A Phase 1, First in Human Study of TORL-4-500 in Patients With Advanced Cancer
Public ClinicalTrials.gov record NCT06005740. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
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Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of TORL-4-500 in patients with advanced cancer. For Part 1, any advanced or metastatic solid tumor malignancy will be evaluated including, for example, adrenocortical carcinoma (ACC).
Study identification
- NCT ID
- NCT06005740
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 70 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 4, 2023 (Actual)
- Primary completion
- Mar 29, 2027 (Estimated)
- Completion
- May 31, 2027 (Estimated)
- Last update posted
- Sep 21, 2026
2023 – 2027
United States locations
- U.S. sites
- 8
- U.S. states
- 5
- U.S. cities
- 8
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic Phoenix | Phoenix | Arizona | 85054 | — |
| Providence Medical Foundation | Fullerton | California | 92835 | — |
| UCLA - JCCC Clinical Research Unit | Los Angeles | California | 90095 | — |
| Torrance Memorial Physician Network | Torrance | California | 90505 | — |
| Mayo Clinic Jacksonville | Jacksonville | Florida | 32224 | — |
| Florida Cancer Specialists Lake Nona Drug Development Unit | Orlando | Florida | 32827 | — |
| Mayo Clinic Rochester | Rochester | Minnesota | 55905 | — |
| Virginia Cancer Specialists | Lexington | Virginia | 22031 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06005740, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 21, 2026 · Synced Nov 6, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06005740 live on ClinicalTrials.gov.