ClinicalTrials.gov record
Open-Label Extension (OLE) Study to Assess Safety, Efficacy, and Tolerability of Lorundrostat in Subjects With Hypertension
ClinicalTrials.gov ID: NCT05968430
Public ClinicalTrials.gov record NCT05968430. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label Extension Study to Assess the Long-Term Safety, Efficacy, and Tolerability of Lorundrostat in Subjects With Hypertension
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is to evaluate the long-term safety, efficacy and tolerability of lorundrostat (an aldosterone synthase inhibitor) in subjects with hypertension
Study identification
- NCT ID
- NCT05968430
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,076 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 14, 2023 (Actual)
- Primary completion
- Dec 30, 2025 (Actual)
- Completion
- May 2027 (Estimated)
- Last update posted
- Sep 29, 2026
2023 – 2027
United States locations
- U.S. sites
- 128
- U.S. states
- 28
- U.S. cities
- 104
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Accel Research Sites (ARS) - Birmingham Clinical Research Unit | Birmingham | Alabama | 35216 | — |
| G & L Research LLC | Foley | Alabama | 36535 | — |
| Chandler Clinical Trials | Chandler | Arizona | 85224 | — |
| Arizona Kidney | Glendale | Arizona | 85306 | — |
| AKDHC Medical Research Services, AZ | Phoenix | Arizona | 85016 | — |
| Noble Clinical Research | Tucson | Arizona | 85704 | — |
| Del Sol Research Management, LLC | Tucson | Arizona | 85715 | — |
| Entertainment Medical Group, Inc | Beverly Hills | California | 90211 | — |
| CA Institute of Renal Research, CA | Chula Vista | California | 91910 | — |
| Amicis Research Center - Vacaville | Fairfield | California | 94533 | — |
| Amicis Research Center - Granada Hills | Granada Hills | California | 91344 | — |
| Marvel Clinical Research 002, LLC | Huntington Beach | California | 92647 | — |
| University of California San Diego (UCSD) - Altman Clinical and Translational Research Institute (ACTRI) | La Jolla | California | 92037 | — |
| Clinical Trials Research (CTR) - Lincoln | Lincoln | California | 95648 | — |
| Academic Medical Research Institute (AMRI) - Los Angeles | Los Angeles | California | 90022 | — |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | — |
| Amicis Research Center - Mission Hills | Northridge | California | 91324 | — |
| Amicis Research Center-Northridge | Northridge | California | 91324 | — |
| Northridge Clinical Trials | Northridge | California | 91325 | — |
| Pasadena Clinical Trials | Pasadena | California | 91101 | — |
| Empire Clinical Research | Pomona | California | 91767 | — |
| Clinical Trials Research (CTR) - Sacramento | Sacramento | California | 95821 | — |
| Triwest Research Associates | San Diego | California | 92108 | — |
| San Jose Clinical Trials | San Jose | California | 95117 | — |
| Amicis Research Center - Valencia | Valencia | California | 91355 | — |
| Kidney & Hypertension Center - Victorville | Victorville | California | 92395 | — |
| Blue Coast Research Center (BCRC) | Vista | California | 92081 | — |
| Accelerated Enrollment Solutions (AES) -Vista/Synexus (Radiant Research) | Vista | California | 92083 | — |
| Colorado Kidney (Denver) Nephrology | Denver | Colorado | 802320 | — |
| CMR of Greater New Haven | Hamden | Connecticut | 06512 | — |
| Qway Research | Hialeah | Florida | 33010 | — |
| Indago Research and Health Center | Hialeah | Florida | 33012 | — |
| Clinical Neuroscience Solutions, Inc | Jacksonville | Florida | 32256 | — |
| Nuovida Research Center Corp | Miami | Florida | 33186 | — |
| Clinical Neuroscience Solutions, Inc | Orlando | Florida | 32801 | — |
| Nephrology Associates of Central Florida | Orlando | Florida | 32806-6257 | — |
| AES - Orlando | Orlando | Florida | 32806 | — |
| Pines Care Research Center | Pembroke Pines | Florida | 33025 | — |
| Patron Medical - Andres Patron D.O. (Patron Ventures, LLC) | Pembroke Pines | Florida | 33026 | — |
| Progressive Medical Research | Port Orange | Florida | 32127 | — |
| Infigo Clinical Research (Mid Florida) | Sanford | Florida | 32771 | — |
| Clinical Research of West Florida, Inc. | Tampa | Florida | 33606 | — |
| AES The Villages | The Villages | Florida | 32162 | — |
| Palm Beach Diabetes and Endocrine Specialists, PA (PBDES) - West Palm Beach Office) | West Palm Beach | Florida | 33401 | — |
| American Clinical Trials | Acworth | Georgia | 30101 | — |
| Morehouse School of Medicine | Atlanta | Georgia | 30310 | — |
| Coastal Medical | Brunswick | Georgia | 31520 | — |
| Accel Research Sites | Decatur | Georgia | 30030 | — |
| Georgia Clinical Research, LLC | Lawrenceville | Georgia | 30044 | — |
| Alta Pharmaceutical Research Center | Peachtree Corners | Georgia | 30092 | — |
| Elite Clinical Trials | Blackfoot | Idaho | 83221 | — |
| Meridian Family Medicine | Meridian | Idaho | 83646 | — |
| AES Chicago/Synexus Clinical Research | Chicago | Illinois | 60602 | — |
| Eagle Clinical Research | Chicago | Illinois | 60621 | — |
| The University of Chicago Medicine | Chicago | Illinois | 60637 | — |
| Healthcare Research Network - Chicago | Flossmoor | Illinois | 60422 | — |
| Koch Family Medicine, S.C | Morton | Illinois | 61550 | — |
| Southern Illinois School of Medicine | Springfield | Illinois | 62702 | — |
| Hendricks Regional Health Medical Group - Lizton Family Medicine | Brownsburg | Indiana | 46112 | — |
| AES Evansville/Synexus Clinical Research | Evansville | Indiana | 47714 | — |
| ASHA Clinical Research- Munster, LLC | Hammond | Indiana | 46324 | — |
| The Research Group of Lexington, LLC | Lexington | Kentucky | 40503 | — |
| Nephrology Associates of Kentuckiana | Louisville | Kentucky | 40205 | — |
| Alliance for Multispecialty Research, LLC | New Orleans | Louisiana | 70119 | — |
| Northwest Louisiana Nephrology, LLC - Shreveport | Shreveport | Louisiana | 71101 | — |
| Boston Clinical Trials | Boston | Massachusetts | 02131 | — |
| ActiveMed Practices & Research LLC | Methuen | Massachusetts | 01844 | — |
| Hattiesburg Clinic | Petal | Mississippi | 39465 | — |
| Healthcare Research Network-Hazelwood | Hazelwood | Missouri | 63042 | — |
| Clinical Research Consultants (CRC) - Kansas City | Kansas City | Missouri | 64111 | — |
| Quality Clinical Research | Omaha | Nebraska | 68114 | — |
| Henderson Clinical Trials | Henderson | Nevada | 89052 | — |
| Synexus Clinical Research US, Inc. | Henderson | Nevada | 89052 | — |
| Sierra Clinical Research | Las Vegas | Nevada | 89106 | — |
| Oasis Clinical Trials | Las Vegas | Nevada | 89121 | — |
| Las Vegas Clinical Trials | North Las Vegas | Nevada | 89030 | — |
| Renown Regional Medical Center | Reno | Nevada | 89502 | — |
| Albany Medical College | Albany | New York | 12203 | — |
| Erie County Medical Center | Buffalo | New York | 14215 | — |
| AES New York/Synexus Clinical Research | New York | New York | 10027 | — |
| Columbia University | New York | New York | 10032 | — |
| Triad Internal Medicine | Asheboro | North Carolina | 27205 | — |
| East Carolina University (ECU) Physicians - East Carolina Heart Institute - East Carolina University Location | Greenville | North Carolina | 27834 | — |
| Physician's East Endocrinology | Greenville | North Carolina | 27834 | — |
| Carteret Medical Group | Morehead City | North Carolina | 28557 | — |
| Centricity Research New Bern Multispecialty | New Bern | North Carolina | 28562 | — |
| Research Innovations (Elligo Health Research) | Beavercreek | Ohio | 45431 | — |
| Diabetes & Endocrinology Associates of Stark County | Canton | Ohio | 44240 | — |
| Intrepid Research | Cincinnati | Ohio | 45245 | — |
| Cleveland Clinic - Main Campus | Cleveland | Ohio | 44195 | — |
| Arthritis & Osteoarthritis Center of SW Ohio/ dba STAT Research | Vandalia | Ohio | 45377 | — |
| Lynn Institute of Norman (LION Research) | Norman | Oklahoma | 73072 | — |
| Willamette Valley Clinical Studies | Eugene | Oregon | 97404 | — |
| AMS Cardiology (Elligo) | Horsham | Pennsylvania | 19044 | — |
| University of Pennsylvania | Philadelphia | Pennsylvania | 19104 | — |
| Preferred Primary Care Physicians | Pittsburgh | Pennsylvania | 15236 | — |
| Accelerated Enrollment Solutions (AES) - Anderson | Anderson | South Carolina | 29621 | — |
| Wake Research - Notus Clinical Trials, LLC | Charleston | South Carolina | 29414 | — |
| Coastal Carolina Research Center | North Charleston | South Carolina | 29405 | — |
| Chattanooga Medical Research | Chattanooga | Tennessee | 37412 | — |
| AMR - Knoxville | Knoxville | Tennessee | 37920 | — |
| Clinical Neuroscience Solutions, Inc | Memphis | Tennessee | 38119 | — |
| Lifedoc Research | Memphis | Tennessee | 38119 | — |
| Vanderbilt University Medical Center (VUMC) | Nashville | Tennessee | 37232 | — |
| Punzi Medical Center | Carrollton | Texas | 75006 | — |
| AES - Dallas Fort Worth | Dallas | Texas | 75234 | — |
| David Turbay, MD, PLLC (Elligo Health Research) | El Paso | Texas | 79905 | — |
| Synergy Groups Medical - Bissonet Site | Houston | Texas | 77036 | — |
| Juno Research, LLC | Houston | Texas | 77054 | — |
| Gulf Coast Clinical Research | Houston | Texas | 77070 | — |
| Medical Colleagues of Texas, LLP (Elligo Health Research) | Katy | Texas | 77450 | — |
| R & H Clinical Research | Katy | Texas | 77450 | — |
| Gamma Medical Research, Inc | McAllen | Texas | 78503 | — |
| Office of Audrey L. Jones, DO | McAllen | Texas | 78503 | — |
| PRX Research - Mesquite | Mesquite | Texas | 75149 | — |
| Synergy Groups Medical - Missouri City | Missouri City | Texas | 77459 | — |
| ACRC Trials - Legacy Medical Village Location | Plano | Texas | 75024 | — |
| Clinical Investigations of Texas (CIT) | Plano | Texas | 75075 | — |
| ACRC Trials - Legacy Medical Village | Plano | Texas | 75093 | — |
| Sun Research Institute (SRI) - San Antonio | San Antonio | Texas | 78215 | — |
| San Antonio ClinicalTrials | San Antonio | Texas | 78240 | — |
| Discovery Clinical Trials | San Antonio | Texas | 78258 | — |
| Sugar Lakes Family Practice (Elligo Health Research) | Sugar Land | Texas | 77479 | — |
| The University of Utah | Salt Lake City | Utah | 84132 | — |
| Velocity Clinical Research | West Jordan | Utah | 84088 | — |
| Burke Internal Medicine | Burke | Virginia | 22015 | — |
| Eastern VA Medical School | Norfolk | Virginia | 23501 | — |
| Office of Ramon Mendez | Woodbridge | Virginia | 22192 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 49 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05968430, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 29, 2026 · Synced Oct 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05968430 live on ClinicalTrials.gov.