Study to Evaluate Suprachoroidally Administered CLS-AX in the Treatment of Neovascular Age-Related Macular Degeneration
Public ClinicalTrials.gov record NCT05891548. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
ODYSSEY: A Phase 2b Study of Suprachoroidally Administered CLS-AX in Participants With Neovascular Age-Related Macular Degeneration
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Phase 2b, randomized, double-masked, parallel-group, active-controlled, multicenter, 36-week study designed to assess the safety and efficacy of suprachoroidally administered CLS-AX 1.0 mg with a flexible dosing regimen in participants with neovascular age-related macular degeneration previously treated with intravitreal anti-vascular endothelial growth factor (VEGF) standard of care therapy. Only one eye will be chosen as the study eye.
Study identification
- NCT ID
- NCT05891548
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 60 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- May 31, 2023 (Actual)
- Primary completion
- Aug 20, 2024 (Actual)
- Completion
- Aug 20, 2024 (Actual)
- Last update posted
- Jul 25, 2025
2023 – 2024
United States locations
- U.S. sites
- 32
- U.S. states
- 15
- U.S. cities
- 31
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Associated Retina Consultants | Phoenix | Arizona | 85020 | — |
| Retinal Research Institute, LLC | Phoenix | Arizona | 85053 | — |
| California Retina Consultants | Bakersfield | California | 93309 | — |
| Retina Consultants of Orange County | Fullerton | California | 92835 | — |
| Northern California Retina Vitreous Associates Medical Group, Inc | Mountain View | California | 94040 | — |
| Retina Consultants San Diego | Poway | California | 92064 | — |
| Retinal Consultants of Southern California | Redlands | California | 92374 | — |
| Retinal Consultants Medical Group, Inc. | Sacramento | California | 95825 | — |
| Retina Group of Florida | Fort Lauderdale | Florida | 33308 | — |
| Florida Retina Consultants | Lakeland | Florida | 33805 | — |
| Retina Specialty Institute | Pensacola | Florida | 32503 | — |
| Retina Associates of Florida | Tampa | Florida | 33609 | — |
| Southeast Retina Center | Augusta | Georgia | 30909 | — |
| Georgia Retina, PC | Marietta | Georgia | 30060 | — |
| Illinois Retina Associates | Oak Park | Illinois | 60304 | — |
| Wolfe Eye Clinic | Des Moines | Iowa | 50266 | — |
| Cumberland Valley Retina Consultants | Hagerstown | Maryland | 21740 | — |
| Vitreo-Retinal Associates, PC | Worcester | Massachusetts | 01605 | — |
| Sierra Eye Associates | Reno | Nevada | 89431 | — |
| Envision Ocular LLC | Bloomfield | New Jersey | 07003 | — |
| Western Carolina Retinal Associates P.A. | Asheville | North Carolina | 28803 | — |
| Tennessee Retina PC | Nashville | Tennessee | 37203 | — |
| Retina Research Institute of Texas | Abilene | Texas | 79606 | — |
| Texas Retina Associates - Arlington | Arlington | Texas | 76012 | — |
| Austin Retina | Austin | Texas | 78705 | — |
| Retina Consultants of Texas-Bellairre | Bellaire | Texas | 77401 | — |
| Texas Retina Associates - Dallas | Dallas | Texas | 75231 | — |
| Retina Consultants of Texas - Katy | Katy | Texas | 77494 | — |
| Texas Retina Associates-Plano | Plano | Texas | 75075 | — |
| Retina Consultants of Texas-San Antonio | San Antonio | Texas | 78240 | — |
| Retina Group of Washington | Fairfax | Virginia | 22031 | — |
| Spokane Eye Clinical Research | Spokane | Washington | 99204 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05891548, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 25, 2025 · Synced Oct 18, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05891548 live on ClinicalTrials.gov.