Long-term, Open-label Study of SAR447537 (INBRX-101) in Adults With Alpha-1 Antitrypsin Deficiency Emphysema
Public ClinicalTrials.gov record NCT05897424. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Single Arm, Open Label Extension Study, Evaluating the Long-Term Safety and Clinical Efficacy of SAR447537 (INBRX-101) in Adults With Alpha-1 Antitrypsin Deficiency (AATD) Emphysema
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
Phase 2 open label extension study to evaluate SAR447537 (INBRX-101) in adults with AATD emphysema
Study identification
- NCT ID
- NCT05897424
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 185 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 80 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 20, 2024 (Actual)
- Primary completion
- Jun 30, 2028 (Estimated)
- Completion
- Sep 30, 2028 (Estimated)
- Last update posted
- Apr 13, 2026
2024 – 2028
United States locations
- U.S. sites
- 18
- U.S. states
- 16
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| UAB Lung Health Center- Site Number : 105 | Birmingham | Alabama | 35205-2610 | — |
| St Joseph's Hospital and Medical Center- Site Number : 126 | Phoenix | Arizona | 85013-4220 | — |
| David Geffen School of Medicine at UCLA- Site Number : 124 | Los Angeles | California | 90095-3075 | — |
| University of California Davis Medical Center- Site Number : 110 | Sacramento | California | 95817-2201 | — |
| National Jewish Medical and Research Center- Site Number : 123 | Denver | Colorado | 80206-2761 | — |
| Nuvance Health Medical Practices, Pulmonary & Sleep Specialists- Site Number : 119 | Danbury | Connecticut | 06810-5038 | — |
| University of Florida - Gainesville - 1600 SW Archer Rd- Site Number : 101 | Gainesville | Florida | 32610-3003 | — |
| Indiana University- Site Number : 127 | Indianapolis | Indiana | 46202-5128 | — |
| Brigham and Women's Hospital -75 Francis Street- Site Number : 131 | Boston | Massachusetts | 02115-6105 | — |
| University of Minnesota-420 Delaware Str SE- Site Number : 125 | Minneapolis | Minnesota | 55455-0341 | — |
| Hannibal Regional Healthcare System-HRMG-Hannibal- Site Number : 111 | Hannibal | Missouri | 63401-6890 | — |
| Columbia University Irving Medical Center- Site Number : 104 | New York | New York | 10032-3729 | — |
| Oregon Health and Science University- Site Number : 117 | Portland | Oregon | 97239-3011 | — |
| Penn State Health Milton S. Hershey Medical Center- Site Number : 122 | Hershey | Pennsylvania | 17033-2360 | — |
| Temple University Hospital - 3401 N Broad St- Site Number : 130 | Philadelphia | Pennsylvania | 19140-5103 | — |
| Velocity Clinical Research - Spartanburg - PPDS- Site Number : 120 | Spartanburg | South Carolina | 29303-4225 | — |
| Houston Methodist Hospital- Site Number : 113 | Houston | Texas | 77030-2703 | — |
| University of Utah Health Care- Site Number : 106 | Salt Lake City | Utah | 84132-0001 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 22 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05897424, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 13, 2026 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05897424 live on ClinicalTrials.gov.