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Terminated Phase 2 Interventional Results available

Randomized, Double-blind Study of Efficacy and Safety of Bexotegrast (PLN-74809) for Idiopathic Pulmonary Fibrosis

ClinicalTrials.gov ID: NCT06097260

Public ClinicalTrials.gov record NCT06097260. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 14, 2026, 1:47 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Randomized, Double-blind, Dose-ranging, Placebo-controlled Study to Evaluate the Efficacy and Safety of Bexotegrast (PLN-74809) for the Treatment of Idiopathic Pulmonary Fibrosis (BEACON-IPF)

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

A randomized, double-blind, dose-ranging, placebo-controlled study to evaluate the efficacy and safety of bexotegrast (PLN-74809) for the treatment of idiopathic pulmonary fibrosis (BEACON-IPF).

Study identification

NCT ID
NCT06097260
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Pliant Therapeutics, Inc.
Industry
Enrollment
320 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
40 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 16, 2023 (Actual)
Primary completion
Apr 4, 2025 (Actual)
Completion
Apr 4, 2025 (Actual)
Last update posted
Aug 5, 2026

2023 – 2025

United States locations

U.S. sites
79
U.S. states
32
U.S. cities
72
Facility City State ZIP Site status
University of Alabama at Birmingham Birmingham Alabama 35294 —
Arizona Pulmonary Specialists Phoenix Arizona 85012 —
Dignity Health-St. Josephs Hospital and Medical Center Phoenix Arizona 85013 —
Banner University Medical Center Tucson Arizona 85724 —
Cedars Sinai Medical Center Los Angeles California 90048 —
Newport Native MD, Inc New Port Beach California 92663 —
Palmtree Clinical Research Palm Springs California 92262 —
VA Palo Alto Health Care System Palo Alto California 94304 —
Paradigm Clinical Research Institute Inc - ClinEdge Redding California 96001 —
University of California Davis Comprehensive Cancer Center Sacramento California 95807 —
UCSF Medical Center - Pulmonary Practice San Francisco California 94143 —
Jeffrey S. Sager, MD Medical Corporation Santa Barbara California 93105 —
Stanford Health Care Stanford California 94305 —
University of Colorado Aurora Colorado 80048 —
National Jewish Health Main Campus Denver Colorado 80206 —
Critical Care, Pulmonary and Sleep Associates Lakewood Colorado 80228 —
Nuvance Health Medical Practices, Pulmonary & Sleep Specialists Danbury Connecticut 06810 —
Yale New Haven Hospital - York Street Campus New Haven Connecticut 06510 —
MedStar Georgetown University Hospital Washington D.C. District of Columbia 20007 —
Malcom Randall VA Medical Center Gainesville Florida 32608 —
Mayo Clinic Jacksonville Jacksonville Florida 32224 —
Clinical Research Specialists, LLC Kissimmee Florida 34746 —
Clinical Site Partners - Leesburg Leesburg Florida 34738 —
Central Florida Pulmonary Group PA Orlando Florida 32803 —
GCP Clinical Research Tampa Florida 33609 —
Emory Clinic Atlanta Georgia 30322 —
Augusta University Augusta Georgia 30912 —
Northwestern Memorial Hospital Chicago Illinois 60611 —
Loyola University Medical Center Maywood Illinois 60153 —
IU Health Advanced Heart and Lung Care Indianapolis Indiana 46202 —
University of Kansas Medical Center Kansas City Kansas 66160 —
Lexington VA Medical Center Lexington Kentucky 40508 —
Norton Pulmonary Specialists Louisville Kentucky 40202 —
Tulane Medical Center New Orleans Louisiana 70112 —
University of Maryland Medical Center Baltimore Maryland 21201 —
The Johns Hopkins Hospital JHH Baltimore Maryland 21224 —
Massachusetts General Hospital - Pulmonary Associates Boston Massachusetts 02114 —
Brigham and Womans Hospital Boston Massachusetts 02115 —
Beth Israel Deaconess Medical Cente Boston Massachusetts 02215 —
Infinity Medical Research North Dartmouth Massachusetts 02747 —
University of Michigan Health System Ann Arbor Michigan 48109 —
Henry Ford Health System Detroit Michigan 48202 —
University of Minnesota Medical Center, Fairview Minneapolis Minnesota 55455 —
Mayo Clinic Rochester Minnesota 55905 —
The Lung Research Center Chesterfield Missouri 63017 —
Dartmouth Hitchcock Medical Center Lebanon New Hampshire 03756 —
Icahn School of Medicine at Mount Sinai New York New York 10029 —
New York Presbyterian Hospital-Columbia University Medical Center New York New York 10032 —
Weill Cornell Medicine New York New York 10032 —
Montefiore Medical Center Moses Division Hospital The Bronx New York 10467 —
Duke University Medical Center Durham North Carolina 27710 —
PulmonIx, LLC Greensboro North Carolina 27403 —
Southeastern Research Center Winston-Salem North Carolina 27103 —
University of Cincinnati Cincinnati Ohio 45267 —
The Cleveland Clinic Foundation Cleveland Ohio 44195 —
OU Health Physicians Oklahoma City Oklahoma 73104 —
Bend Memorial Clinic/Summit Medical Group - Eastside Bend Oregon 97701 —
Legacy Good Samaritan Hospital Portland Oregon 97232 —
Clinical Research Associates Of Central PA , LLC DuBois Pennsylvania 15801 —
Penn State Health Milton S. Hershey Medical Center Hershey Pennsylvania 17033 —
Perelman Center for Advanced Medicine Philadelphia Pennsylvania 19104 —
University of Pittsburgh Medical Center Pittsburgh Pennsylvania 15213 —
Medical University of South Carolina Charleston South Carolina 29425 —
Velocity Clinical Research Greenville South Carolina 29615 —
Lowcountry Lung and Critical Care PA North Charleston South Carolina 29406 —
Clinical Trials Center of Middle Tennessee Franklin Tennessee 37067 —
Statcare Pulmonary Consultants - Knoxville Knoxville Tennessee 37909 —
University of Tennessee Medical Center Knoxville Tennessee 37920 —
Vanderbilt University Medical Center Nashville Tennessee 37204 —
Baylor Scott and White Health - Advanced Lung Disease Specialists Dallas Texas 75246 —
El Paso Pulmonary Association El Paso Texas 79902 —
Baylor College of Medicine Houston Texas 77030 —
Research Centers of America McKinney Texas 75071 —
Renovatio Clinical Research The Woodlands Texas 77380 —
Topline Clinical Research Waxahachie Texas 75165 —
University of Utah Salt Lake City Utah 84108 —
University of Vermont Medical Center Burlington Vermont 05401 —
INOVA Fairfax Medical Campus Falls Church Virginia 22042 —
Western Washington Medical Group Everett Washington 98208 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 189 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06097260, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 5, 2026 · Synced Oct 14, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT06097260 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →