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Completed No phase listed Observational

The CARDIO-TTRansform Scintigraphy Sub-study

ClinicalTrials.gov ID: NCT06073587

Public ClinicalTrials.gov record NCT06073587. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 21, 2026, 5:09 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

CARDIO-TTRansform ION-682884-CS2-Scintigraphy Sub-study

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to examine the changes in amyloid myocardial burden in a subset of the population participating in the ION682884-CS2 (NCT04136171) study, up to 150 participants, after treatment with eplontersen or placebo based on scintigraphy scans performed at Week 140 using the Perugini grade score method.

Study identification

NCT ID
NCT06073587
Recruitment status
Completed
Study type
Observational
Phase
Not listed
Lead sponsor
Ionis Pharmaceuticals, Inc.
Industry
Enrollment
163 participants

Conditions and interventions

Interventions

Diagnostic Test

Eligibility (public fields only)

Age range
18 Years to 90 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Apr 4, 2023 (Actual)
Primary completion
Mar 25, 2026 (Actual)
Completion
Mar 25, 2026 (Actual)
Last update posted
Sep 11, 2026

2023 – 2026

United States locations

U.S. sites
4
U.S. states
4
U.S. cities
4
Facility City State ZIP Site status
Columbia University Irving Medical Center New York New York 10032 —
Duke University Medical Center Durham North Carolina 27710 —
Cleveland Clinic Main Campus Cleveland Ohio 44195 —
Oregon Health and Science University Portland Oregon 97239 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06073587, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 11, 2026 · Synced Oct 21, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT06073587 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →