Study to Evaluate the Safety and Efficacy of PIPE-307 in Subjects With Relapsing-Remitting Multiple Sclerosis
Public ClinicalTrials.gov record NCT06083753. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Dose-Ranging Multicenter Study to Evaluate the Safety and Efficacy of Oral PIPE-307 as an Adjunctive Treatment in Subjects With Relapsing-Remitting Multiple Sclerosis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
This is a randomized, double-blind study of PIPE-307 or placebo in subjects with relapsing-remitting multiple sclerosis. Subjects will be randomized into 1 of 3 separate cohorts (1:1:1 randomization ratio, PIPE-307 Dose A:PIPE-307 Dose B: Placebo) for a total duration of approximately 30 weeks.
Study identification
- NCT ID
- NCT06083753
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 182 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 50 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 6, 2023 (Actual)
- Primary completion
- Jul 14, 2025 (Actual)
- Completion
- Aug 4, 2025 (Actual)
- Last update posted
- Sep 25, 2026
2023 – 2025
United States locations
- U.S. sites
- 21
- U.S. states
- 14
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Xenosciences | Phoenix | Arizona | 85004 | — |
| Arizona Neuroscience Research, LLC | Phoenix | Arizona | 85032 | — |
| Alta Bates Summit Medical Center | Berkeley | California | 94705 | — |
| Colorado Springs Neurological Associates | Colorado Springs | Colorado | 80907 | — |
| MS and Neuromuscular Center of Excellence | Clearwater | Florida | 33761 | — |
| Aqualane Clinical Research | Naples | Florida | 34105 | — |
| Shepherd Center | Atlanta | Georgia | 30309 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Neurology Center of New England P.C. | Foxborough | Massachusetts | 02035 | — |
| Washington University School of Medicine | St Louis | Missouri | 63110 | — |
| University of New Mexico/Health Science Center/MIND Imaging Center/MS Specialty Clinic | Albuquerque | New Mexico | 87106 | — |
| Dent Neurologic Institute | Amherst | New York | 14226 | — |
| Neurological Associates of Long Island, P.C. | Lake Success | New York | 11042 | — |
| Oklahoma Research Foundation - MS Center of Excellence | Oklahoma City | Oklahoma | 73104 | — |
| Sibyl Wray Neurology PC | Knoxville | Tennessee | 37922 | — |
| University of Texas Health Science Center at Houston | Houston | Texas | 77030 | — |
| Clinical Trial Network | Houston | Texas | 77074 | — |
| Bhupesh Dihenia, MD, PA | Lubbock | Texas | 79410 | — |
| Virginia Mason Medical Center | Seattle | Washington | 98101 | — |
| UW Medicine MS Center | Seattle | Washington | 98133 | — |
| Multicare Neuroscience Center of Washington | Tacoma | Washington | 98405 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06083753, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 25, 2026 · Synced Oct 14, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06083753 live on ClinicalTrials.gov.