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Active, not recruiting Phase 2 Interventional Accepts healthy volunteers

Study of Lenacapavir and Emtricitabine/Tenofovir Disoproxil Fumarate (F/TDF) in Prevention of HIV in Cisgender Women in the United States (HPTN 102)

ClinicalTrials.gov ID: NCT06101329

Public ClinicalTrials.gov record NCT06101329. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Jun 26, 2026, 4:44 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Open-label, Multicenter, Randomized Study to Evaluate the Pharmacokinetics, Safety, and Acceptability of Twice Yearly Long-acting Subcutaneous Lenacapavir for Pre-Exposure Prophylaxis in Cisgender Women in the United States

Study identification

NCT ID
NCT06101329
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
Gilead Sciences
Industry
Enrollment
253 participants

Conditions and interventions

Interventions

  • Lenacapavir Tablet Drug
  • Lenacapavir Injection Drug
  • Emtricitabine/Tenofovir Disoproxil Fumarate (F/TDF) Drug

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
Female
Healthy volunteers
Accepts healthy volunteers

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 16, 2023
Primary completion
Jun 30, 2026
Completion
Dec 31, 2027
Last update posted
Sep 22, 2025

2023 – 2028

United States locations

U.S. sites
11
U.S. states
9
U.S. cities
10
Facility City State ZIP Site status
UAB, 1917 Research Clinic Birmingham Alabama 35222
UCSD Antiviral Research Center (AVRC) San Diego California 92103
George Washington University Medical Faculty Associates Washington D.C. District of Columbia 20037
Ponce de Leon Center Clinical Research Site Atlanta Georgia 30303
Fenway Health Boston Massachusetts 02215
Rutgers New Jesey Medical School - Clinical Research Center Newark New Jersey 07103
Cornell Clinical Trials Unit, New York Presbyterian Hospital - Weill Cornell Medicine New York New York 10010
Harlem Prevention Center CRS New York New York 10027
ICAP at Columbia University - Bronx Prevention Center The Bronx New York 10451
NC TraCS Institute - CTRC; University of North Carolina at Chapel Hill Chapel Hill North Carolina 27599
Penn Prevention Research Unit Philadelphia Pennsylvania 19104

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06101329, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Sep 22, 2025 · Synced Jun 26, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06101329 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →