A Study to Evaluate the Safety and Immune Response of mRNA-1345, a Vaccine Targeting Respiratory Syncytial Virus (RSV), When Co-administered With a Fluzone HD, in Adults ≥65 Years of Age
Public ClinicalTrials.gov record NCT06060457. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Observer-Blind Study to Evaluate Safety, Tolerability, and Immunogenicity of mRNA-1345, an mRNA Vaccine Targeting Respiratory Syncytial Virus, When Coadministered With a High-Dose, Quadrivalent Seasonal Influenza Vaccine in Adults ≥65 Years of Age
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this study is to evaluate the safety and immunogenicity of mRNA-1345 RSV vaccine when coadministered with a high dose (HD) quadrivalent seasonal influenza vaccine (Fluzone HD) in adults ≥65 years of age. The study will examine the impact of Fluzone HD on the immune response to mRNA-1345 against RSV-A and RSV-B, as well as the impact of mRNA-1345 on the immune response to Fluzone HD against 4 vaccine-matched Influenza A and B strains.
Study identification
- NCT ID
- NCT06060457
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,900 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 65 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Sep 25, 2023 (Actual)
- Primary completion
- Jun 7, 2024 (Actual)
- Completion
- Jun 7, 2024 (Actual)
- Last update posted
- Jul 30, 2025
2023 – 2024
United States locations
- U.S. sites
- 34
- U.S. states
- 19
- U.S. cities
- 32
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Scottsdale Clinical Trials | Scottsdale | Arizona | 85258 | — |
| Headlands Research, Inc. | Scottsdale | Arizona | 85260 | — |
| West Coast Research LLC | Dublin | California | 94568 | — |
| Artemis Institute for Clinical Research | Riverside | California | 92503 | — |
| Peninsula Research Associates (PRA) | Rolling Hills Estates | California | 90274 | — |
| Acclaim Clinical Research | San Diego | California | 92120 | — |
| Neoclinical Research | Hialeah | Florida | 33016 | — |
| Health Awareness INC | Jupiter | Florida | 33458 | — |
| South Florida Research Center, Inc. | Miami | Florida | 33135 | — |
| Suncoast Research Associates, LLC | Miami | Florida | 33173 | — |
| Headlands Research - Orlando | Orlando | Florida | 32819 | — |
| New Tampa Health, Inc | Tampa | Florida | 33603 | — |
| Clinical Research Atlanta/Headlands | Stockbridge | Georgia | 30281 | — |
| Bingham Memorial Hospital | Blackfoot | Idaho | 83221 | — |
| DM Clinical Research- River Forest | River Forest | Illinois | 60305 | — |
| Velocity Clinical Research-Baton Rouge | Baton Rouge | Louisiana | 70809 | — |
| DelRicht Research @ Neighborhood Health | Prairieville | Louisiana | 70769 | — |
| DM Clinical Research - Brookline | Brookline | Massachusetts | 02445 | — |
| DM Clinical Research - Southfield | Southfield | Michigan | 48076 | — |
| Delricht Research at Gulfport Memorial | Gulfport | Mississippi | 39503 | — |
| Delricht Research | Springfield | Missouri | 65807 | — |
| Be Well Clinical Studies, LLC | Lincoln | Nebraska | 68516 | — |
| Velocity Clinical Research-Norfolk | Norfolk | Nebraska | 68701 | — |
| Trial Management Associates, LLC | Wilmington | North Carolina | 28403 | — |
| Synexus AES - Akron | Akron | Ohio | 44311 | — |
| Centricity Research | Columbus | Ohio | 43213 | — |
| Delricht Tate | Tulsa | Oklahoma | 74133 | — |
| DM Clinical Research - Philadelphia | Philadelphia | Pennsylvania | 19107 | — |
| Spartanburg Medical Research | Spartanburg | South Carolina | 29303 | — |
| Delricht Moyer | Hendersonville | Tennessee | 37075 | — |
| DM Clinical Research - Houston | Houston | Texas | 77065 | — |
| DELRICHT RESEARCH at ZOMNIR FAMILY MEDICINE | McKinney | Texas | 75070 | — |
| Javara Inc. /Privia Medical Group Gulf Coast, PLLC | Sugar Land | Texas | 77054 | — |
| DM Clinical Research | Tomball | Texas | 77375 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06060457, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 30, 2025 · Synced Oct 26, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06060457 live on ClinicalTrials.gov.