A Study of LY3305677 Compared With Placebo in Adult Participants With Obesity or Overweight
Public ClinicalTrials.gov record NCT06124807. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Parallel-Group, Double-Blind, 4-Arm Study to Investigate Weight Management With LY3305677 Compared With Placebo and in Adult Participants With Obesity or Overweight
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The main purpose of this study, performed under a master protocol W8M-MC-CWMM (NCT06143956), is to investigate weight management efficacy and safety with Mazdutide compared with placebo and in adult participants with obesity or overweight. The study will last about 62 weeks.
Study identification
- NCT ID
- NCT06124807
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 179 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years to 75 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 16, 2023
- Primary completion
- Jan 21, 2025
- Completion
- Jul 8, 2025
- Last update posted
- Apr 20, 2026
2023 – 2025
United States locations
- U.S. sites
- 29
- U.S. states
- 17
- U.S. cities
- 28
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| The Institute for Liver Health II dba Arizona Clinical Trials - Mesa | Chandler | Arizona | 85225 | — |
| Headlands Research - Scottsdale | Scottsdale | Arizona | 85260 | — |
| The Institute for Liver Health II dba Arizona Liver Health-Tucson | Tucson | Arizona | 85712 | — |
| Velocity Clinical Research, Huntington Park | Huntington Park | California | 90255 | — |
| Peninsula Research Associates | Rolling Hills Estates | California | 90274 | — |
| Diablo Clinical Research, Inc. | Walnut Creek | California | 94598 | — |
| Northeast Research Institute (NERI) | Fleming Island | Florida | 32003 | — |
| Suncoast Clinical Research, Inc. | New Port Richey | Florida | 34652 | — |
| Charter Research - Winter Park | Orlando | Florida | 32803 | — |
| Charter Research - Lady Lake | The Villages | Florida | 32162 | — |
| Pacific Diabetes & Endocrine Center | Honolulu | Hawaii | 96817 | — |
| Great Lakes Clinical Trials - Andersonville | Chicago | Illinois | 60640 | — |
| Great Lakes Clinical Trials - Ravenswood | Chicago | Illinois | 60640 | — |
| Cotton O'Neil Diabetes & Endocrinology | Topeka | Kansas | 66606 | — |
| L-MARC Research Center | Louisville | Kentucky | 40213 | — |
| Knownwell | Needham | Massachusetts | 02492 | — |
| StudyMetrix Research | City of Saint Peters | Missouri | 63303 | — |
| Las Vegas Medical Research | Las Vegas | Nevada | 89128 | — |
| Dent Neurologic Institute | Amherst | New York | 14226 | — |
| North Suffolk Neurology | Port Jefferson Station | New York | 11776 | — |
| Lucas Research, Inc. | New Bern | North Carolina | 28562 | — |
| CTI Clinical Research Center | Cincinnati | Ohio | 45212 | — |
| Quality Medical Research | Nashville | Tennessee | 37211 | — |
| IMA Clinical Research Austin | Austin | Texas | 78745 | — |
| Velocity Clinical Research, Dallas | Dallas | Texas | 75230 | — |
| PlanIt Research, PLLC | Houston | Texas | 77079 | — |
| Tekton Research - Fredericksburg Road | San Antonio | Texas | 78229 | — |
| Spectrum Medical, Inc. | Danville | Virginia | 24541 | — |
| Central Washington Health Services Association d/b/a Confluence Health | Wenatchee | Washington | 98801 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06124807, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Apr 20, 2026 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06124807 live on ClinicalTrials.gov.