ATSN-201 Gene Therapy in RS1-Associated X-linked Retinoschisis
Public ClinicalTrials.gov record NCT05878860. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2/3, Open-Label, Dose Escalation, Dose Expansion and Randomized, Controlled Study to Evaluate the Safety and Efficacy of ATSN-201 Gene Therapy in Subjects With RS1-Associated X-linked Retinoschisis (LIGHTHOUSE)
Study identification
- NCT ID
- NCT05878860
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Atsena Therapeutics Inc.
- Industry
- Enrollment
- 97 participants
Conditions and interventions
Conditions
Interventions
- ATSN-201 Biological
Biological
Eligibility (public fields only)
- Age range
- 6 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Aug 21, 2023
- Primary completion
- Mar 31, 2028
- Completion
- Mar 31, 2033
- Last update posted
- Jul 20, 2026
2023 – 2033
United States locations
- U.S. sites
- 18
- U.S. states
- 13
- U.S. cities
- 17
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Associated Retina Consultants | Phoenix | Arizona | 85020 | Not yet recruiting |
| Shiley Eye Institute | La Jolla | California | 92093 | Not yet recruiting |
| Children's Hospital of Los Angeles | Los Angeles | California | 90027 | Recruiting |
| Stanford University | Palo Alto | California | 94303 | Not yet recruiting |
| UC San Francisco | San Francisco | California | 94158 | Not yet recruiting |
| Bascom Palmer Eye Institute | Miami | Florida | 33136 | Recruiting |
| Massachusetts Eye and Ear | Boston | Massachusetts | 02114 | Recruiting |
| Boston Children's Hospital | Boston | Massachusetts | 02115 | Not yet recruiting |
| University of Michigan | Ann Arbor | Michigan | 48105 | Not yet recruiting |
| Mayo Clinic | Rochester | Minnesota | 55905 | Not yet recruiting |
| Columbia University | New York | New York | 100032 | Not yet recruiting |
| Flaum Eye Institute, University of Rochester | Rochester | New York | 14642 | Not yet recruiting |
| Duke University | Durham | North Carolina | 27710 | Not yet recruiting |
| Oregon Health Sciences University | Portland | Oregon | 97239 | Recruiting |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | Recruiting |
| Retina Foundation of the Southwest | Dallas | Texas | 75231 | Not yet recruiting |
| Moran Eye Center | Salt Lake City | Utah | 84132 | Not yet recruiting |
| University of Wisconsin | Madison | Wisconsin | 53705 | Not yet recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05878860, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 20, 2026 · Synced Jul 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05878860 live on ClinicalTrials.gov.