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Recruiting Phase 2 Interventional

HPV DNA-Guided Radiotherapy De-intensification of Head and Neck Squamous Cell Carcinoma

ClinicalTrials.gov ID: NCT05962242

Public ClinicalTrials.gov record NCT05962242. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 9, 2026, 10:08 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Circulating Tumor Modified HPV DNA-Guided Radiotherapy De-intensification of the Elective Neck (RaDEN) in Squamous Cell Carcinoma of the Head and Neck

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The study will evaluate the safety and effectiveness of a lower than standard dose of radiation for definitive or adjuvant treatment of head and neck squamous cell carcinomas.

Study identification

NCT ID
NCT05962242
Recruitment status
Recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
University of Virginia
Other
Enrollment
90 participants

Conditions and interventions

Interventions

Radiation

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jun 27, 2024
Primary completion
Oct 31, 2027
Completion
Oct 31, 2029
Last update posted
Feb 4, 2026

2024 – 2029

United States locations

U.S. sites
5
U.S. states
2
U.S. cities
4
Facility City State ZIP Site status
Miami Cancer Institute Miami Florida 33176 Recruiting
University of Virginia Charlottesville Virginia 22908 Recruiting
Eastern Virginia Medical School Norfolk Virginia 23507 Not yet recruiting
Bon Secours Richmond Virginia 23114 Not yet recruiting
Virginia Commonwealth University Richmond Virginia 23284 Recruiting

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT05962242, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Feb 4, 2026 · Synced Sep 9, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT05962242 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →