Amulet™ ADVANCE LAA
Public ClinicalTrials.gov record NCT05997446. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Real-World Study to Observe Outcomes of Patients Undergoing Closure With the Amplatzer™ Amulet™ Left Atrial Appendage Occluder
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a prospective, multicenter, observational study intended to characterize real-world outcomes on the commercially available Amulet device in the United States. Over 600 subjects have been enrolled at 16 US clinical sites. Subjects will be followed through 24 months in accordance with each site's standard care practices.
Study identification
- NCT ID
- NCT05997446
- Recruitment status
- Active, not recruiting
- Study type
- Observational
- Phase
- Not listed
- Enrollment
- 610 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jul 12, 2023 (Actual)
- Primary completion
- Jun 2027 (Estimated)
- Completion
- Jun 2027 (Estimated)
- Last update posted
- Oct 1, 2025
2023 – 2027
United States locations
- U.S. sites
- 16
- U.S. states
- 12
- U.S. cities
- 16
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Arizona Arrhythmia Research | Phoenix | Arizona | 85016 | — |
| Arkansas Heart Hospital | Little Rock | Arkansas | 72211 | — |
| Baptist Medical Center | Jacksonville | Florida | 32207 | — |
| Usman R. Siddiqui, MD | Winter Park | Florida | 32792 | — |
| PERC - O'Fallon | O'Fallon | Illinois | 62269 | — |
| Kansas City Cardiac Arrhythmia Research Foundation | Overland Park | Kansas | 66211 | — |
| Cardiovascular Research Institute of Kansas | Wichita | Kansas | 67226 | — |
| Providence Hospital | Southfield | Michigan | 48075 | — |
| Bryan Heart | Lincoln | Nebraska | 68506 | — |
| CHI Health Creighton University Medical Center-Bergan Mercy | Omaha | Nebraska | 68124 | — |
| New York University Hospital | New York | New York | 10016 | — |
| Pinnacle Health System | Mechanicsburg | Pennsylvania | 17150 | — |
| Trident Medical Center | Charleston | South Carolina | 29406 | — |
| Vanderbilt Heart & Vascular Institute | Nashville | Tennessee | 37232 | — |
| Baylor All Saints Medical Center at Fort Worth | Fort Worth | Texas | 76104 | — |
| Heart Rhythm Associates | Shenandoah | Texas | 77380 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT05997446, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 1, 2025 · Synced Oct 18, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT05997446 live on ClinicalTrials.gov.