A Study About How Well TAK-279 Works and Its Safety in Participants With Moderate-to-severe Plaque Psoriasis During 60 Weeks of Treatment With a Withdrawal and Retreatment Period
Public ClinicalTrials.gov record NCT06108544. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3, Randomized, Multicenter, Double-Blind, Placebo- and Active Comparator-Controlled Study With a Randomized Withdrawal and Retreatment Period to Evaluate the Efficacy, Safety, and Tolerability of TAK-279 in Subjects With Moderate-to-Severe Plaque Psoriasis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main aim of this study is to show how well TAK-279 reduces the skin plaques compared to placebo, in participants with moderate-to-severe plaque psoriasis. Participants will be assigned to one of the 3 study treatments (TAK-279, apremilast (an approved treatment), or a placebo). Participants will be in the study for up to 69 weeks.
Study identification
- NCT ID
- NCT06108544
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 1,108 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 6, 2023 (Actual)
- Primary completion
- Dec 6, 2024 (Actual)
- Completion
- Nov 7, 2025 (Actual)
- Last update posted
- Nov 20, 2025
2023 – 2025
United States locations
- U.S. sites
- 66
- U.S. states
- 26
- U.S. cities
- 57
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Total Dermatology | Birmingham | Alabama | 35205 | — |
| Cahaba Dermatology Skin Health Center | Hoover | Alabama | 35244-2111 | — |
| Medical Dermatology Specialists | Phoenix | Arizona | 85006-2722 | — |
| Noble Clinical Research | Tucson | Arizona | 85704-7892 | — |
| Johnson Dermatology Clinic | Fort Smith | Arkansas | 72916-6103 | — |
| Burke Pharmaceutical Research | Hot Springs | Arkansas | 71913-6475 | — |
| Zenith Research, Inc. | Beverly Hills | California | 90211-1705 | — |
| UNISON Clinical Trials (Shahram Jacobs md inc.) | Encino | California | 91436-2428 | — |
| First OC Dermatology Research Inc. | Fountain Valley | California | 92708-3701 | — |
| Long Beach Research Institute, LLC | Long Beach | California | 90805-4587 | — |
| Metropolis Dermatology Downtown LA - Probity - PPDS | Los Angeles | California | 90017-5310 | — |
| Northridge Clinical Trials | Northridge | California | 91325-4122 | — |
| TCR Medical Corporation | San Diego | California | 92123-1523 | — |
| University Clinical Trials | San Diego | California | 92123 | — |
| Dermatology Institute and Skin Care Center | Santa Monica | California | 90404-2216 | — |
| Revival Research Corporation - Florida - ClinEdge - PPDS | Doral | Florida | 33122-1902 | — |
| Florida Academic Centers Research | Miami | Florida | 33136-1003 | — |
| San Marcus Research Clinic Inc | Miami Lakes | Florida | 33014-5602 | — |
| FXM Research Miramar | Miramar | Florida | 33027-4714 | — |
| Lenus Research & Medical Group | Sweetwater | Florida | 33172-2741 | — |
| Advanced Clinical Research Institute (ACRI) - Florida | Tampa | Florida | 33607-6429 | — |
| Olympian Clinical Research - 6331 Memorial Hwy | Tampa | Florida | 33615 | — |
| Divine Dermatology and Aesthetics, LLC | Atlanta | Georgia | 30315-2042 | — |
| Advanced Medical Research, PC | Atlanta | Georgia | 30342-1418 | — |
| Skin Care Physicians of Georgia | Macon | Georgia | 31217-3861 | — |
| NorthShore Medical Group Dermatology - Skokie | Skokie | Illinois | 60077-1049 | — |
| DS Research - 1005 E. Lewis & Clark Pkwy Indiana Location | Clarksville | Indiana | 47129-2201 | — |
| Skin Sciences, PLLC | Louisville | Kentucky | 40217-1444 | — |
| DS Research of Kentucky | Louisville | Kentucky | 40241-6162 | — |
| Dermatology & Advanced Aesthetics | Lake Charles | Louisiana | 70605-1213 | — |
| Lawrence J Green, MD LLC | Rockville | Maryland | 20850-6363 | — |
| Allcutis Research LLC | Beverly | Massachusetts | 01915 | — |
| Beacon Clinical Research LLC | Brockton | Massachusetts | 02301 | — |
| David Fivenson MD Dermatology PLLC | Ann Arbor | Michigan | 48103-9746 | — |
| University of Michigan Hospital - 1500 E Medical Center Dr | Ann Arbor | Michigan | 48109-5360 | — |
| Oakland Hills Dermatology - 3400 Auburn Rd | Auburn Hills | Michigan | 48326-3396 | — |
| Minnesota Clinical Study Center | Fridley | Minnesota | 55432-3134 | — |
| Skin Specialists PC | Omaha | Nebraska | 68144 | — |
| Vivida Dermatology - Flamingo Rd - Probity - PPDS | Las Vegas | Nevada | 89119-5190 | — |
| ALLCUTIS Research, LLC. | Portsmouth | New Hampshire | 03801-03804 | — |
| Psoriasis Treatment Center of Central New Jersey | East Windsor | New Jersey | 08520 | — |
| Mount Sinai Doctors -234 E 85th St | New York | New York | 10029-6504 | — |
| Sadick Research Group | New York | New York | 10075-0385 | — |
| Derm Research Center of NY | Stony Brook | New York | 11790 | — |
| Montefiore Dermatology - BRANY - PPDS | The Bronx | New York | 10467-1402 | — |
| Duke Dermatology Clinic | Durham | North Carolina | 27710-4000 | — |
| The Skin Surgery Center for Clinical Research - Objective Health - PPDS | Winston-Salem | North Carolina | 27103-7109 | — |
| Wake Forest Baptist Health Department of Dermatology - 4618 Country Club Rd | Winston-Salem | North Carolina | 27157-0001 | — |
| ClinOhio Research Services | Columbus | Ohio | 43213-4445 | — |
| Wright State Physicians | Fairborn | Ohio | 45324 | — |
| Apex Clinical Research Center | Mayfield Heights | Ohio | 44124-4005 | — |
| Oregon Medical Research Center PC | Portland | Oregon | 97239-4501 | — |
| University of Pittsburgh Medical Center-3601 5th Ave | Pittsburgh | Pennsylvania | 15213-3403 | — |
| Cumberland Skin Center for Clinical Research - Objective Health - PPDS | Hermitage | Tennessee | 37076-3497 | — |
| Tennessee Clinical Research Center | Nashville | Tennessee | 37215-2888 | — |
| Arlington Research Center | Arlington | Texas | 76011-3800 | — |
| UT Physicians Dermatology - Bellaire Station | Bellaire | Texas | 77401-3535 | — |
| Modern Research Associates | Dallas | Texas | 75231-6077 | — |
| North Texas Center for Clinical Research | Frisco | Texas | 75034 | — |
| Austin Institute for Clinical Research, Inc. - Pflugerville - ClinEdge - PPDS | Pflugerville | Texas | 78660-6148 | — |
| Texas Dermatology and Laser Specialists | San Antonio | Texas | 78218-3128 | — |
| Dermatology Clinical Research Center of San Antonio | San Antonio | Texas | 78229-3409 | — |
| Houston Center for Clinical Research, LLC | Sugar Land | Texas | 77479-1001 | — |
| Center For Clinical Studies, LTD. LLP - 451 N Texas Ave | Webster | Texas | 77598-4927 | — |
| Center For Clinical Studies,LTD. LLP - 451 N Texas Ave | Webster | Texas | 77598-4927 | — |
| Virginia Clinical Research - 6160 Kempsville Cir | Norfolk | Virginia | 23507 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 151 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06108544, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Nov 20, 2025 · Synced Oct 23, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06108544 live on ClinicalTrials.gov.