A Research Study to See How Well CagriSema Compared to Tirzepatide Helps People With Obesity Lose Weight
Public ClinicalTrials.gov record NCT06131437. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
Efficacy and Safety of Cagrilintide 2.4 mg s.c. in Combination With Semaglutide 2.4 mg s.c. (CagriSema s.c. 2.4 mg/2.4 mg) Once-weekly Compared to Tirzepatide 15 mg s.c. Once-weekly in Participants With Obesity
Study identification
- NCT ID
- NCT06131437
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Novo Nordisk A/S
- Industry
- Enrollment
- 809 participants
Conditions and interventions
Conditions
Interventions
- Cagrilintide Drug
- Semaglutide Drug
- Tirzepatide Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Nov 26, 2023
- Primary completion
- Dec 7, 2025
- Completion
- Jan 8, 2026
- Last update posted
- Feb 5, 2026
2023 – 2026
United States locations
- U.S. sites
- 46
- U.S. states
- 22
- U.S. cities
- 42
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Univ of Alabama Birmingham | Birmingham | Alabama | 35294 | — |
| Chambliss Clinical Trials LLC | Montgomery | Alabama | 36106 | — |
| FDRC | Costa Mesa | California | 92627 | — |
| Diablo Clinical Research, Inc. | Walnut Creek | California | 94598 | — |
| Univ of Colorado at Denver | Aurora | Colorado | 80045 | — |
| Yale University School Of Medicine | New Haven | Connecticut | 06519 | — |
| Northeast Research Institute | Fleming Island | Florida | 32003 | — |
| Jacksonville Ctr For Clin Res | Jacksonville | Florida | 32216 | — |
| South Broward Research LLC | Miramar | Florida | 33027 | — |
| Hope Clin Res & Wellness | Conyers | Georgia | 30094 | — |
| East West Med Res Inst | Honolulu | Hawaii | 96814 | — |
| Great Lakes Clinical Trials | Chicago | Illinois | 60640 | — |
| Endeavor Health | Skokie | Illinois | 60077 | — |
| Evanston Premier Hlthcr Res | Skokie | Illinois | 60077 | — |
| Midwest Inst For Clin Res | Indianapolis | Indiana | 46260 | — |
| Northern Pines Hlth Ctr, PC | Buckley | Michigan | 49620 | — |
| StudyMetrix Research LLC | City of Saint Peters | Missouri | 63303 | — |
| Comprehensive Weight Ctrl Prog | New York | New York | 10021 | — |
| University of North Carolina | Chapel Hill | North Carolina | 27514 | — |
| Medication Mgmnt, LLC_Grnsboro | Greensboro | North Carolina | 27405 | — |
| PharmQuest Life Sciences LLC | Greensboro | North Carolina | 27408 | — |
| Accellacare_NC | Raleigh | North Carolina | 27609 | — |
| Accellacare | Wilmington | North Carolina | 28401 | — |
| New Venture Medical Research | Wadsworth | Ohio | 44281 | — |
| Lynn Institute of Norman | Norman | Oklahoma | 73072 | — |
| The University of Penn Center | Philadelphia | Pennsylvania | 19104-3317 | — |
| Clinical Res Collaborative | Cumberland | Rhode Island | 02864 | — |
| Medical University Of South Carolina | Charleston | South Carolina | 29425 | — |
| Coastal Carolina Res Ctr | North Charleston | South Carolina | 29405 | — |
| Hillcrest Clinical Research | Simpsonville | South Carolina | 29681-1538 | — |
| Spartanburg Medical Research | Spartanburg | South Carolina | 29303 | — |
| Holston Medical Group_Bristol | Bristol | Tennessee | 37620 | — |
| Holston Medical Group | Kingsport | Tennessee | 37660 | — |
| Amarillo Med Spec LLP | Amarillo | Texas | 79124 | — |
| Elligo Clin Res Centre | Austin | Texas | 78704 | — |
| UT Health University of Texas | Bellaire | Texas | 77401 | — |
| Baylr Sctt White Rs Inst, Endo | Dallas | Texas | 75226 | — |
| Velocity Clin Res, Dallas | Dallas | Texas | 75230 | — |
| UT Southwestern Medical Center-CRU | Dallas | Texas | 75390 | — |
| DCOL Ctr for Clin Res | Longview | Texas | 75605 | — |
| Washington Cntr Weight Mgmt | Arlington | Virginia | 22206 | — |
| Health Res of Hampton Roads | Newport News | Virginia | 23606 | — |
| National Clin Res Inc. | Richmond | Virginia | 23294 | — |
| Selma Medical Associates | Winchester | Virginia | 22601-3834 | — |
| Capital Clin Res Ctr,LLC | Olympia | Washington | 98502 | — |
| Rainier Clin Res Ctr Inc | Renton | Washington | 98057 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06131437, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 5, 2026 · Synced May 11, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06131437 live on ClinicalTrials.gov.