A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)
Public ClinicalTrials.gov record NCT06095128. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
An Open-Label, Phase 4, Single-Arm, Multicenter Study to Evaluate the Induction of Response and Remission of Vedolizumab Dual Targeted Therapy With Tofacitinib in Adult Patients With Moderately to Severely Active Ulcerative Colitis
Study identification
- NCT ID
- NCT06095128
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Phase 4
- Lead sponsor
- Takeda
- Industry
- Enrollment
- 65 participants
Conditions and interventions
Conditions
Interventions
- Tofacitinib Drug
- Vedolizumab Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 65 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 11, 2024
- Primary completion
- Jul 8, 2027
- Completion
- Jul 8, 2027
- Last update posted
- Mar 17, 2026
2024 – 2027
United States locations
- U.S. sites
- 40
- U.S. states
- 22
- U.S. cities
- 39
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Digestive Health Specialsits | Dothan | Alabama | 36301 | Recruiting |
| GI Alliance Sun City | Sun City | Arizona | 85351 | Recruiting |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | Recruiting |
| Hoag Hospital Newport Beach | Newport Beach | California | 92663 | Recruiting |
| Endoscopic Research Inc | Orlando | Florida | 32803 | Recruiting |
| Alliance Clinical Research of Tampa, LLC | Tampa | Florida | 33615 | Recruiting |
| Gastroenterology Consultants, P.C. | Roswell | Georgia | 30076 | Recruiting |
| University of Chicago Medicine | Chicago | Illinois | 60637 | Recruiting |
| GI Alliance - Illinois Gastroenterology Group - Glenview | Glenview | Illinois | 60026 | Recruiting |
| GI Alliance - Illinois Gastroenterology Group LLC - Gurnee | Gurnee | Illinois | 60031 | Recruiting |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | Recruiting |
| University of Louisville | Louisville | Kentucky | 40202 | Recruiting |
| GI Alliance | Metairie | Louisiana | 70006 | Recruiting |
| Tulane University | New Orleans | Louisiana | 70112 | Recruiting |
| Capital Digestive Care - MGG Group - Chevy Chase Clinical Research | Chevy Chase | Maryland | 20815 | Recruiting |
| Huron Gastroenterology Associates, P.C. | Ypsilanti | Michigan | 48197 | Recruiting |
| MNGI Digestive Health, PA | Plymouth | Minnesota | 55446 | Recruiting |
| Mid-America Gastro-Intestinal Consultants | Kansas City | Missouri | 64111 | Recruiting |
| BVL Clinical Research | Liberty | Missouri | 64068 | Recruiting |
| Washington University School of Medicine | St Louis | Missouri | 63110 | Recruiting |
| NYU Langone Health | New York | New York | 10016 | Recruiting |
| Weill Cornell Medical College- New York Presbyterian Hospital | New York | New York | 10065 | Recruiting |
| Digestive Health Partners | Asheville | North Carolina | 28801 | Recruiting |
| University of North Carolina | Chapel Hill | North Carolina | 27599 | Recruiting |
| University of Cincinnati | Cincinnati | Ohio | 45627 | Recruiting |
| Ohio Gastroenterology group, Inc. | Columbus | Ohio | 43202 | Recruiting |
| Gastro Intestinal Research Institute of Northern Ohio, LLC. | Westlake | Ohio | 44145 | Recruiting |
| Allegheny Health Network | Wexford | Pennsylvania | 15090 | Recruiting |
| University Gastroenterology | Providence | Rhode Island | 02905 | Recruiting |
| Rapid City Medical Center, LLP | Rapid City | South Dakota | 57701 | Recruiting |
| GI Alliance - Digestive Health Associates of Texas | Dallas | Texas | 75044 | Recruiting |
| The University of Texas Health Science Center at Houston | Houston | Texas | 77030 | Recruiting |
| GI Alliance - Mansfield | Mansfield | Texas | 76063 | Recruiting |
| Gastroenterology Research of San Antonio, LLC | San Antonio | Texas | 78229 | Recruiting |
| Texas Digestive Disease Consultants (TDDC), Southlake | Southlake | Texas | 76092 | Recruiting |
| Tyler Research Institute, LLC | Tyler | Texas | 75701 | Recruiting |
| GI Alliance - Webster | Webster | Texas | 77598 | Recruiting |
| University of Utah Health | Salt Lake City | Utah | 84108 | Recruiting |
| Washington Gastroenterology- GIA | Bellevue | Washington | 98004 | Withdrawn |
| Washington Gastroenterology- GIA | Tacoma | Washington | 98405 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 9 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06095128, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Mar 17, 2026 · Synced May 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06095128 live on ClinicalTrials.gov.