A Study to Investigate the Safety and Efficacy of KER-012 in Combination With Background Therapy in Adult Participants With Pulmonary Arterial Hypertension (PAH) (TROPOS Study).
Public ClinicalTrials.gov record NCT05975905. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Phase 2, Double-blind, Placebo-controlled Study to Investigate the Safety and Efficacy of KER-012 in Combination With Background Therapy in Adult Participants With Pulmonary Arterial Hypertension (TROPOS Study)
Study identification
- NCT ID
- NCT05975905
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Keros Therapeutics, Inc.
- Industry
- Enrollment
- 113 participants
Conditions and interventions
Conditions
Interventions
- Dose A KER-012 Biological
- Dose B KER-012 Biological
- Dose C KER-012 Biological
- Placebo for 24 Weeks followed by Dose B KER-012 for 72 weeks Biological
Biological
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 16, 2023
- Primary completion
- Mar 4, 2025
- Completion
- Mar 10, 2025
- Last update posted
- Jul 1, 2026
2023 – 2025
United States locations
- U.S. sites
- 16
- U.S. states
- 12
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| TROPOS Study Site 111 | Scottsdale | Arizona | 85258 | — |
| TROPOS Study Site 107 | Tucson | Arizona | 85719 | — |
| Site PI TROPOS Study Site 104 | Stanford | California | 94305 | — |
| TROPOS Study Site 105 | Torrance | California | 90502 | — |
| TROPOS Study Site 108 | Jacksonville | Florida | 32224 | — |
| TROPOS Study Site 100 | Kansas City | Kansas | 66160 | — |
| TROPOS Study Site 110 | Louisville | Kentucky | 40202 | — |
| TROPOS Study Site 103 | Boston | Massachusetts | 02111 | — |
| TROPOS Study Site 109 | Boston | Massachusetts | 02115 | — |
| TROPOS Study Site 101 | Ann Arbor | Michigan | 481091 | — |
| TROPOS Study Site 115 | St Louis | Missouri | 63110 | — |
| TROPOS Study Site 114 | Albuquerque | New Mexico | 87106 | — |
| TROPOS Study Site 113 | Cincinnati | Ohio | 45221 | — |
| TROPOS Study Site 106 | Charleston | South Carolina | 29425 | — |
| TROPOS Study Site 112 | Dallas | Texas | 75390 | — |
| TROPOS Study Site 102 | Houston | Texas | 77030 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 39 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05975905, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 1, 2026 · Synced Jul 24, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05975905 live on ClinicalTrials.gov.