A Study About How Well TAK-279 Works and Its Safety in Participants With Moderate-to-severe Plaque Psoriasis During 52 Weeks of Treatment
Public ClinicalTrials.gov record NCT06088043. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Multicenter, Double-Blind, Placebo- and Active Comparator-Controlled Study to Evaluate the Efficacy, Safety, and Tolerability of TAK-279 in Subjects With Moderate-to-Severe Plaque Psoriasis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main aim of this study is to show how well TAK-279 reduces the skin plaques compared to placebo, in participants with moderate-to-severe plaque psoriasis. Participants will be assigned to one of the 3 study treatments (TAK-279, apremilast (an approved treatment), or a placebo). Participants will be in the study for up to 61 weeks.
Study identification
- NCT ID
- NCT06088043
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 693 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 6, 2023 (Actual)
- Primary completion
- Jan 22, 2025 (Actual)
- Completion
- Oct 22, 2025 (Actual)
- Last update posted
- Oct 24, 2025
2023 – 2025
United States locations
- U.S. sites
- 27
- U.S. states
- 17
- U.S. cities
- 27
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Saguaro Dermatology Associates, LLC - Probity - PPDS | Phoenix | Arizona | 85008-3884 | — |
| First OC Dermatology - Fountain Valley | Fountain Valley | California | 92708-3701 | — |
| Center for Dermatology Clinical Research | Fremont | California | 94538-1614 | — |
| UCLA University of California Los Angeles | Los Angeles | California | 90024 | — |
| UC Davis Dermatology Clinic | Sacramento | California | 95816-3370 | — |
| Driven Research LLC | Coral Gables | Florida | 33134-3901 | — |
| FXM Clinical Research Ft. Lauderdale, LLC | Fort Lauderdale | Florida | 33308-5211 | — |
| Direct Helpers Research Center | Hialeah | Florida | 33012-3618 | — |
| FXM Clinical Research Miami, LLC | Miami | Florida | 33175-3582 | — |
| Renstar Medical Research -21 NE 1st Ave | Ocala | Florida | 34470-6657 | — |
| Marietta Dermatology & The Skin Cancer Center - Marietta | Marietta | Georgia | 30060-7902 | — |
| Leavitt Clinical Research - 1542 Elk Creek Dr | Idaho Falls | Idaho | 83404-8322 | — |
| Arlington Dermatology | Rolling Meadows | Illinois | 60008-3811 | — |
| Dawes Fretzin Clinical Research Group-7910 N Shadeland Ave | Indianapolis | Indiana | 46256-4697 | — |
| Kindred Hair & Skin Center - CAR | Columbia | Maryland | 21046-1246 | — |
| Revival Research Corporation - Michigan - ClinEdge - PPDS | Troy | Michigan | 48084-3536 | — |
| Grekin Skin Institute | Warren | Michigan | 48088-3671 | — |
| Henderson Clinical Trials | Henderson | Nevada | 89052-5016 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03766-1937 | — |
| ALLCUTIS Research, LLC. | Portsmouth | New Hampshire | 03801-6822 | — |
| Northwell Health Physician Partners Dermatology at Lake Success - BRANY - PPDS | New York | New York | 10003-3314 | — |
| Accellacare of Cary | Cary | North Carolina | 27518-7414 | — |
| Bexley Dermatology Research - Probity - PPDS | Bexley | Ohio | 43209 | — |
| Clinical Research Center of the Carolinas, LLC | Charleston | South Carolina | 29407-5347 | — |
| International Clinical Research-Tennessee LLC | Murfreesboro | Tennessee | 37130-2450 | — |
| Bellaire Dermatology Associates | Bellaire | Texas | 77401-3505 | — |
| Progressive Clinical Research PA - San Antonio | San Antonio | Texas | 78213-2250 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 105 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06088043, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 24, 2025 · Synced Oct 19, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06088043 live on ClinicalTrials.gov.