Randomized, Double-blind Study of Efficacy and Safety of Bexotegrast (PLN-74809) for Idiopathic Pulmonary Fibrosis
Public ClinicalTrials.gov record NCT06097260. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Dose-ranging, Placebo-controlled Study to Evaluate the Efficacy and Safety of Bexotegrast (PLN-74809) for the Treatment of Idiopathic Pulmonary Fibrosis (BEACON-IPF)
Study identification
- NCT ID
- NCT06097260
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Pliant Therapeutics, Inc.
- Industry
- Enrollment
- 320 participants
Conditions and interventions
Conditions
Interventions
- PLN-74809 Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 40 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 15, 2023
- Primary completion
- Apr 3, 2025
- Completion
- Apr 3, 2025
- Last update posted
- Jul 31, 2025
2023 – 2025
United States locations
- U.S. sites
- 79
- U.S. states
- 32
- U.S. cities
- 72
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Alabama at Birmingham | Birmingham | Alabama | 35294 | — |
| Arizona Pulmonary Specialists | Phoenix | Arizona | 85012 | — |
| Dignity Health-St. Josephs Hospital and Medical Center | Phoenix | Arizona | 85013 | — |
| Banner University Medical Center | Tucson | Arizona | 85724 | — |
| Cedars Sinai Medical Center | Los Angeles | California | 90048 | — |
| Newport Native MD, Inc | Newport Beach | California | 92663 | — |
| Palmtree Clinical Research | Palm Springs | California | 92262 | — |
| VA Palo Alto Health Care System | Palo Alto | California | 94304 | — |
| Paradigm Clinical Research Institute Inc - ClinEdge | Redding | California | 96001 | — |
| University of California Davis Comprehensive Cancer Center | Sacramento | California | 95807 | — |
| UCSF Medical Center - Pulmonary Practice | San Francisco | California | 94143 | — |
| Jeffrey S. Sager, MD Medical Corporation | Santa Barbara | California | 93105 | — |
| Stanford Health Care | Stanford | California | 94305 | — |
| University of Colorado | Aurora | Colorado | 80048 | — |
| National Jewish Health Main Campus | Denver | Colorado | 80206 | — |
| Critical Care, Pulmonary and Sleep Associates | Lakewood | Colorado | 80228 | — |
| Nuvance Health Medical Practices, Pulmonary & Sleep Specialists | Danbury | Connecticut | 06810 | — |
| Yale New Haven Hospital - York Street Campus | New Haven | Connecticut | 06510 | — |
| MedStar Georgetown University Hospital | Washington D.C. | District of Columbia | 20007 | — |
| Malcom Randall VA Medical Center | Gainesville | Florida | 32608 | — |
| Mayo Clinic Jacksonville | Jacksonville | Florida | 32224 | — |
| Clinical Research Specialists, LLC | Kissimmee | Florida | 34746 | — |
| Clinical Site Partners - Leesburg | Leesburg | Florida | 34738 | — |
| Central Florida Pulmonary Group PA | Orlando | Florida | 32803 | — |
| GCP Clinical Research | Tampa | Florida | 33609 | — |
| Emory Clinic | Atlanta | Georgia | 30322 | — |
| Augusta University | Augusta | Georgia | 30912 | — |
| Northwestern Memorial Hospital | Chicago | Illinois | 60611 | — |
| Loyola University Medical Center | Maywood | Illinois | 60153 | — |
| IU Health Advanced Heart and Lung Care | Indianapolis | Indiana | 46202 | — |
| University of Kansas Medical Center | Kansas City | Kansas | 66160 | — |
| Lexington VA Medical Center | Lexington | Kentucky | 40508 | — |
| Norton Pulmonary Specialists | Louisville | Kentucky | 40202 | — |
| Tulane Medical Center | New Orleans | Louisiana | 70112 | — |
| University of Maryland Medical Center | Baltimore | Maryland | 21201 | — |
| The Johns Hopkins Hospital JHH | Baltimore | Maryland | 21224 | — |
| Massachusetts General Hospital - Pulmonary Associates | Boston | Massachusetts | 02114 | — |
| Brigham and Womans Hospital | Boston | Massachusetts | 02115 | — |
| Beth Israel Deaconess Medical Cente | Boston | Massachusetts | 02215 | — |
| Infinity Medical Research | North Dartmouth | Massachusetts | 02747 | — |
| University of Michigan Health System | Ann Arbor | Michigan | 48109 | — |
| Henry Ford Health System | Detroit | Michigan | 48202 | — |
| University of Minnesota Medical Center, Fairview | Minneapolis | Minnesota | 55455 | — |
| Mayo Clinic | Rochester | Minnesota | 55905 | — |
| The Lung Research Center | Chesterfield | Missouri | 63017 | — |
| Dartmouth Hitchcock Medical Center | Lebanon | New Hampshire | 03756 | — |
| Icahn School of Medicine at Mount Sinai | New York | New York | 10029 | — |
| New York Presbyterian Hospital-Columbia University Medical Center | New York | New York | 10032 | — |
| Weill Cornell Medicine | New York | New York | 10032 | — |
| Montefiore Medical Center Moses Division Hospital | The Bronx | New York | 10467 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| PulmonIx, LLC | Greensboro | North Carolina | 27403 | — |
| Southeastern Research Center | Winston-Salem | North Carolina | 27103 | — |
| University of Cincinnati | Cincinnati | Ohio | 45267 | — |
| The Cleveland Clinic Foundation | Cleveland | Ohio | 44195 | — |
| OU Health Physicians | Oklahoma City | Oklahoma | 73104 | — |
| Bend Memorial Clinic/Summit Medical Group - Eastside | Bend | Oregon | 97701 | — |
| Legacy Good Samaritan Hospital | Portland | Oregon | 97232 | — |
| Clinical Research Associates Of Central PA , LLC | DuBois | Pennsylvania | 15801 | — |
| Penn State Health Milton S. Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Perelman Center for Advanced Medicine | Philadelphia | Pennsylvania | 19104 | — |
| University of Pittsburgh Medical Center | Pittsburgh | Pennsylvania | 15213 | — |
| Medical University of South Carolina | Charleston | South Carolina | 29425 | — |
| Velocity Clinical Research | Greenville | South Carolina | 29615 | — |
| Lowcountry Lung and Critical Care PA | North Charleston | South Carolina | 29406 | — |
| Clinical Trials Center of Middle Tennessee | Franklin | Tennessee | 37067 | — |
| Statcare Pulmonary Consultants - Knoxville | Knoxville | Tennessee | 37909 | — |
| University of Tennessee Medical Center | Knoxville | Tennessee | 37920 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37204 | — |
| Baylor Scott and White Health - Advanced Lung Disease Specialists | Dallas | Texas | 75246 | — |
| El Paso Pulmonary Association | El Paso | Texas | 79902 | — |
| Baylor College of Medicine | Houston | Texas | 77030 | — |
| Research Centers of America | McKinney | Texas | 75071 | — |
| Renovatio Clinical Research | The Woodlands | Texas | 77380 | — |
| Topline Clinical Research | Waxahachie | Texas | 75165 | — |
| University of Utah | Salt Lake City | Utah | 84108 | — |
| University of Vermont Medical Center | Burlington | Vermont | 05401 | — |
| INOVA Fairfax Medical Campus | Falls Church | Virginia | 22042 | — |
| Western Washington Medical Group | Everett | Washington | 98208 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 189 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06097260, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 31, 2025 · Synced May 5, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06097260 live on ClinicalTrials.gov.