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Active, not recruiting Phase 2 Interventional

A US Study to Evaluate Transarterial Radioembolization (TARE) in Combination With Durvalumab and Bevacizumab Therapy in People With Unresectable Hepatocellular Carcinoma Amenable to TARE

ClinicalTrials.gov ID: NCT06040099

Public ClinicalTrials.gov record NCT06040099. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 25, 2026, 8:07 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

Phase II Single-Arm Study of Durvalumab and Bevacizumab Following Transarterial Radioembolization Using Yttrium-90 Glass Microspheres (TheraSphere™) in Unresectable Hepatocellular Carcinoma Amenable to Locoregional Therapy

Study identification

NCT ID
NCT06040099
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
AstraZeneca
Industry
Enrollment
58 participants

Conditions and interventions

Interventions

  • Durvalumab Drug
  • Bevacizumab Drug
  • Transarterial Radioembolization (TARE) Procedure

Drug · Procedure

Eligibility (public fields only)

Age range
18 Years to 130 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Feb 12, 2024
Primary completion
Jun 30, 2026
Completion
Jun 30, 2026
Last update posted
Mar 18, 2026

2024 – 2026

United States locations

U.S. sites
21
U.S. states
17
U.S. cities
19
Facility City State ZIP Site status
Research Site Aurora Colorado 80045
Research Site Gainesville Florida 32608
Research Site Orlando Florida 32804
Research Site Atlanta Georgia 30322
Research Site Atlanta Georgia 30342
Research Site Chicago Illinois 60611
Research Site Boston Massachusetts 02118
Research Site Detroit Michigan 48201
Research Site St Louis Missouri 63110
Research Site Trenton New Jersey 08690
Research Site Buffalo New York 14263
Research Site New York New York 10029
Research Site Chapel Hill North Carolina 27599
Research Site Columbus Ohio 43210
Research Site Portland Oregon 97239
Research Site Philadelphia Pennsylvania 19107
Research Site Houston Texas 77030
Research Site Charlottesville Virginia 22908
Research Site Seattle Washington 98195
Research Site Milwaukee Wisconsin 53215
Research Site Milwaukee Wisconsin 53226

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06040099, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Mar 18, 2026 · Synced Jun 25, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06040099 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →