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Terminated Phase 1 Interventional

Evaluation of IGM-2644 in Adults With Relapsed and/or Refractory Multiple Myeloma

ClinicalTrials.gov ID: NCT05908396

Public ClinicalTrials.gov record NCT05908396. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 5, 2026, 4:25 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

An Open-Label, Multicenter, Phase 1 Study of IGM-2644 in Participants With Relapsed and/or Refractory Multiple Myeloma

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

This is a first in human, phase 1, multicenter, open-label study to determine the safety and tolerability of IGM-2644 as a single agent in participants with relapsed and/or refractory MM, for whom standard therapy does not exist, has proven to be ineffective or intolerable, or is considered inappropriate. Dose escalation and dose expansion cohorts will be enrolled to evaluate safety, preliminary efficacy, and further define a RP2D. The total length of the study, from screening of the first participant to the end of the study, is expected to be approximately 60 months.

Study identification

NCT ID
NCT05908396
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 1
Lead sponsor
IGM Biosciences, Inc.
Industry
Enrollment
4 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Aug 29, 2023 (Actual)
Primary completion
Feb 16, 2024 (Actual)
Completion
Feb 16, 2024 (Actual)
Last update posted
Aug 1, 2024

2023 – 2024

United States locations

U.S. sites
5
U.S. states
5
U.S. cities
5
Facility City State ZIP Site status
City of Hope Duarte California 91010 —
Colorado Blood Cancer Institute Denver Colorado 80218 —
Memorial Sloan Kettering Cancer Center New York New York 10065 —
Tennessee Oncology (SCRI) Nashville Tennessee 37203 —
Fred Hutchinson Cancer Research Center Seattle Washington 98109 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05908396, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 1, 2024 · Synced Oct 5, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT05908396 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →