Study to Assess the Efficacy & Safety of KHK4951 in Patients With Neovascular Age-Related Macular Degeneration
Public ClinicalTrials.gov record NCT06116890. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Multicenter, Randomized, Double-Masked, Parallel Group Study to Assess the Efficacy and Safety of KHK4951, a Vascular Endothelial Growth Factor Receptor Inhibitor, in Patients With Neovascular Age-Related Macular Degeneration
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate efficacy and safety of KHK4951 eye drops in patients with nAMD.
Study identification
- NCT ID
- NCT06116890
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 170 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 50 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 31, 2024 (Actual)
- Primary completion
- Jun 3, 2026 (Actual)
- Completion
- Jul 1, 2026 (Actual)
- Last update posted
- Oct 14, 2026
2024 – 2026
United States locations
- U.S. sites
- 38
- U.S. states
- 19
- U.S. cities
- 37
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Barnet Dulaney Perkins Eye Center - Phoenix | Mesa | Arizona | 85206 | — |
| Retina Associates Southwest, P.C. | Tucson | Arizona | 85710 | — |
| Win Retina | Arcadia | California | 91006 | — |
| Retina Vitreous Associates Medical Group | Beverly Hills | California | 90211 | — |
| The Retina Partners | Encino | California | 91436 | — |
| Salehi Retina Institute, Inc | Huntington Beach | California | 92647 | — |
| Payam Amini | Pasadena | California | 91107 | — |
| Retina Consultants of Southern CO | Colorado Springs | Colorado | 80909 | — |
| Blue Ocean Clinical Research West | Clearwater | Florida | 33761 | — |
| Florida Eye Associates | Melbourne | Florida | 32901 | — |
| Eye Associates of Pinellas | Pinellas Park | Florida | 33782 | — |
| Ft. Lauderdale Eye Institute | Plantation | Florida | 33324 | — |
| Retina Vitreous Associates of Florida - Saint Petersburg | St. Petersburg | Florida | 33711 | — |
| Southern Vitreoretinal Associates | Tallahassee | Florida | 32308 | — |
| Center for Retina and Macular Disease - Ophthalmology | Winter Haven | Florida | 33880 | — |
| Southeast Retina Center | Augusta | Georgia | 30909 | — |
| Massachusetts Eye and Ear | Boston | Massachusetts | 02114 | — |
| Associated Retinal Consultants (ARC) P.C. - Opthalmology | Royal Oak | Michigan | 48073 | — |
| Sierra Eye Associates | Reno | Nevada | 89502 | — |
| Retina Center of New Jersey | Bloomfield | New Jersey | 07003 | — |
| Vision Research Center Eye Associates of New Mexico | Albuquerque | New Mexico | 87109 | — |
| Retina Vitreous Surgeons of Central NY, PC | Liverpool | New York | 13088 | — |
| Ophthalmic Consultants of Long Island | Oceanside | New York | 11572 | — |
| Retina Vitreous Center in Edmond Oklahoma | Edmond | Oklahoma | 73013 | — |
| Eye Health Northwest | Portland | Oregon | 97225 | — |
| Eye Care Specialists | Kingston | Pennsylvania | 18704 | — |
| Charleston Neuroscience Institute (RCA Network Site) | Ladson | South Carolina | 29456 | — |
| Black Hills Regional Eye Institute - Ophthalmology | Rapid City | South Dakota | 57701 | — |
| Charles Retina Institute | Germantown | Tennessee | 38138 | — |
| Retina Research Institute of Texas | Abilene | Texas | 79606 | — |
| Austin Retina Associates - Ophthalmology/Retina (RCA Network site) | Austin | Texas | 78705 | — |
| Austin Clinical Research, LLC | Austin | Texas | 78750 | — |
| Retina Consultants of Texas | Bellaire | Texas | 77401 | — |
| Texas Retina Associates | Fort Worth | Texas | 76104 | — |
| Retinal Consultants of Texas- San Antonio (RCA Network site) | San Antonio | Texas | 78240 | — |
| Retina Consultants of Texas (RCA Network Site) | The Woodlands | Texas | 77384 | — |
| Strategic Clinical Research Group, LLC | Willow Park | Texas | 76087 | — |
| Retina Group of Washington | Fairfax | Virginia | 22031 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 46 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06116890, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 14, 2026 · Synced Oct 19, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06116890 live on ClinicalTrials.gov.