Real-World Effectiveness of Dupilumab in Patients With Prurigo Nodularis: An Observational Study
Public ClinicalTrials.gov record NCT05991323. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Prospective Observational Study of Patients Receiving Dupilumab for Prurigo Nodularis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This study is a prospective, multinational, observational investigation designed to elucidate the real-world effectiveness and treatment patterns of dupilumab therapy in adult patients diagnosed with prurigo nodularis (PN). The primary objective of this study is to comprehensively characterize the real-world usage of dupilumab for the management of PN. In addition to this, the study aims to achieve several secondary objectives, including a detailed assessment of the medical history, socio-demographic and disease characteristics of dupilumab-treated PN patients, as well as the evaluation of the long-term real-world effectiveness of dupilumab therapy for PN.
Study identification
- NCT ID
- NCT05991323
- Recruitment status
- Active, not recruiting
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 100 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 11, 2023
- Primary completion
- Sep 21, 2026
- Completion
- Sep 21, 2026
- Last update posted
- Sep 15, 2025
2023 – 2026
United States locations
- U.S. sites
- 23
- U.S. states
- 13
- U.S. cities
- 21
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Medical Dermatology Specialists Site Number : 8400005 | Phoenix | Arizona | 85006-2754 | — |
| Saguaro Dermatology Associates, LLC - Probity - PPDS- Site Number : 8400024 | Phoenix | Arizona | 85008-3884 | — |
| Center for Dermatology Clinical Research- Site Number : 8400002 | Fremont | California | 94538 | — |
| Halcyon Dermatology- Site Number : 8400023 | Laguna Hills | California | 92653 | — |
| Mission Dermatology - Rancho Santa Margarita- Site Number : 8400015 | Rancho Santa Margarita | California | 92688-3623 | — |
| Golden State Dermatology- Site Number : 8400014 | Walnut Creek | California | 94598-3335 | — |
| Total Vein And Skin, LLC- Site Number : 8400019 | Boynton Beach | Florida | 33437-3782 | — |
| GSI Clinical Research- Site Number : 8400017 | Margate | Florida | 33063-7011 | — |
| Allergy Center at Brookstone Research - Centricity Research - PPDS- Site Number : 8400025 | Columbus | Georgia | 31904 | — |
| Dawes Fretzin Clinical Research Group-7910 N Shadeland Ave- Site Number : 8400003 | Indianapolis | Indiana | 46250-2041 | — |
| Oakland Hills Dermatology - 3400 Auburn Rd- Site Number : 8400007 | Auburn Hills | Michigan | 48326-3396 | — |
| Derm Institute of Western Michigan- Site Number : 8400034 | Caledonia | Michigan | 49316-7478 | — |
| Dermatology Associates Western Michigan- Site Number : 8400033 | Grand Rapids | Michigan | 49546-6204 | — |
| U.S. Dermatology Partners Lee's Summit- Site Number : 8400016 | Lee's Summit | Missouri | 64064 | — |
| University of Nebraska - Lauritzen Outpatient Center- Site Number : 8400029 | Omaha | Nebraska | 68105-1026 | — |
| Vivida Dermatology - Flamingo- Site Number : 8400013 | Las Vegas | Nevada | 89119 | — |
| Las Vegas Dermatology- Site Number : 8400027 | Las Vegas | Nevada | 89144-0518 | — |
| Duke Dermatology Clinic- Site Number : 8400026 | Durham | North Carolina | 27710-4000 | — |
| Medical University of South Carolina (MUSC) - PPDS- Site Number : 8400001 | Charleston | South Carolina | 29425-8903 | — |
| North Texas Center for Clinical Research- Site Number : 8400012 | Frisco | Texas | 75034 | — |
| U.S. Dermatology Partners Longview- Site Number : 8400032 | Longview | Texas | 75601 | — |
| Texas Tech University Health Sciences Center-125 W Hague Rd- Site Number : 8400010 | Lubbock | Texas | 79430-0002 | — |
| West Virginia Research Institute- Site Number : 8400030 | Morgantown | West Virginia | 26505-1873 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 26 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05991323, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 15, 2025 · Synced Sep 8, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT05991323 live on ClinicalTrials.gov.