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Completed Phase 2 Interventional Results available

A Study of LY3305677 Compared With Placebo in Adult Participants With Obesity or Overweight

ClinicalTrials.gov ID: NCT06124807

Public ClinicalTrials.gov record NCT06124807. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Oct 20, 2026, 5:56 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Parallel-Group, Double-Blind, 4-Arm Study to Investigate Weight Management With LY3305677 Compared With Placebo and in Adult Participants With Obesity or Overweight

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The main purpose of this study, performed under a master protocol W8M-MC-CWMM (NCT06143956), is to investigate weight management efficacy and safety with Mazdutide compared with placebo and in adult participants with obesity or overweight. The study will last about 62 weeks.

Study identification

NCT ID
NCT06124807
Recruitment status
Completed
Study type
Interventional
Phase
Phase 2
Lead sponsor
Eli Lilly and Company
Industry
Enrollment
179 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Nov 17, 2023 (Actual)
Primary completion
Jan 22, 2025 (Actual)
Completion
Jul 9, 2025 (Actual)
Last update posted
Apr 21, 2026

2023 – 2025

United States locations

U.S. sites
29
U.S. states
17
U.S. cities
28
Facility City State ZIP Site status
The Institute for Liver Health II dba Arizona Clinical Trials - Mesa Chandler Arizona 85225 —
Headlands Research - Scottsdale Scottsdale Arizona 85260 —
The Institute for Liver Health II dba Arizona Liver Health-Tucson Tucson Arizona 85712 —
Velocity Clinical Research, Huntington Park Huntington Park California 90255 —
Peninsula Research Associates Rolling Hills Estates California 90274 —
Diablo Clinical Research, Inc. Walnut Creek California 94598 —
Northeast Research Institute (NERI) Fleming Island Florida 32003 —
Suncoast Clinical Research, Inc. New Port Richey Florida 34652 —
Charter Research - Winter Park Orlando Florida 32803 —
Charter Research - Lady Lake The Villages Florida 32162 —
Pacific Diabetes & Endocrine Center Honolulu Hawaii 96817 —
Great Lakes Clinical Trials - Andersonville Chicago Illinois 60640 —
Great Lakes Clinical Trials - Ravenswood Chicago Illinois 60640 —
Cotton O'Neil Diabetes & Endocrinology Topeka Kansas 66606 —
L-MARC Research Center Louisville Kentucky 40213 —
Knownwell Needham Massachusetts 02492 —
StudyMetrix Research City of Saint Peters Missouri 63303 —
Las Vegas Medical Research Las Vegas Nevada 89128 —
Dent Neurologic Institute Amherst New York 14226 —
North Suffolk Neurology Port Jefferson Station New York 11776 —
Lucas Research, Inc. New Bern North Carolina 28562 —
CTI Clinical Research Center Cincinnati Ohio 45212 —
Quality Medical Research Nashville Tennessee 37211 —
IMA Clinical Research Austin Austin Texas 78745 —
Velocity Clinical Research, Dallas Dallas Texas 75230 —
PlanIt Research, PLLC Houston Texas 77079 —
Tekton Research - Fredericksburg Road San Antonio Texas 78229 —
Spectrum Medical, Inc. Danville Virginia 24541 —
Central Washington Health Services Association d/b/a Confluence Health Wenatchee Washington 98801 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06124807, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Apr 21, 2026 · Synced Oct 20, 2026

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Open the official record

The complete public registry record, listed eligibility criteria, and available contact information for NCT06124807 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →