A Study to Evaluate the Safety and Immunogenicity of mRNA-1975 and mRNA-1982 Against Lyme Disease in Participants 18 Through 70 Years of Age
Public ClinicalTrials.gov record NCT05975099. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 1/2, Randomized, Observer-blind, Placebo-controlled, Dose-ranging Study to Evaluate the Safety and Immunogenicity of Heptavalent mRNA-1975 (SR1-7) and Monovalent mRNA-1982 (SR1) in Parallel Against Lyme Disease in Healthy Participants 18 Through 70 Years of Age
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the safety and immunogenicity in parallel of heptavalent mRNA-1975 and monovalent mRNA-1982 against Lyme disease in healthy adult participants.
Study identification
- NCT ID
- NCT05975099
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 1, Phase 2
- Enrollment
- 807 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 70 Years
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 26, 2023 (Actual)
- Primary completion
- May 30, 2025 (Actual)
- Completion
- May 30, 2025 (Actual)
- Last update posted
- Jul 30, 2026
2023 – 2025
United States locations
- U.S. sites
- 20
- U.S. states
- 15
- U.S. cities
- 20
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Clinical Research Consulting, LLC | Milford | Connecticut | 06460 | — |
| Stamford Therapeutics Consortium | Stamford | Connecticut | 06905 | — |
| Chase Medical Research, LLC | Waterbury | Connecticut | 06708 | — |
| Encore Research Group-Jacksonville Center for Clinical Research | Jacksonville | Florida | 32216 | — |
| University Clinical Research-DeLand, LLC d/b/a Accel Research Sites | Lake Mary | Florida | 32746 | — |
| Clinical Research Atlanta, headlands LLC | Stockbridge | Georgia | 30281 | — |
| Johnson County Clin-Trials, Inc. (JCCT) | Lenexa | Kansas | 66219 | — |
| Centennial Medical Group | Columbia | Maryland | 21045 | — |
| Advanced Primary and Geriatric Care | Rockville | Maryland | 20850 | — |
| DM Clinical Research - Brookline | Brookline | Massachusetts | 02445 | — |
| Clinical Research Institute, Inc. | Minneapolis | Minnesota | 55402 | — |
| Meridian Clinical Research - Omaha | Omaha | Nebraska | 68134 | — |
| ActivMed Research LLC | Newington | New Hampshire | 03801 | — |
| Rochester Clinical Research, Inc. | Rochester | New York | 14609 | — |
| Lynn Health Science Institute | Oklahoma City | Oklahoma | 73112 | — |
| Hatboro Medical Associates/CCT Research | Hatboro | Pennsylvania | 19040 | — |
| Velocity Clinical Research Providence | Providence | Rhode Island | 02886 | — |
| Benchmark Research | Fort Worth | Texas | 76135 | — |
| DM Clinical Research | Tomball | Texas | 77375 | — |
| Charlottesville Medical Research Center, LLC | Charlottesville | Virginia | 22911 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05975099, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 30, 2026 · Synced Oct 31, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05975099 live on ClinicalTrials.gov.