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Terminated Phase 2 Interventional

Randomized, Double-blind Study of Efficacy and Safety of Bexotegrast (PLN-74809) for Idiopathic Pulmonary Fibrosis

ClinicalTrials.gov ID: NCT06097260

Public ClinicalTrials.gov record NCT06097260. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced May 5, 2026, 10:54 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Dose-ranging, Placebo-controlled Study to Evaluate the Efficacy and Safety of Bexotegrast (PLN-74809) for the Treatment of Idiopathic Pulmonary Fibrosis (BEACON-IPF)

Study identification

NCT ID
NCT06097260
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Pliant Therapeutics, Inc.
Industry
Enrollment
320 participants

Conditions and interventions

Interventions

  • PLN-74809 Drug
  • Placebo Drug

Drug

Eligibility (public fields only)

Age range
40 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 15, 2023
Primary completion
Apr 3, 2025
Completion
Apr 3, 2025
Last update posted
Jul 31, 2025

2023 – 2025

United States locations

U.S. sites
79
U.S. states
32
U.S. cities
72
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35294
Arizona Pulmonary Specialists Phoenix Arizona 85012
Dignity Health-St. Josephs Hospital and Medical Center Phoenix Arizona 85013
Banner University Medical Center Tucson Arizona 85724
Cedars Sinai Medical Center Los Angeles California 90048
Newport Native MD, Inc Newport Beach California 92663
Palmtree Clinical Research Palm Springs California 92262
VA Palo Alto Health Care System Palo Alto California 94304
Paradigm Clinical Research Institute Inc - ClinEdge Redding California 96001
University of California Davis Comprehensive Cancer Center Sacramento California 95807
UCSF Medical Center - Pulmonary Practice San Francisco California 94143
Jeffrey S. Sager, MD Medical Corporation Santa Barbara California 93105
Stanford Health Care Stanford California 94305
University of Colorado Aurora Colorado 80048
National Jewish Health Main Campus Denver Colorado 80206
Critical Care, Pulmonary and Sleep Associates Lakewood Colorado 80228
Nuvance Health Medical Practices, Pulmonary & Sleep Specialists Danbury Connecticut 06810
Yale New Haven Hospital - York Street Campus New Haven Connecticut 06510
MedStar Georgetown University Hospital Washington D.C. District of Columbia 20007
Malcom Randall VA Medical Center Gainesville Florida 32608
Mayo Clinic Jacksonville Jacksonville Florida 32224
Clinical Research Specialists, LLC Kissimmee Florida 34746
Clinical Site Partners - Leesburg Leesburg Florida 34738
Central Florida Pulmonary Group PA Orlando Florida 32803
GCP Clinical Research Tampa Florida 33609
Emory Clinic Atlanta Georgia 30322
Augusta University Augusta Georgia 30912
Northwestern Memorial Hospital Chicago Illinois 60611
Loyola University Medical Center Maywood Illinois 60153
IU Health Advanced Heart and Lung Care Indianapolis Indiana 46202
University of Kansas Medical Center Kansas City Kansas 66160
Lexington VA Medical Center Lexington Kentucky 40508
Norton Pulmonary Specialists Louisville Kentucky 40202
Tulane Medical Center New Orleans Louisiana 70112
University of Maryland Medical Center Baltimore Maryland 21201
The Johns Hopkins Hospital JHH Baltimore Maryland 21224
Massachusetts General Hospital - Pulmonary Associates Boston Massachusetts 02114
Brigham and Womans Hospital Boston Massachusetts 02115
Beth Israel Deaconess Medical Cente Boston Massachusetts 02215
Infinity Medical Research North Dartmouth Massachusetts 02747
University of Michigan Health System Ann Arbor Michigan 48109
Henry Ford Health System Detroit Michigan 48202
University of Minnesota Medical Center, Fairview Minneapolis Minnesota 55455
Mayo Clinic Rochester Minnesota 55905
The Lung Research Center Chesterfield Missouri 63017
Dartmouth Hitchcock Medical Center Lebanon New Hampshire 03756
Icahn School of Medicine at Mount Sinai New York New York 10029
New York Presbyterian Hospital-Columbia University Medical Center New York New York 10032
Weill Cornell Medicine New York New York 10032
Montefiore Medical Center Moses Division Hospital The Bronx New York 10467
Duke University Medical Center Durham North Carolina 27710
PulmonIx, LLC Greensboro North Carolina 27403
Southeastern Research Center Winston-Salem North Carolina 27103
University of Cincinnati Cincinnati Ohio 45267
The Cleveland Clinic Foundation Cleveland Ohio 44195
OU Health Physicians Oklahoma City Oklahoma 73104
Bend Memorial Clinic/Summit Medical Group - Eastside Bend Oregon 97701
Legacy Good Samaritan Hospital Portland Oregon 97232
Clinical Research Associates Of Central PA , LLC DuBois Pennsylvania 15801
Penn State Health Milton S. Hershey Medical Center Hershey Pennsylvania 17033
Perelman Center for Advanced Medicine Philadelphia Pennsylvania 19104
University of Pittsburgh Medical Center Pittsburgh Pennsylvania 15213
Medical University of South Carolina Charleston South Carolina 29425
Velocity Clinical Research Greenville South Carolina 29615
Lowcountry Lung and Critical Care PA North Charleston South Carolina 29406
Clinical Trials Center of Middle Tennessee Franklin Tennessee 37067
Statcare Pulmonary Consultants - Knoxville Knoxville Tennessee 37909
University of Tennessee Medical Center Knoxville Tennessee 37920
Vanderbilt University Medical Center Nashville Tennessee 37204
Baylor Scott and White Health - Advanced Lung Disease Specialists Dallas Texas 75246
El Paso Pulmonary Association El Paso Texas 79902
Baylor College of Medicine Houston Texas 77030
Research Centers of America McKinney Texas 75071
Renovatio Clinical Research The Woodlands Texas 77380
Topline Clinical Research Waxahachie Texas 75165
University of Utah Salt Lake City Utah 84108
University of Vermont Medical Center Burlington Vermont 05401
INOVA Fairfax Medical Campus Falls Church Virginia 22042
Western Washington Medical Group Everett Washington 98208

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 189 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06097260, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Jul 31, 2025 · Synced May 5, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06097260 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →