Shockwave C2+ 2Hz Coronary IVL Catheter in Calcified Coronary Arteries (Disrupt CAD DUO)
Public ClinicalTrials.gov record NCT05966662. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Prospective, Multicenter, Single-Arm IDE Study of the Shockwave Coronary Intravascular Lithotripsy (IVL) System With the Shockwave C2+ 2Hz Coronary IVL Catheter in Calcified Coronary Arteries (Disrupt CAD Duo Study)
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This investigational device exemption (IDE) study is to assess the safety and effectiveness of the Shockwave Coronary Intravascular Lithotripsy (IVL) System with the Shockwave C2+ 2Hz Coronary IVL Catheter to treat de novo, calcified, stenotic, coronary lesions prior to stenting.
Study identification
- NCT ID
- NCT05966662
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 145 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 8, 2023 (Actual)
- Primary completion
- Jan 9, 2025 (Actual)
- Completion
- Dec 19, 2025 (Actual)
- Last update posted
- Feb 24, 2026
2023 – 2025
United States locations
- U.S. sites
- 18
- U.S. states
- 15
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Heart Center Research | Huntsville | Alabama | 35801 | — |
| Scripps Clinic | La Jolla | California | 92121 | — |
| Medstar Washington Hospital Center | Washington D.C. | District of Columbia | 20010 | — |
| Memorial Health | Hollywood | Florida | 33021 | — |
| Wellstar Kennestone Hospital | Marietta | Georgia | 30060 | — |
| Loyola University | Chicago | Illinois | 60153 | — |
| Norton Heart and Vascular Institute | Louisville | Kentucky | 40205 | — |
| Essentia Health St. Mary's Heart & Vascular Center | Duluth | Minnesota | 55805 | — |
| Washington University | St Louis | Missouri | 63110 | — |
| Northwell Health/Lenox Hill | New York | New York | 11030 | — |
| St. Francis Hospital | Roslyn | New York | 11576 | — |
| The Christ Hospital | Cincinnati | Ohio | 45219 | — |
| UPMC Pinnacle Health | Harrisburg | Pennsylvania | 17110 | — |
| WellSpan Health - York | York | Pennsylvania | 17403 | — |
| Baylor Scott and White Research Institute | Dallas | Texas | 75226 | — |
| Methodist Hospital | San Antonio | Texas | 78229 | — |
| Swedish Medical Center | Seattle | Washington | 98122 | — |
| Charleston Area Medical Center | Charleston | West Virginia | 25304 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05966662, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 24, 2026 · Synced Oct 25, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05966662 live on ClinicalTrials.gov.