A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Vixarelimab in Participants With Moderate to Severe Ulcerative Colitis (UC)
Public ClinicalTrials.gov record NCT06137183. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase II, Multicenter Induction Study With an Active Treatment Extension to Evaluate the Efficacy, Safety, and Pharmacokinetics of Vixarelimab in Patients With Moderate to Severe Ulcerative Colitis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of this study is to evaluate the efficacy, safety, and pharmacokinetics (PK) of vixarelimab compared with placebo in participants with moderate to severe UC who have demonstrated inadequate response to, loss of response to, or intolerance to prior conventional or advanced therapy.
Study identification
- NCT ID
- NCT06137183
- Recruitment status
- Terminated
- Study type
- Interventional
- Phase
- Phase 2
- Enrollment
- 79 participants
Conditions and interventions
Conditions
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Apr 30, 2024
- Primary completion
- Jun 15, 2025
- Completion
- Jun 15, 2025
- Last update posted
- Feb 23, 2026
2024 – 2025
United States locations
- U.S. sites
- 15
- U.S. states
- 10
- U.S. cities
- 15
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| OM Research LLC - Camarillo - ClinEdge - PPDS | Camarillo | California | 93012 | — |
| UCLA Clinical and Translational Research Center | Los Angeles | California | 90095 | — |
| Facey Medical Foundation - Mission Hills | Mission Hills | California | 91345 1116 | — |
| Clinical Applications Laboratories, Inc. | San Diego | California | 92103-5639 | — |
| Sylvester Comprehensive Cancer Center | Miami | Florida | 33136 | — |
| Advanced Research Institute, Inc. | New Port Richey | Florida | 34653 | — |
| Orlando Gastroenterology, P.A. | Orlando | Florida | 32835 | — |
| Atlanta Gastroenterology Associates | Atlanta | Georgia | 30342 | — |
| Henry Ford Health System | Novi | Michigan | 48377 | — |
| Mayo Clinic - PPDS | Rochester | Minnesota | 55905 | — |
| Delta Gastroenterology & Endoscopy Center | Southaven | Mississippi | 38671 | — |
| Carolina Digestive Diseases | Greenville | North Carolina | 27834 | — |
| Gastro Intestinal Research Institute of Northern Ohio | Westlake | Ohio | 44145 | — |
| Tyler Research Institute, LLC | Tyler | Texas | 75701 | — |
| University of Utah - Health Sciences Center - PPDS | Salt Lake City | Utah | 84132 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 50 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06137183, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Feb 23, 2026 · Synced Sep 6, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06137183 live on ClinicalTrials.gov.