Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome
Public ClinicalTrials.gov record NCT06066502. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
PREcision VENTilation to Attenuate Ventilator-Induced Lung Injury: A Phase 3 Multicenter Randomized Clinical Trial
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The goal of this interventional study is to compare standard mechanical ventilation to a lung-stress oriented ventilation strategy in patients with Acute Respiratory Distress Syndrome (ARDS). Participants will be ventilated according to one of two different strategies. The main question the study hopes to answer is whether the personalized ventilation strategy helps improve survival.
Study identification
- NCT ID
- NCT06066502
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,100 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 23, 2024
- Primary completion
- Jun 30, 2030
- Completion
- Dec 30, 2030
- Last update posted
- Jun 28, 2026
2024 – 2030
United States locations
- U.S. sites
- 33
- U.S. states
- 19
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arizona | Tucson | Arizona | 85724 | Recruiting |
| University of Arkansas for Medical Sciences | Little Rock | Arkansas | 72205 | Recruiting |
| University of California, San Diego | La Jolla | California | 92093 | Recruiting |
| University of California, Los Angeles Medical Center | Los Angeles | California | 90024 | Recruiting |
| Cedar-Sinai Medical Center | Los Angeles | California | 90048 | Recruiting |
| Stanford University | Palo Alto | California | 94305 | Recruiting |
| University of California, San Francisco | San Franciso | California | 94143 | Recruiting |
| University of Miami | Miami | Florida | 33136 | Recruiting |
| Emory University / Grady Health System | Atlanta | Georgia | 30322 | Not yet recruiting |
| University of Chicago | Chicago | Illinois | 60637 | Recruiting |
| Tufts Medical Center | Boston | Massachusetts | 02111 | Recruiting |
| Massachusetts General Hospital | Boston | Massachusetts | 02114 | Recruiting |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | Recruiting |
| Beth Israel Deaconess Medical Center | Boston | Massachusetts | 02215 | Recruiting |
| Lowell General Hospital | Lowell | Massachusetts | 01854 | Not yet recruiting |
| University of Michigan | Ann Arbor | Michigan | 48109 | Recruiting |
| Mayo Clinic | Rochester | Minnesota | 55905 | Recruiting |
| NYU Lagone Health | New York | New York | 02114 | Recruiting |
| New York City Health + Hospitals/ Bellevue | New York | New York | 10016 | Recruiting |
| Albert Einstein College of Medicine/Montefiore Medical Center | The Bronx | New York | 10461 | Recruiting |
| Duke University Medical Center | Durham | North Carolina | 27710 | Recruiting |
| Atrium Health Wake Forest Baptist | Winston-Salem | North Carolina | 27157 | Recruiting |
| University of Cincinnati | Cincinnati | Ohio | 45267 | Recruiting |
| Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | Recruiting |
| Ohio State University Wexner Medical Center | Columbus | Ohio | 43210 | Recruiting |
| University of Oklahoma Health Sciences | Oklahoma City | Oklahoma | 73104 | Not yet recruiting |
| Oregon Health & Science University | Portland | Oregon | 97239 | Recruiting |
| Thomas Jefferson University | Philadelphia | Pennsylvania | 19107 | Recruiting |
| Baylor College of Medicine / St. Luke's Medical Center | Houston | Texas | 77030 | Recruiting |
| Intermountain Health | Murray | Utah | 84107 | Recruiting |
| University of Utah | Salt Lake City | Utah | 84132 | Recruiting |
| University of Virginia | Charlottesville | Virginia | 22908 | Recruiting |
| University of Washingont/Harborview Medical Center | Seattle | Washington | 98104 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06066502, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jun 28, 2026 · Synced Sep 5, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06066502 live on ClinicalTrials.gov.