical Trial-The Institute for Liver Health ( Site 3 | Chandler | Arizona | 85224 | — |
| The Institute for Liver Health II dba Arizona Clinical Trials - Peoria ( Site 3289) | Peoria | Arizona | 85381 | — |
| The Institute for Liver Health II dba Arizona Liver Health-Tucson ( Site 3218) | Tucson | Arizona | 85712 | — |
| Del Sol Research Management, LLC ( Site 3211) | Tucson | Arizona | 85715 | — |
| Om Research - Apple Valley ( Site 3244) | Apple Valley | California | 92307 | — |
| Om Research LLC ( Site 3245) | Camarillo | California | 93012 | — |
| Velocity Clinical Research, Gardena ( Site 3225) | Gardena | California | 90247 | — |
| Velocity Clinical Research, Huntington Park ( Site 3217) | Huntington Park | California | 90255 | — |
| Velocity Clinical Research, San Diego ( Site 3226) | La Mesa | California | 91942 | — |
| Om Research LLC ( Site 3229) | Lancaster | California | 93534 | — |
| Velocity Clinical Research, Westlake ( Site 3216) | Los Angeles | California | 90057 | — |
| Velocity Clinical Research, Panorama City ( Site 3214) | Panorama City | California | 91402 | — |
| California Liver Research Institute ( Site 3232) | Pasadena | California | 91105 | — |
| Clinical Trials Research ( Site 3230) | Sacramento | California | 95821 | — |
| Excel Medical Clinical Trials ( Site 3246) | Boca Raton | Florida | 33434 | — |
| Synergy Healthcare ( Site 3286) | Bradenton | Florida | 34208 | — |
| Synergy Healthcare LLC ( Site 3290) | Brandon | Florida | 33511 | — |
| Top Medical Research ( Site 3209) | Cutler Bay | Florida | 33189 | — |
| Covenant Metabolic Specialists, LLC ( Site 3231) | Fort Myers | Florida | 33912 | — |
| Velocity Clinical Research, Hallandale Beach ( Site 3241) | Hallandale | Florida | 33009 | — |
| Indago Research & Health Center, Inc ( Site 3207) | Hialeah | Florida | 33012 | — |
| Sweet Hope Research Specialty, Inc-Research ( Site 3200) | Hialeah | Florida | 33016 | — |
| Florida Research Institute ( Site 3243) | Lakewood Rch | Florida | 34211 | — |
| Genoma Research Group ( Site 3242) | Miami | Florida | 33173 | — |
| Floridian Clinical Research, LLC ( Site 3203) | Miami Lakes | Florida | 33016-1518 | — |
| Southeast Clinical Research Center ( Site 3288) | Dalton | Georgia | 30720 | — |
| Eagle Clinical Research ( Site 3233) | Chicago | Illinois | 60621 | — |
| University of Iowa ( Site 3213) | Iowa City | Iowa | 52242 | — |
| Kansas City Research Institute ( Site 3249) | Kansas City | Missouri | 64131 | — |
| The Machuca Foundation ( Site 3234) | Las Vegas | Nevada | 89101 | — |
| Velocity Clinical Research, Syracuse ( Site 3227) | East Syracuse | New York | 13057 | — |
| New York Gastroenterology Associates ( Site 3252) | New York | New York | 10075 | — |
| Velocity Clinical Research, Cincinnati ( Site 3237) | Cincinnati | Ohio | 45242 | — |
| Velocity Clinical Research, Providence ( Site 3222) | East Greenwich | Rhode Island | 02818 | — |
| Velocity Clinical Research, Austin ( Site 3235) | Austin | Texas | 78759 | — |
| South Texas Research Institute - Brownsville ( Site 3285) | Brownsville | Texas | 78520 | — |
| Velocity Clinical Research, Dallas ( Site 3220) | Dallas | Texas | 75230 | — |
| Houston Research Institute ( Site 3262) | Houston | Texas | 77079 | — |
| American Research Corporation ( Site 3202) | San Antonio | Texas | 78215 | — |
| Pinnacle Clinical Research ( Site 3284) | San Antonio | Texas | 78229 | — |
| Velocity Clinical Research, Salt Lake City ( Site 3223) | West Jordan | Utah | 84088 | — |
| Gastroenterology Consultants of Southwest Virginia ( Site 3282) | Roanoke | Virginia | 24014 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 133 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05877547, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jan 12, 2026 · Synced Oct 20, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05877547 live on ClinicalTrials.gov.