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Completed Phase 3 Interventional

A Study of Retatrutide (LY3437943) Once Weekly in Participants Who Have Obesity or Overweight and Osteoarthritis of the Knee

ClinicalTrials.gov ID: NCT05931367

Public ClinicalTrials.gov record NCT05931367. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Apr 29, 2026, 8:43 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 3 Study to Investigate the Efficacy and Safety of LY3437943 Once Weekly in Participants Who Have Obesity or Overweight and Osteoarthritis of the Knee: A Randomized, Double-Blind, Placebo-Controlled Trial

Study identification

NCT ID
NCT05931367
Recruitment status
Completed
Study type
Interventional
Phase
Phase 3
Lead sponsor
Eli Lilly and Company
Industry
Enrollment
445 participants

Conditions and interventions

Interventions

  • Placebo Drug
  • Retatrutide Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 31, 2023
Primary completion
Nov 13, 2025
Completion
Nov 13, 2025
Last update posted
Jan 20, 2026

2023 – 2025

United States locations

U.S. sites
13
U.S. states
12
U.S. cities
13
Facility City State ZIP Site status
Arizona Research Center Phoenix Arizona 85053
Artemis Institute for Clinical Research San Diego California 92103
Chase Medical Research, LLC Waterbury Connecticut 06708
Suncoast Research Group Miami Florida 33135
North Georgia Clinical Research Woodstock Georgia 30189
Elite Clinical Trials Blackfoot Idaho 83221
Northwestern University Chicago Illinois 60611
MedVadis Research Corporation Waltham Massachusetts 02451
Great Lakes Research Group, Inc. Bay City Michigan 48706
Clinvest Research LLC Springfield Missouri 65807
Mercy Family Clinic Dallas Texas 75211
Clinical Trials of Texas, Inc. San Antonio Texas 78229
Northwest Clinical Research Center Bellevue Washington 98007

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 36 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05931367, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jan 20, 2026 · Synced Apr 29, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05931367 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →