A Phase 1, First in Human Study of TORL-4-500 in Patients With Advanced Cancer
Public ClinicalTrials.gov record NCT06005740. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This first-in-human study will evaluate the safety, tolerability, pharmacokinetics, and antitumor activity of TORL-4-500 in patients with advanced cancer. For Part 1, any advanced or metastatic solid tumor malignancy will be evaluated including, for example, adrenocortical carcinoma (ACC).
Study identification
- NCT ID
- NCT06005740
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 1
- Enrollment
- 70 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 3, 2023
- Primary completion
- Mar 28, 2027
- Completion
- May 30, 2027
- Last update posted
- Sep 20, 2026
2023 – 2027
United States locations
- U.S. sites
- 8
- U.S. states
- 5
- U.S. cities
- 8
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Mayo Clinic Phoenix | Phoenix | Arizona | 85054 | — |
| Providence Medical Foundation | Fullerton | California | 92835 | — |
| UCLA - JCCC Clinical Research Unit | Los Angeles | California | 90095 | — |
| Torrance Memorial Physician Network | Torrance | California | 90505 | — |
| Mayo Clinic Jacksonville | Jacksonville | Florida | 32224 | — |
| Florida Cancer Specialists Lake Nona Drug Development Unit | Orlando | Florida | 32827 | — |
| Mayo Clinic Rochester | Rochester | Minnesota | 55905 | — |
| Virginia Cancer Specialists | Lexington | Virginia | 22031 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 2 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06005740, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 20, 2026 · Synced Sep 21, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06005740 live on ClinicalTrials.gov.