ClinicalTrials.gov record
Study to Assess the Safety and Effectiveness of NMRA-335140-501
ClinicalTrials.gov ID: NCT06029439
Public ClinicalTrials.gov record NCT06029439. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Long-term Study to Assess the Safety and Effectiveness of NMRA-335140 in Participants With Major Depressive Disorder
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a 52-week open-label extension (OLE) study that will evaluate the safety, tolerability, and effectiveness of NMRA-335140 in participants with major depressive disorder (MDD). Participants who completed a parent study investigating the efficacy and safety of NMRA-335140 as a treatment for MDD (ie, NMRA-335140-301, NMRA-335140-302, or NMRA-335140-303), and complete the 6 weeks double-blind treatment, provide informed consent, and meet eligibility criteria, may enter this extension study.
Study identification
- NCT ID
- NCT06029439
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,000 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 9, 2023
- Primary completion
- May 31, 2027
- Completion
- May 31, 2027
- Last update posted
- Jun 8, 2026
2023 – 2027
United States locations
- U.S. sites
- 126
- U.S. states
- 27
- U.S. cities
- 97
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Neumora Investigator site | Huntsville | Alabama | 35801 | — |
| Neumora Investigator Site | Phoenix | Arizona | 85012 | — |
| Neumora Investigator Site | Bentonville | Arkansas | 72712 | — |
| Neumora Investigator Site #1 | Little Rock | Arkansas | 72211 | — |
| Neumora Investigator site | Little Rock | Arkansas | 72211 | — |
| Neumora Investigator Site | Rogers | Arkansas | 72758 | — |
| Neumora Investigator site | Bellflower | California | 90706 | — |
| Neumora Investigator Site | Cerritos | California | 90703 | — |
| Neumora Investigator Site | Encino | California | 91316 | — |
| Neumora Investigator Site | Garden Grove | California | 92845 | — |
| Neumora Investigator Site | Glendale | California | 91206 | — |
| Neumora Investigator Site | Imperial | California | 92251 | — |
| Neumora Investigator Site | Irvine | California | 92614 | — |
| Neumora Investigator Site | Lafayette | California | 94549 | — |
| Neumora Investigator Site #1 | Long Beach | California | 90807 | — |
| Neumora Investigator site | Long Beach | California | 90807 | — |
| Neumora Investigator Site | Los Angeles | California | 90015 | — |
| Neumora Investigator Site | Newport Beach | California | 92660 | — |
| Neumora Investigator Site | Oceanside | California | 92056 | — |
| Neumora Investigator Site #1 | Orange | California | 92868 | — |
| Neumora Investigator Site | Orange | California | 92868 | — |
| Neumora Investigator Site | Riverside | California | 92506 | — |
| Neumora Investigator Site | San Diego | California | 92103 | — |
| Neumora Investigator Site | San Francisco | California | 94107 | — |
| Neumora Investigator Site | San Jose | California | 95124 | — |
| Neumora Investigator Site | Santa Ana | California | 92704 | — |
| Neumora Investigator Site | Sherman Oaks | California | 91403 | — |
| Neumora Investigator Site | Temecula | California | 92591 | — |
| Neumora Investigator Site | Torrance | California | 90504 | — |
| Neumora Investigator Site | Colorado Springs | Colorado | 80910 | — |
| Neumora Investigator Site | New Haven | Connecticut | 06520 | — |
| Neumora Investigator Site | Norwalk | Connecticut | 06851 | — |
| Neumora Investigator Site | Bradenton | Florida | 34205 | — |
| Neumora Investigator Site | Brandon | Florida | 33511 | — |
| Neumora Investigator Site | Gainesville | Florida | 32607 | — |
| Neumora Investigator Site | Hallandale | Florida | 33009 | — |
| Neumora Investigator Site | Hialeah | Florida | 33012 | — |
| Neumora Investigator Site | Hialeah | Florida | 33016 | — |
| Neumora Investigator Site | Hollywood | Florida | 33024 | — |
| Neumora Investigator Site | Jacksonville | Florida | 32256 | — |
| Neumora Investigator Site | Lauderhill | Florida | 33319 | — |
| Neumora Investigator Site | Maitland | Florida | 32751 | — |
| Neumora Investigator Site | Miami | Florida | 33122 | — |
| Neumora Investigator Site | Miami | Florida | 33126 | — |
| Neumora Investigator Site | Miami | Florida | 33133 | — |
| Neumora Investigator Site | Miami | Florida | 33137 | — |
| Neumora Investigator Site | Miami | Florida | 33143 | — |
| Neumora Investigator Site | Miami | Florida | 33165 | — |
| Neumora Investigator Site | Miami | Florida | 33174 | — |
| Neumora Investigator site | Miami | Florida | 33183 | — |
| Neumora Investigator Site | Miami Beach | Florida | 33140 | — |
| Neumora Investigator site | Miami Lakes | Florida | 33014 | — |
| Neumora Investigator Site #1 | Miami Lakes | Florida | 33016 | — |
| Neumora Investigator Site #2 | Miami Lakes | Florida | 33016 | — |
| Neumora Investigator Site | Miami Springs | Florida | 33166 | — |
| Neumora Investigator Site #1 | Orlando | Florida | 32801 | — |
| Neumora Investigator site | Orlando | Florida | 32801 | — |
| Neumora Investigator Site | Orlando | Florida | 32803 | — |
| Neumora Investigator Site | Orlando | Florida | 32807 | — |
| Neumora Investigator Site | Pembroke Pines | Florida | 33024 | — |
| Neumora Investigator Site #1 | Pompano Beach | Florida | 33060 | — |
| Neumora Investigator Site | Pompano Beach | Florida | 33060 | — |
| Neumora Investigator Site | Saint Augustine | Florida | 32086 | — |
| Neumora Investigator Site | Tampa | Florida | 33607 | — |
| Neumora Investigator Site #1 | Tampa | Florida | 33613 | — |
| Neumora Investigator Site | Tampa | Florida | 33613 | — |
| Neumora Investigator Site | Atlanta | Georgia | 30318 | — |
| Neumora Investigator Site #1 | Atlanta | Georgia | 30328 | — |
| Neumora Investigator Site | Atlanta | Georgia | 30328 | — |
| Neumora Investigator Site | Atlanta | Georgia | 30338 | — |
| Neumora Investigator Site | Decatur | Georgia | 30030 | — |
| Neumora Investigator Site | Marietta | Georgia | 30060 | — |
| Neumora Investigator Site | Savannah | Georgia | 31405 | — |
| Neumora Investigator Site | Chicago | Illinois | 60634 | — |
| Neumora Investigator Site | Warrenville | Illinois | 60555 | — |
| Neumora Investigator Site | Marrero | Louisiana | 70072 | — |
| Neumora Investigator Site | New Orleans | Louisiana | 70115 | — |
| Neumora Investigator Site | Baltimore | Maryland | 21208 | — |
| Neumora Investigator site | Towson | Maryland | 21204 | — |
| Neumora Investigator Site | Boston | Massachusetts | 02116 | — |
| Neumora Investigator Site | Boston | Massachusetts | 02131 | — |
| Neumora Investigator site | Methuen | Massachusetts | 01844 | — |
| Neumora Investigator site | Springfield | Massachusetts | 01103 | — |
| Neumora Investigator Site | Watertown | Massachusetts | 02472 | — |
| Neumora Investigator site | Bloomfield Township | Michigan | 48302 | — |
| Neumora Investigator Site | Mankato | Minnesota | 56001 | — |
| Neumora Investigator Site | Flowood | Mississippi | 39232 | — |
| Neumora Investigator Site | Saint Charles | Missouri | 63304 | — |
| Neumora Investigator Site | St Louis | Missouri | 63141 | — |
| Neumora Investigator Site | Las Vegas | Nevada | 89102 | — |
| Neumora Investigator Site | Berlin | New Jersey | 08009 | — |
| Neumora Investigator site | Princeton | New Jersey | 08540 | — |
| Neumora Investigator Site | Toms River | New Jersey | 08755 | — |
| Neumora Investigator Site | Albuquerque | New Mexico | 87109 | — |
| Neumora Investigator Site | Brooklyn | New York | 11224 | — |
| Neumora Investigator Site | Buffalo | New York | 14215 | — |
| Neumora Investigator Site | Cedarhurst | New York | 11516 | — |
| Neumora Investigator Site | Inwood | New York | 11096 | — |
| Neumora Investigator Site | New York | New York | 10017 | — |
| Neumora Investigator Site | New York | New York | 10029 | — |
| Neumora Investigator Site | New York | New York | 10036 | — |
| Neumora Investigator Site | Staten Island | New York | 10310 | — |
| Neumora Investigator Site | Staten Island | New York | 10314 | — |
| Neumora Investigator Site | The Bronx | New York | 10461 | — |
| Neumora Investigator Site | Charlotte | North Carolina | 28211 | — |
| Neumora Investigator Site | Monroe | North Carolina | 28112 | — |
| Neumora Investigator Site | Columbus | Ohio | 43210 | — |
| Neumora Investigator Site | Dayton | Ohio | 45417 | — |
| Neumora Investigator Site | North Canton | Ohio | 44720 | — |
| Neumora Investigator Site | Edmond | Oklahoma | 73013 | — |
| Neumora Investigator Site | Oklahoma City | Oklahoma | 73118 | — |
| Neumora Investigator Site | Allentown | Pennsylvania | 18104 | — |
| Neumora Investigator Site | Media | Pennsylvania | 19063 | — |
| Neumora Investigator Site | Philadelphia | Pennsylvania | 19104 | — |
| Neumora Investigator Site | Memphis | Tennessee | 38119 | — |
| Neumora Investigator Site | Austin | Texas | 78737 | — |
| Neumora Investigator site | Austin | Texas | 78759 | — |
| Neumora Investigator Site | Dallas | Texas | 75243 | — |
| Neumora Investigator Site | DeSoto | Texas | 75115 | — |
| Neumora Investigator Site | Fort Worth | Texas | 76104 | — |
| Neumora Investigator Site #1 | Houston | Texas | 77030 | — |
| Neumora Investigator Site | Houston | Texas | 77030 | — |
| Neumora Investigator Site | Houston | Texas | 77090 | — |
| Neumora Investigator Site | Wichita Falls | Texas | 76309 | — |
| Neumora Investigator Site | Bellevue | Washington | 98007 | — |
| Neumora Investigator Site #1 | Everett | Washington | 98201 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 52 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06029439, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 8, 2026 · Synced Sep 11, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06029439 live on ClinicalTrials.gov.