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Active, not recruiting Phase 2 Interventional

A Study of Efficacy and Safety of Rosnilimab in Subjects With Moderate to Severe Ulcerative Colitis (ROSETTA)

ClinicalTrials.gov ID: NCT06127043

Public ClinicalTrials.gov record NCT06127043. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 2, 2026, 3:41 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Rosnilimab in Subjects With Moderate to Severe Ulcerative Colitis

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

ROSETTA STUDY: This study will evaluate the safety, tolerability, and efficacy of Rosnilimab in subjects with moderate to severe ulcerative colitis (UC)

Study identification

NCT ID
NCT06127043
Recruitment status
Active, not recruiting
Study type
Interventional
Phase
Phase 2
Lead sponsor
AnaptysBio, Inc.
Industry
Enrollment
132 participants

Conditions and interventions

Interventions

Drug

Eligibility (public fields only)

Age range
18 Years and older
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 3, 2023
Primary completion
Dec 31, 2025
Completion
Apr 30, 2026
Last update posted
Oct 2, 2025

2023 – 2026

United States locations

U.S. sites
25
U.S. states
12
U.S. cities
23
Facility City State ZIP Site status
AnaptysBio Investigational Site 10-115 Phoenix Arizona 85018
AnaptysBio Investigational Site 10-117 Garden Grove California 92845
AnaptysBio Investigational Site 10-112 Lancaster California 93534
AnaptysBio Investigational Site 10-129 Lancaster California 93534
AnaptysBio Investigational Site 10-108 San Jose California 95124
AnaptysBio Investigational Site 10-127 Brooksville Florida 34601
AnaptysBio Investigational Site 10-106 Miami Florida 33165
AnaptysBio Investigational Site 10-109 Miami Gardens Florida 33014
AnaptysBio Investigational Site 10-131 Orlando Florida 32789
AnaptysBio Investigational Site 10-123 Orlando Florida 32822
AnaptysBio Investigational Site 10-125 Tampa Florida 33607
AnaptysBio Investigational Site 10-122 Atlanta Georgia 30328
AnaptysBio Investigational Site 10-124 Oak Lawn Illinois 60453
AnaptysBio Investigational Site 10-118 Las Vegas Nevada 89128
AnaptysBio Investigational Site 10-133 Utica New York 13501
AnaptysBio Investigational Site 10-136 Cincinnati Ohio 45201
AnaptysBio Investigational Site 10-120 Norman Oklahoma 73017
AnaptysBio Investigational Site 10-103 Kingsport Tennessee 37663
AnaptysBio Investigational Site 10-104 Dallas Texas 75246
AnaptysBio Investigational Site 10-113 Garland Texas 75044
AnaptysBio Investigational Site 10-135 Georgetown Texas 78626
AnaptysBio Investigational Site 10-134 Lubbock Texas 79382
AnaptysBio Investigational Site 10-130 Southlake Texas 76092
AnaptysBio Investigational Site 10-132 Tyler Texas 75701
AnaptysBio Investigational Site 10-107 Seattle Washington 98195

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 75 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06127043, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Oct 2, 2025 · Synced Sep 2, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06127043 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →