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Terminated Phase 2 Interventional

Study to Evaluate the Efficacy and Safety of Oral CT1812 in Participants With Geographic Atrophy (GA) Secondary to Dry Age-Related Macular Degeneration (AMD).

ClinicalTrials.gov ID: NCT05893537

Public ClinicalTrials.gov record NCT05893537. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 23, 2026, 3:38 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-Masked, Placebo-Controlled, Parallel-Group, Phase 2 Study to Evaluate the Efficacy and Safety of Oral CT1812 in Participants With Geographic Atrophy (GA) Secondary to Dry Age-Related Macular Degeneration (AMD).

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a Phase 2, prospective, multicenter, randomized, double-masked, placebo-controlled 104-week study to assess the efficacy, safety, and tolerability of orally delivered CT1812 compared to placebo in participants with GA associated with dry AMD.

Study identification

NCT ID
NCT05893537
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Cognition Therapeutics
Industry
Enrollment
100 participants

Conditions and interventions

Eligibility (public fields only)

Age range
50 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 16, 2023 (Actual)
Primary completion
Mar 4, 2025 (Actual)
Completion
Mar 28, 2025 (Actual)
Last update posted
Apr 16, 2025

2023 – 2025

United States locations

U.S. sites
19
U.S. states
12
U.S. cities
18
Facility City State ZIP Site status
Phoenix Retina Associates Phoenix Arizona 85050 —
Retinal Consultants Medical Group Sacramento California 95825 —
Bay Area Retina Associates Walnut Creek California 94598 —
Advanced Research Deerfield Beach Florida 33064 —
Rand Eye Institute Deerfield Beach Florida 33064 —
National Ophthalmic Research Institute Fort Myers Florida 11735 —
Center for Retina and Macular Disease Winter Haven Florida 33880 —
Retina Specialists Baltimore Maryland 21204 —
Ophthalmic Consultants of Boston Boston Massachusetts 02114 —
NJ Retina Edison New Jersey 08820 —
Long Island Vitreoretinal Consultants Great Neck New York 11021 —
North Carolina Retina Associates Wake Forest North Carolina 27587 —
Verum Research LLC Eugene Oregon 97401 —
Erie Retina Research, LLC Erie Pennsylvania 16507 —
Tennessee Retina, PC Nashville Tennessee 37203 —
Austin Clinical Research, LLC Austin Texas 78750 —
Star Vision Consultants Burleson Texas 76028 —
Texas Retina Associates Fort Worth Texas 76104 —
Retina Consultants of Texas San Antonio Texas 78240 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05893537, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 16, 2025 · Synced Oct 23, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05893537 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →