ARTEMIS - A Research Study to Look at How Ziltivekimab Works Compared to Placebo in People With a Heart Attack
Public ClinicalTrials.gov record NCT06118281. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
ARTEMIS - Effects of Ziltivekimab Versus Placebo on Cardiovascular Outcomes in Patients With Acute Myocardial Infarction
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The research study is being done to see if ziltivekimab can be used to treat people who were admitted to hospital because of a heart attack. Ziltivekimab might reduce development of heart disease, thereby preventing new heart attacks or strokes. Participants will either get ziltivekimab (active medicine) or placebo (a dummy medicine which has no effect on the body). Which treatment participants get is decided by chance. The chance of getting ziltivekimab or placebo is the same. The participant will need to inject the study medicine into a flat skin surface in there stomach, thigh, or upper arm once every month. Ziltivekimab is not yet approved in any country or region in the world. It is a new medicine that doctors cannot prescribe. The study will last for about 2 years.
Study identification
- NCT ID
- NCT06118281
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 10,000 participants
Conditions and interventions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jun 25, 2024 (Actual)
- Primary completion
- Jan 29, 2027 (Estimated)
- Completion
- Jan 29, 2027 (Estimated)
- Last update posted
- Sep 9, 2026
2024 – 2027
United States locations
- U.S. sites
- 188
- U.S. states
- 43
- U.S. cities
- 159
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Advanced Cardiovascular, LLC | Alexander City | Alabama | 35010 | — |
| Birmingham VA Medical Center | Birmingham | Alabama | 35233 | — |
| Grandview Medical Center | Birmingham | Alabama | 35243 | — |
| Eastern Shore Rsrch Inst, LLC | Fairhope | Alabama | 36532 | — |
| Heart Center Rsrch_Hunstville | Huntsville | Alabama | 35801 | — |
| Mobile Heart USA Health Cardiology Clinic | Mobile | Alabama | 36606 | — |
| Mercy Gilbert Medical Center | Gilbert | Arizona | 85297 | — |
| Mayo Clinic Arizona | Phoenix | Arizona | 85054 | — |
| Honor Health | Scottsdale | Arizona | 85258 | — |
| Arkansas Cardiology Clinic | Little Rock | Arkansas | 72205 | — |
| Central Arkansas Veteran's Healthcare System | Little Rock | Arkansas | 72205 | — |
| Valley Clinical Trials | Covina | California | 91723 | — |
| UCSD Medical Center | La Jolla | California | 92037 | — |
| Loma Linda University Faculty Medical Clinics | Loma Linda | California | 92354 | — |
| VAGrtrLosAngelesHlthcareSystem | Los Angeles | California | 90073 | — |
| University of Californ LA-UCLA | Los Angeles | California | 90095 | — |
| University Of California Irvine | Orange | California | 92868-3201 | — |
| Kaiser Permanente Viewridge Medical Offices | San Diego | California | 92123 | — |
| San Diego Cardiac Center | San Diego | California | 92123 | — |
| San Francisco V.A. Medical Center | San Francisco | California | 94121 | — |
| LA BioMed Harbor UCLA Med Cenr | Torrance | California | 90502 | — |
| Torrance Memorial Medical Center | Torrance | California | 90505 | — |
| Interventional Cardiology Medical Group | West Hills | California | 91307 | — |
| University of CO - Division of Cardiology | Aurora | Colorado | 80045 | — |
| Denver Health Medical Center | Denver | Colorado | 80204 | — |
| Colorado Heart and Vascular PC | Golden | Colorado | 80401 | — |
| S Denver Cardiology Associates | Littleton | Colorado | 80120 | — |
| Advanced Heart & Vein Center | Thornton | Colorado | 80023 | — |
| Bridgeport Hospital | Bridgeport | Connecticut | 06610 | — |
| Danbury Hospital - Cardiology Department | Danbury | Connecticut | 06810 | — |
| Yale Ctr for Clin Invest | New Haven | Connecticut | 06519 | — |
| Cardiology Associates of Fairfield County | Stamford | Connecticut | 06905 | — |
| Christiana Care Health Services, Inc. | Newark | Delaware | 19718 | — |
| MedStar Hlth Res Institute | Washington D.C. | District of Columbia | 20010 | — |
| Holy Cross Hospital | Fort Lauderdale | Florida | 33308 | — |
| University of Florida | Gainesville | Florida | 32608 | — |
| Memorial Healthcare | Hollywood | Florida | 33021 | — |
| UF Hlth Jacksonville | Jacksonville | Florida | 32209 | — |
| Mayo Clinic Jacksonville | Jacksonville | Florida | 32224 | — |
| Baptist Heart Specialists | Jacksonville | Florida | 32258 | — |
| Baptist Hospital Cardiology | Pensacola | Florida | 32503 | — |
| Ascension Sacred Heart | Pensacola | Florida | 32504 | — |
| Intercoastal Medical Group | Sarasota | Florida | 34232 | — |
| Winter Haven Hospital | Winter Haven | Florida | 33881 | — |
| Emory University Hospital | Atlanta | Georgia | 30322-1059 | — |
| Augusta University | Augusta | Georgia | 30912 | — |
| Atlanta VAMC | Decatur | Georgia | 30033 | — |
| Northeast Georgia Medical Ctr | Gainesville | Georgia | 30501 | — |
| Cardio. Consult. of S. GA | Thomasville | Georgia | 31792 | — |
| St. Luke's Idaho Cardiology Associates | Meridian | Idaho | 83642 | — |
| Endeavor Health Glenbook Hosp | Evanston | Illinois | 60201 | — |
| OSF HealthCare_Cardiovasc Inst | Rockford | Illinois | 61107 | — |
| Prairie Cardiovascular Consultants, Ltd. | Springfield | Illinois | 62701 | — |
| Midwest Cardiovascu Rsrch Foundation | Elkhart | Indiana | 46514 | — |
| Indiana University Health Methodist Hospital | Indianapolis | Indiana | 46202 | — |
| Reid Physician Associates | Richmond | Indiana | 47374 | — |
| MercyOne NE Iowa Fam Med & Res | Waterloo | Iowa | 50702 | — |
| University Of Kansas Hospital | Kansas City | Kansas | 66160 | — |
| Midwest Heart and Vascular Specialists | Overland Park | Kansas | 66211 | — |
| Saint Elizabeth Medical Center | Edgewood | Kentucky | 41017 | — |
| University Of Louisville | Louisville | Kentucky | 40202 | — |
| University Medical Center New Orleans | New Orleans | Louisiana | 70112 | — |
| Overton Brooks V.A. Medical Center | Shreveport | Louisiana | 71101-4295 | — |
| Northern Light Eastern Maine Medical Center | Bangor | Maine | 04401 | — |
| Maine Medical Center Bramhall | Portland | Maine | 04102 | — |
| MedStar Hlth Res Institute | Clinton | Maryland | 20735 | — |
| Adventist HealthCare Shady Grove Medical Center | Rockville | Maryland | 20850 | — |
| Jadestone Clinical Research, LLC | Silver Spring | Maryland | 20904 | — |
| Brigham & Women's Hospital | Boston | Massachusetts | 02115 | — |
| McLaren Bay Region | Bay City | Michigan | 48708 | — |
| Wayne State University/University Health Center | Detroit | Michigan | 48201 | — |
| WMU Homer Stryker MD School of Medicine | Kalamazoo | Michigan | 49008 | — |
| McLaren Greater Lansing | Lansing | Michigan | 48910 | — |
| MidMic Medical Cntr - Midland | Midland | Michigan | 48670 | — |
| McLaren Macomb Health Care | Mount Clemens | Michigan | 48043 | — |
| McLaren Northern MI Hosp | Petoskey | Michigan | 49770 | — |
| Trinity Health Oakland Hospital | Pontiac | Michigan | 48341 | — |
| Corewell Health | Royal Oak | Michigan | 48073 | — |
| Ascension St. Mary's Research Institute - Michigan | Southfield | Michigan | 48075 | — |
| Trinity Health Michigan Heart | Ypsilanti | Michigan | 48197 | — |
| Essentia Health | Duluth | Minnesota | 55805 | — |
| Fairview Health Services | Maplewood | Minnesota | 55109 | — |
| Abbott Northwestern Hospital | Minneapolis | Minnesota | 55407 | — |
| VA Medical Center_Minneapolis | Minneapolis | Minnesota | 55417 | — |
| Regions Hospital | Saint Paul | Minnesota | 55101 | — |
| Jackson Heart Clinic | Jackson | Mississippi | 39216 | — |
| Univ of Mississippi Med Center | Jackson | Mississippi | 39216 | — |
| Cardiolg Assoc Rsch LLC_Tupelo | Tupelo | Mississippi | 38801 | — |
| North Mississippi Medical Center | Tupelo | Mississippi | 38801 | — |
| Missouri Cardiovascular Specialist | Columbia | Missouri | 65201 | — |
| North Kansas City Hospital | North Kansas City | Missouri | 64116 | — |
| Mercy Research | Springfield | Missouri | 65804 | — |
| Washington University School of Medicine_St. Louis | St Louis | Missouri | 63110 | — |
| Methodist Physicians Clinic | Omaha | Nebraska | 681114 | — |
| UMC of Southern Nevada | Las Vegas | Nevada | 89102 | — |
| Dartmouth-Hitchcock Med Ctr | Lebanon | New Hampshire | 03766 | — |
| Advanced Heart Care LLC | Bridgewater | New Jersey | 08807-3064 | — |
| Virtua Health | Camden | New Jersey | 08103 | — |
| Hackensack Meridian Health - Cardiovascular | Hackensack | New Jersey | 07601 | — |
| The Heart House Haddon Heights | Haddon Heights | New Jersey | 08035 | — |
| Jersey City Medical Center | Jersey City | New Jersey | 07302 | — |
| Inspira Health - Cardiology | Mullica Hill | New Jersey | 08062 | — |
| AtlantiCare Regional Medical Center | Pomona | New Jersey | 08240 | — |
| Holy Name Medical Center | Teaneck | New Jersey | 07666 | — |
| Heart House - Vineland | Vineland | New Jersey | 08360 | — |
| The New York Hospital | Brooklyn | New York | 11215 | — |
| Trinity Medical WNY, PC | Buffalo | New York | 14220 | — |
| Saint Joseph's Hospital Health Center | Liverpool | New York | 13088 | — |
| NYU Grossman School of Med | New York | New York | 10016 | — |
| Mount Sinai Morningside | New York | New York | 10025 | — |
| University of Rochester | Rochester | New York | 14642 | — |
| St Francis Hospital Lindner Research Center | Roslyn | New York | 11576 | — |
| Stony Brook University Hospital | Stony Brook | New York | 11794 | — |
| Jacobi Medical Center | The Bronx | New York | 10461 | — |
| Westchester Medical Center | Valhalla | New York | 10595 | — |
| Cardiology Associates_Asheville | Asheville | North Carolina | 28803 | — |
| UNC Hospital HVC_Meadowmont | Chapel Hill | North Carolina | 27599-7075 | — |
| Novant Hlth Vasc Ins Charlotte | Charlotte | North Carolina | 28204 | — |
| Duke University Medical Center | Durham | North Carolina | 27710 | — |
| Moses H. Cone Mem Hosp | Greensboro | North Carolina | 27401 | — |
| Wake Forest Uni Hlth Sciences | High Point | North Carolina | 27262 | — |
| NC Heart and Vascular Research | Raleigh | North Carolina | 27697 | — |
| Novant Hlth Cardio - Kimel Park | Winston-Salem | North Carolina | 27103 | — |
| Sanford Health - Fargo | Fargo | North Dakota | 58102 | — |
| Trinity Medical Group | Minot | North Dakota | 58701 | — |
| Aultman Hospital | Canton | Ohio | 44710 | — |
| Lindner Center,Christ Hospital | Cincinnati | Ohio | 45219 | — |
| University of Cincinnati/UC Health | Cincinnati | Ohio | 45241 | — |
| Louis Stokes Clvlnd VA Med Ctr | Cleveland | Ohio | 44106 | — |
| MetroHealth Medical Center | Cleveland | Ohio | 44109 | — |
| Cleveland Clinic_Cleveland | Cleveland | Ohio | 44195 | — |
| University Hospitals Of Cleveland Medical Center | Elyria | Ohio | 44035 | — |
| Wright State University | Fairborn | Ohio | 45324 | — |
| Kettering Medical Center | Kettering | Ohio | 45429 | — |
| ProMedica | Toledo | Ohio | 43606 | — |
| Mercy Health - St. Vincent Medical Center | Toledo | Ohio | 43608 | — |
| University of Toledo | Toledo | Ohio | 43614 | — |
| Genesis Health Care System | Zanesville | Ohio | 43701 | — |
| South Oklahoma Heart Research, LLC | Oklahoma City | Oklahoma | 73135 | — |
| Penn State Hlth Holy Spirit Med Ctr | Camp Hill | Pennsylvania | 17011 | — |
| Chambersburg Hospital | Chambersburg | Pennsylvania | 17201 | — |
| Geisinger Medical Center | Danville | Pennsylvania | 17822 | — |
| Penn State Hershey Medical Center | Hershey | Pennsylvania | 17033 | — |
| Robert Packer Hospital | Sayre | Pennsylvania | 18840 | — |
| Reading Hospital | West Reading | Pennsylvania | 19611 | — |
| Rhode Island Hospital | Providence | Rhode Island | 02903 | — |
| AnMed Health Clinical Research | Anderson | South Carolina | 29621 | — |
| Prism Hlth Carolina Card Cons | Greenville | South Carolina | 29605 | — |
| Monument Health Clinical Rsrch | Rapid City | South Dakota | 57701 | — |
| Sanford Research | Sioux Falls | South Dakota | 57105 | — |
| Chattanooga Heart Institute | Chattanooga | Tennessee | 37404 | — |
| Knoxville Heart Group | Knoxville | Tennessee | 37916 | — |
| Tennova HC Turkey Creek MC | Knoxville | Tennessee | 37934 | — |
| Baptist Clin Res Institute | Memphis | Tennessee | 38120 | — |
| Saint Thomas Hospital | Nashville | Tennessee | 37205 | — |
| Vanderbilt University Medical Center | Nashville | Tennessee | 37232 | — |
| Parkway Cardiology Associates, PC | Oak Ridge | Tennessee | 37830 | — |
| CV Research of Knoxville | Powell | Tennessee | 37849 | — |
| PharmaTex Research, LLC | Amarillo | Texas | 79106 | — |
| Austin Heart | Austin | Texas | 78705 | — |
| Liver Ins@ Mthdist DTX Med Cen | Dallas | Texas | 75203 | — |
| Dallas VA Medical Center | Dallas | Texas | 75216 | — |
| University of Texas Southwestern Medical Center | Dallas | Texas | 75390-9302 | — |
| University of Texas Medical Branch | Galveston | Texas | 77555 | — |
| Houston Medical Center | Houston | Texas | 77004 | — |
| Houston Methodist Hospital | Houston | Texas | 77030 | — |
| Texas Heart Inst Medical Ctr | Houston | Texas | 77030 | — |
| UT Health University of Texas | Houston | Texas | 77030 | — |
| Prolato Clinical Research Cntr | Houston | Texas | 77054 | — |
| HCA Research Institute | McAllen | Texas | 78503-1299 | — |
| Heart & Vascular Inst._Titus | Mount Pleasant | Texas | 75455 | — |
| Baylor Scott & White Res Inst | Plano | Texas | 75093 | — |
| Methodist Healthcare System of San Antonio | San Antonio | Texas | 78229 | — |
| Christus Heart and Vascular Institute | Tyler | Texas | 75701 | — |
| Intermountain Medical Center | Murray | Utah | 84107-5701 | — |
| University of Virginia | Charlottesville | Virginia | 22908 | — |
| Inova Fairfax Medical Campus | Falls Church | Virginia | 22042 | — |
| Sentara Bayside Hospital | Norfolk | Virginia | 23507 | — |
| Chippenham Medical Center | Richmond | Virginia | 23225 | — |
| Bon Secours St. Mary's Hospital of Richmond, LLC | Richmond | Virginia | 23226 | — |
| McGuire VA Medical Center | Richmond | Virginia | 23249 | — |
| Virginia Commonwealth University Health System | Richmond | Virginia | 23298 | — |
| VA Medical Center_Salem | Salem | Virginia | 24153-6404 | — |
| Valley Health Link | Winchester | Virginia | 22601 | — |
| Swedish Medical Center_Seattle | Seattle | Washington | 98122-5789 | — |
| University Of Washington_Seattle | Seattle | Washington | 98195 | — |
| Multicare Health System | Tacoma | Washington | 98405 | — |
| Aurora St. Luke's Medi Ctr | Milwaukee | Wisconsin | 53215 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 648 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06118281, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 9, 2026 · Synced Oct 21, 2026
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Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06118281 live on ClinicalTrials.gov.