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Active, not recruiting Phase 2 Interventional

A Study Evaluating Atezolizumab, With or Without Bevacizumab, in Participants With Unresectable Hepatocellular Carcinoma and Child-pugh B7 and B8 Cirrhosis

ClinicalTrials.gov ID: NCT06096779

Public ClinicalTrials.gov record NCT06096779. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Nov 3, 2026, 2:07 PM EST

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase II, Open-label, Multi-cohort, Multicenter Study in Patients With Unresectable Hepatocellular Carcinoma and Child-pugh B7 and B8 Cirrhosis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to assess the safety of atezolizumab and bevacizumab, or atezolizumab alone, as first-line treatment in participants with unresectable, locally advanced or metastatic hepatocellular carcinoma (HCC) with Child-pugh B7 or B8 cirrhosis.

Study identification

NCT ID
NCT06096779
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Genentech, Inc.
Industry
Enrollment
30 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Jul 15, 2024 (Actual)
Primary completion
Jul 30, 2027 (Estimated)
Completion
Dec 30, 2027 (Estimated)
Last update posted
Oct 8, 2026

2024 – 2027

United States locations

U.S. sites
53
U.S. states
23
U.S. cities
41
Facility City State ZIP Site status
University of Arizona Cancer Center Tucson Arizona 85724 —
UC San Diego Moores Cancer Center La Jolla California 92093 —
University of Southern California-Keck School of Medicine -1975 Zonal Ave Los Angeles California 90089-5601 —
University of Southern California Newport Beach California 92663 —
University of California Irvine Medical Center Orange California 92868 —
California Liver Research Institute Pasadena California 91105-2561 —
University of California Davis Medical Center Sacramento California 95817 —
Stanford Health Care Stanford California 94305 —
Harbor UCLA Medical Center Torrance California 90502-2006 —
Cedars Sinai Comprehensive Transplant Center West Hollywood California 90048-2422 —
Hartford Healthcare Cancer Institute at Hartford Hospital Hartford Connecticut 06106 —
George Washington University- Medical Faculty Associates Washington D.C. District of Columbia 20037 —
Washington DC VA Medical Center Washington D.C. District of Columbia 20422-0001 —
Orlando Health Inc. Orlando Florida 32806 —
Northwestern University Chicago Illinois 60611-2908 —
University of Illinois Health Outpatient Care Center Chicago Illinois 60612-4795 —
The Duchossois Center for Advanced Medicine Chicago Illinois 60637-1426 —
University of Kentucky - Markey Cancer Center Lexington Kentucky 40536-7001 —
LSU Health Baton Rouge Baton Rouge Louisiana 70805 —
Our Lady of the Lake Cancer Institute Baton Rouge Louisiana 70808-4300 —
Tufts Medical Center Boston Massachusetts 02111 —
Beth Israel Deaconess Medical Center Boston Massachusetts 02215 —
Barbara Ann Karmanos Cancer Institute Detroit Michigan 48201 —
Henry Ford Health System Detroit Michigan 48202 —
Saint Luke?s Hospital of Kansas City Kansas City Missouri 64111 —
Rutgers Cancer Institute of New Jersey New Brunswick New Jersey 08901 —
Rutgers Cancer Institute of New Jersey at University Hospital Newark New Jersey 07103 —
NYU Langone Hospital - Long Island Mineola New York 11501-4064 —
Icahn School of Medicine at Mount Sinai New York New York 10029 —
Montefiore Medical Center The Bronx New York 10467 —
James J Peters Veterans Administration Medical Center - NAVREF The Bronx New York 10468-3904 —
Levine Cancer Institute Charlotte North Carolina 28204 —
Dayton VA Medical Center - NAVREF - PPDS Dayton Ohio 45428-9000 —
The University of Oklahoma Health Sciences Center Oklahoma City Oklahoma 73104-5020 —
Kaiser Permanente Westside Medical Center Hillsboro Oregon 97124-5806 —
OHSU Knight Cancer Institute Hematology Oncology Portland Oregon 97239-3011 —
Jefferson Health Honickman Center Philadelphia Pennsylvania 19107 —
Veterans Affairs Pittsburgh Healthcare System - NAVREF - PPDS Pittsburgh Pennsylvania 15240 —
The West Clinic (East Campus) Germantown Tennessee 38138-1762 —
Nashville General Hospital at Meharry Nashville Tennessee 37208-2918 —
Liver Institute at Methodist Dallas Dallas Texas 75203-1260 —
Moody Outpatient Center ? Parkland Health Dallas Texas 75235 —
Texas Oncology (Worth) - USOR Dallas Texas 75246-2008 —
University of Texas Southwestern Medical Center Dallas Texas 75390-0001 —
Texas Oncology - Denison Cancer Center Denison Texas 75020-0084 —
Kelsey Research Foundation Houston Texas 77025-1669 —
Michael E Debakey VA Medical Center - NAVREF - PPDS Houston Texas 77030-4211 —
Intermountain Healthcare Murray Utah 84107-5741 —
Intermountain Cancer Center St. George Utah 84790 —
Inova Schar Cancer Institute Falls Church Virginia 22042 —
Bon Secours St. Mary's Hospital Richmond Virginia 23226-1925 —
VCU Medical Center North Hospital Richmond Virginia 23298-5028 —
Virginia Mason Medical Center Seattle Washington 98101 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 1 non-U.S. site.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06096779, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 8, 2026 · Synced Nov 3, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT06096779 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →