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Withdrawn Phase 2 Interventional

OT-101 in Combination With Atezolizumab for the Treatment of Metastatic or Recurrent Non-Small Cell Lung Cancer

ClinicalTrials.gov ID: NCT05935774

Public ClinicalTrials.gov record NCT05935774. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 8, 2026, 12:28 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase 2 Trial of TGF-β2 Inhibition (OT-101) With Atezolizumab as Second-Line or Third-Line Therapy for Patients Previously Treated With Immunotherapy (+/- Chemotherapy) With Metastatic Non-Small Cell Lung Cancer (NSCLC)

Study identification

NCT ID
NCT05935774
Recruitment status
Withdrawn
Study type
Interventional
Phase
Phase 2
Lead sponsor
University of Washington
Other
Enrollment
Not listed

Conditions and interventions

Interventions

  • Atezolizumab Biological
  • Biopsy Procedure
  • Biospecimen Collection Procedure
  • Computed Tomography Procedure
  • Electronic Health Record Review Other
  • Magnetic Resonance Imaging Procedure
  • Trabedersen (OT-101) Drug

Biological · Procedure · Other + 1 more

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 30, 2023
Primary completion
Jul 30, 2028
Completion
Jul 30, 2028
Last update posted
Aug 24, 2023

2023 – 2028

United States locations

U.S. sites
1
U.S. states
1
U.S. cities
1
Facility City State ZIP Site status
Fred Hutch/University of Washington Cancer Consortium Seattle Washington 98109

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05935774, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 24, 2023 · Synced May 8, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05935774 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →