ClinicalTrials.gov record
A Study of mRNA-1083 (SARS-CoV-2 and Influenza) Vaccine in Healthy Adult Participants, ≥50 Years of Age
ClinicalTrials.gov ID: NCT06097273
Public ClinicalTrials.gov record NCT06097273. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Observer-Blind, Active-Control Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1083 (SARS-CoV-2 and Influenza) Vaccine in Healthy Adult Participants, ≥50 Years of Age
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the immunogenicity, safety, and reactogenicity of mRNA-1083 as compared with active control, co-administered licensed influenza and severe acute respiratory syndrome coronavirus 2 (SARS CoV 2) vaccines, in 2 independent age-group sub-study cohorts, healthy adults 65 years and older (Cohort A) and healthy adults 50 to \<65 years of age (Cohort B).
Study identification
- NCT ID
- NCT06097273
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 8,061 participants
Conditions and interventions
Conditions
Interventions
- mRNA-1083 Biological
- Placebo Biological
- Influenza Vaccine Biological
- COVID-19 Vaccine Biological
Biological
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Accepts healthy volunteers
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Oct 19, 2023 (Actual)
- Primary completion
- May 28, 2024 (Actual)
- Completion
- May 28, 2024 (Actual)
- Last update posted
- Jul 1, 2025
2023 – 2024
United States locations
- U.S. sites
- 146
- U.S. states
- 35
- U.S. cities
- 125
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Pinnacle Research Group-409 E 10th St | Anniston | Alabama | 36207-4780 | — |
| Accel Research Site - Achieve - Birmingham | Birmingham | Alabama | 35216 | — |
| Cullman Clinical Trials | Cullman | Alabama | 35055-1902 | — |
| Desert Clinical Research - CCT - PPDS | Mesa | Arizona | 85213-5226 | — |
| Foothills Research Center - CCT - PPDS | Phoenix | Arizona | 85044-6097 | — |
| Headlands Research - Scottsdale - PPDS | Scottsdale | Arizona | 85260-6411 | — |
| Scottsdale Clinical Trials | Scottsdale | Arizona | 85260-6742 | — |
| Fiel Family & Sports Medicine - PC - CCT - PPDS | Tempe | Arizona | 85283-1528 | — |
| AES - DRS - Synexus Clinical Research US, Inc. - Cerritos | Cerritos | California | 90703-2544 | — |
| Long Beach Research Institute, LLC | Long Beach | California | 90805-4587 | — |
| CenExel Apex (CNS) - Los Alamitos - PPDS | Los Alamitos | California | 90720-3118 | — |
| Central Valley Research, LLC | Modesto | California | 95350-5365 | — |
| Carbon Health- NoHo West Urgent Care and Primary Care | North Hollywood | California | 91606-3287 | — |
| Empire Clinical Research | Pomona | California | 91767-1800 | — |
| Artemis Institute For Clinical Research LLC - Riverside - Headlands - PPDS | Riverside | California | 92503-4955 | — |
| Clinical Innovations Trials - Riverside - CenExel - PPDS | Riverside | California | 92506-3257 | — |
| Peninsula Research Associates - Headlands - PPDS | Rolling Hills Estates | California | 90274-7604 | — |
| Artemis Institute For Clinical Research LLC - San Diego - Headlands - PPDS | San Diego | California | 92103-2204 | — |
| AES - DRS - Synexus Clinical Research US, Inc. - Vista | Vista | California | 92083-6051 | — |
| Tekton Research - Fort Collins - PPDS | Fort Collins | Colorado | 80525-5752 | — |
| Tekton Research - Longmont - PPDS | Longmont | Colorado | 80501-6461 | — |
| Stamford Therapeutics Consortium - ERN - PPDS | Stamford | Connecticut | 06905-5316 | — |
| Chase Medical Research LLC - Waterbury | Waterbury | Connecticut | 06708-3346 | — |
| Revival Research Corporation | Doral | Florida | 33122-1902 | — |
| Indago Research and Health Center | Hialeah | Florida | 33012 | — |
| CenExel RCA - Hollywood | Hollywood | Florida | 33024-2709 | — |
| Nature Coast Clinical Research | Inverness | Florida | 34452 | — |
| Jacksonville Center For Clinical Research | Jacksonville | Florida | 32216 | — |
| Health Awareness - Jupiter - ERN - ERN | Jupiter | Florida | 33458-2775 | — |
| Accel Research Sites - Saint Petersburg - Largo - ERN - PPDS | Largo | Florida | 33777-1359 | — |
| Flourish Research - Leesburg - PPDS | Leesburg | Florida | 34748-5077 | — |
| Accel Research Sites - Maitland | Maitland | Florida | 32751-7258 | — |
| AES - DRS - Optimal Research Florida - Melbourne | Melbourne | Florida | 32934-8172 | — |
| Suncoast Research Group LLC - Flourish - PPDS | Miami | Florida | 33135-1687 | — |
| St. Johns Center for Clinical Research - ERN - PPDS | Saint Augustine | Florida | 32086-5775 | — |
| ForCare Clinical Research - CenExel FCR - PPDS | Tampa | Florida | 33613-1244 | — |
| AES - DRS - Synexus Clinical Research US, Inc. - Atlanta | Atlanta | Georgia | 30328-4018 | — |
| DelRicht Research, LLC - Springer Wellness & Restorative - Atlanta - PPDS | Atlanta | Georgia | 30329-2201 | — |
| iResearch Atlanta - CenExel - PPDS | Decatur | Georgia | 30030-3438 | — |
| Javara, Inc./Privia Medical Group Georgia, LLC - Fayetteville - Javara - PPDS | Fayetteville | Georgia | 30214 | — |
| Georgia Clinic - CCT - PPDS | Norcross | Georgia | 30092-4544 | — |
| Privia Medical Group Georgia, LLC - Savannah - Javara - PPDS | Savannah | Georgia | 31406-3928 | — |
| Clinical Research Atlanta - ERN - PPDS | Stockbridge | Georgia | 30281-9054 | — |
| AES - DRS - Synexus Clinical Research US, Inc. - Chicago | Chicago | Illinois | 60602-3960 | — |
| Cedar Crosse Research Center | Chicago | Illinois | 60607-4559 | — |
| Flourish Research - Andersonville - PPDS | Chicago | Illinois | 60640-2781 | — |
| Koch Family Medicine | Morton | Illinois | 61550-2495 | — |
| AES - DRS - Optimal Research Illinois - Peoria | Peoria | Illinois | 61614 | — |
| DM Clinical Research - Chicago - ERN - PPDS | River Forest | Illinois | 60305-1876 | — |
| AES - DRS - Synexus Clinical Research US, Inc. - Evansville | Evansville | Indiana | 47714-7513 | — |
| Velocity Clinical Research - Valparaiso (Buynak Clinical Research) - PPDS | Valparaiso | Indiana | 46383-2195 | — |
| The Iowa Clinic, P.C. - West Des Moines Campus | West Des Moines | Iowa | 50266-8216 | — |
| Johnson County Clin-Trials | Lenexa | Kansas | 66219-1389 | — |
| Delricht Overland Park | Overland Park | Kansas | 66223-4857 | — |
| Tekton Research - Wichita - PPDS | Wichita | Kansas | 67218-2913 | — |
| DelRicht Research, LLC - Louisville - PPDS | Louisville | Kentucky | 40205-3162 | — |
| Versailles Family Medicine - CCT - PPDS | Versailles | Kentucky | 40383-1947 | — |
| Velocity Clinical Research (Baton Rouge - Louisiana) - PPDS | Baton Rouge | Louisiana | 70809-3416 | — |
| Velocity Clinical Research - Covington - PPDS | Covington | Louisiana | 70433-7237 | — |
| DelRicht Clinical Research, LLC - The Murphy Clinic - PPDS | Mandeville | Louisiana | 70471 | — |
| IMA Clinical Research - Monroe, LA - PPDS | Monroe | Louisiana | 71201-3915 | — |
| DelRicht Clinical Research, LLC - New Orleans - ClinEdge - PPDS | New Orleans | Louisiana | 70115-3584 | — |
| DelRicht Research, LLC - Internal - Baton Rouge - PPDS | Prairieville | Louisiana | 70769-4222 | — |
| Annapolis Internal Medicine - CCT - PPDS | Annapolis | Maryland | 21401-7050 | — |
| Advanced Primary Care & Geriatric Care - CCT - PPDS | Rockville | Maryland | 20850-6246 | — |
| DelRicht Clinical Research, LLC - Matthew Mintz, MD - PPDS | Rockville | Maryland | 20852-3803 | — |
| Velocity Clinical Research (Rockville - Maryland) - PPDS | Rockville | Maryland | 20854-2960 | — |
| Privia Medical Group, LLC - Columbia Pike - Silver Spring - Javara - PPDS | Silver Spring | Maryland | 20901-4402 | — |
| DM Clinical Research - The Brook House - ERN - PPDS | Brookline | Massachusetts | 02445-7113 | — |
| Headlands Research - Detroit - Headlands - PPDS | Southfield | Michigan | 48034-1088 | — |
| Great Lakes Research Institute | Southfield | Michigan | 48075-5400 | — |
| DM Clinical Research - Southfield - ERN - PPDS | Southfield | Michigan | 48076-5412 | — |
| Mankato Clinic - Premier Drive - Javara - PPDS | Mankato | Minnesota | 56001-6076 | — |
| AES - DRS - Synexus Clinical Research US, Inc. - Minneapolis | Richfield | Minnesota | 55423-2590 | — |
| DelRicht Research, LLC - Gulfport - PPDS | Gulfport | Mississippi | 39503-4176 | — |
| AES - DRS - Synexus Clinical Research US, Inc. - St. Louis | Creve Coeur | Missouri | 63141-7084 | — |
| Clay Platte Family Medicine - CCT Research | Kansas City | Missouri | 64151-2411 | — |
| Clinvest - National Ave - Headlands - PPDS | Springfield | Missouri | 65807-6012 | — |
| DelRicht Research, LLC - Command Family Medicine - Springfield - DelRicht - PPDS | Springfield | Missouri | 65807-7303 | — |
| Sundance Clinical Research - ERN - PPDS | St Louis | Missouri | 63141-7068 | — |
| DelRicht Clinical Research, LLC - MS. Medicine - PPDS | Town and Country | Missouri | 63017-8209 | — |
| Skyline Medical Center - PC - CCT - PPDS | Elkhorn | Nebraska | 68022-2889 | — |
| Methodist Physicians Clinic - CCT Research - PPDS | Fremont | Nebraska | 68025-2592 | — |
| Velocity Clinical Research (Lincoln - Nebraska) - PPDS | Lincoln | Nebraska | 68510-4855 | — |
| Velocity Clinical Research | Omaha | Nebraska | 68134 | — |
| Midwest Regional Health Services - LLC - CCT - PPDS | Omaha | Nebraska | 68144 | — |
| Papillion Research Center | Papillion | Nebraska | 68046-4194 | — |
| AES - DRS - Synexus Clinical Research US, Inc. - Henderson | Henderson | Nevada | 89052-3992 | — |
| Santa Rosa Urgent Care - Primary Care - CCT - PPDS | Las Vegas | Nevada | 89119-5483 | — |
| Las Vegas Clinical Trials | North Las Vegas | Nevada | 89030-7187 | — |
| Hassman Research Institute - HRI - Berlin - CenExel - PPDS | Berlin | New Jersey | 08009 | — |
| Velocity Clinical Research - Albuquerque - PPDS | Albuquerque | New Mexico | 87107-4503 | — |
| AXCES Research Group - Sante Fe - ERN - PPDS | Santa Fe | New Mexico | 87505-4753 | — |
| DM Clinical Research - Brooklyn | Brooklyn | New York | 11220-5906 | — |
| AES - DRS - Synexus Clinical Research US, Inc. - New York | New York | New York | 10017-4008 | — |
| Rochester Clinical Research, Inc | Rochester | New York | 14609-3173 | — |
| DelRicht Research, LLC - Charlotte - PPDS | Charlotte | North Carolina | 28205-5078 | — |
| Tryon Medical Partners, PLLC and Javara Inc. - Javara - PPDS | Charlotte | North Carolina | 28287-3884 | — |
| Monroe Biomedical Research -343 Venus St | Monroe | North Carolina | 28112-4025 | — |
| Trial Management Associates LLC - ERN - PPDS | Wilmington | North Carolina | 28403-6235 | — |
| CTI Clinical Research Center - PPDS | Cincinnati | Ohio | 45212 | — |
| Velocity Clinical Research (Cincinnati - Ohio) - PPDS | Cincinnati | Ohio | 45219-2975 | — |
| AES - DRS - Synexus Clinical Research US, Inc. - Cincinnati | Cincinnati | Ohio | 45236-3669 | — |
| Velocity Clinical Research (Cincinnati - Ohio) - PPDS | Cincinnati | Ohio | 45246-2316 | — |
| AES - DRS - Synexus Clinical Research US, Inc. - Columbus | Columbus | Ohio | 43212-3119 | — |
| WellNow Urgent Care & Research - Huber Heights | Huber Heights | Ohio | 45424-4019 | — |
| Tekton Research - Edmond - PPDS | Edmond | Oklahoma | 73013-5478 | — |
| Lynn Institute of East Oklahoma - ERN - PPDS | Oklahoma City | Oklahoma | 73111-3324 | — |
| DelRicht Research, LLC - Internal - Tulsa - PPDS | Tulsa | Oklahoma | 74133-8902 | — |
| Tekton Research - Yukon - PPDS | Yukon | Oklahoma | 73099-9518 | — |
| The Corvallis Clinic, PC - 3680 NW Samaritan Drive | Corvallis | Oregon | 97330-3737 | — |
| Hatboro Medical Associates - CCT - PPDS | Hatboro | Pennsylvania | 19040-2045 | — |
| DM Clinical Research - Philadelphia - ERN - PPDS | Philadelphia | Pennsylvania | 19107-1530 | — |
| AES - DRS - Synexus Clinical Research US, Inc. - Anderson | Anderson | South Carolina | 29621-2062 | — |
| TMA - Myrtle Beach - ERN - PPDS | Myrtle Beach | South Carolina | 29572-4610 | — |
| Velocity Clinical Research - Spartanburg - PPDS | Spartanburg | South Carolina | 29303-4225 | — |
| DelRicht Research, LLC - Hendersonville - PPDS | Hendersonville | Tennessee | 37075-8947 | — |
| AES - DRS - Optimal Research Texas - Austin | Austin | Texas | 78705-2655 | — |
| Benchmark Research - Austin - HyperCore - PPDS | Austin | Texas | 78705-3298 | — |
| Tekton Research - Austin - PPDS | Austin | Texas | 78745 | — |
| Tekton Research Inc | Beaumont | Texas | 77706-3061 | — |
| Headlands Research - Brownsville - Headlands - PPDS | Brownsville | Texas | 78526-4332 | — |
| AES - DRS - Synexus Clinical Research US, Inc. - Dallas | Dallas | Texas | 75234-7858 | — |
| 3A Research, LLC | El Paso | Texas | 79925 | — |
| Privia Medical Group- North Texas - West Parker Road - Fort Worth - Javara - PPDS | Fort Worth | Texas | 76133-4953 | — |
| Mount Olympus Medical Research Group - ClinEdge - PPDS | Friendswood | Texas | 77546 | — |
| DM Clinical Research - Cyfair Clinical Research Center - ERN - PPDS | Houston | Texas | 77065-5685 | — |
| DM Clinical Research - Bellaire - ERN - PPDS | Houston | Texas | 77081-4648 | — |
| DM Clinical Research - Texas Center for Drug Development - Humble - ERN - PPDS | Humble | Texas | 77338-4205 | — |
| DelRicht Research, LLC - Zomnir Family Medicine - DelRicht - PPDS | McKinney | Texas | 75070-8481 | — |
| Benchmark Research - San Angelo - HyperCore - PPDS | San Angelo | Texas | 76904-7610 | — |
| Sun Research Institute -427 9th St | San Antonio | Texas | 78215-1528 | — |
| Clinical Trials of Texas, Inc. - PPDS | San Antonio | Texas | 78229-3539 | — |
| IMA Clinical Research - San Antonio - PPDS | San Antonio | Texas | 78229 | — |
| Tekton Research - San Antonio - PPDS | San Antonio | Texas | 78229 | — |
| Privia Medical Group Gulf Coast, PLLC - San Marcos - Javara - PPDS | San Marcos | Texas | 78666-9734 | — |
| Privia Medical Group- North Texas - Stephenville - Javara - PPDS | Stephenville | Texas | 76401-1860 | — |
| DM Clinical Research - Sugarland - ERN - PPDS | Sugar Land | Texas | 77478-4913 | — |
| DM Clinical Research - ERN - PPDS | Tomball | Texas | 77375-3330 | — |
| Cope Family Medicine - CCT - PPDS | Bountiful | Utah | 84010-4862 | — |
| Ogden Clinic - Mountain View - CCT - PPDS | Pleasant View | Utah | 84404-4791 | — |
| Ogden Clinic - Grandview - CCT - PPDS | Roy | Utah | 84067-9438 | — |
| JBR Clinical Research - CenExel JBR - PPDS | Salt Lake City | Utah | 84107-4536 | — |
| AES - DRS - Synexus Clinical Research US, Inc. - Salt Lake City | South Salt Lake | Utah | 84106-1466 | — |
| Velocity Clinical Research - Family Practice - Portsmouth - PPDS | Portsmouth | Virginia | 23703-3200 | — |
| Wenatchee Valley Hospital & Clinics Campus | Wenatchee | Washington | 98801-2028 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06097273, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Jul 1, 2025 · Synced Oct 28, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06097273 live on ClinicalTrials.gov.