A Study of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis
Public ClinicalTrials.gov record NCT06143878. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 3 Multicenter, Randomized, Double-blind, Placebo-controlled and Deucravacitinib Active Comparator-controlled Study to Evaluate the Efficacy and Safety of JNJ-77242113 for the Treatment of Participants With Moderate to Severe Plaque Psoriasis
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The purpose of the study is to see how effective JNJ-77242113 is in participants with moderate to severe plaque psoriasis compared to placebo and deucravacitinib.
Study identification
- NCT ID
- NCT06143878
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Enrollment
- 774 participants
Conditions and interventions
Conditions
Interventions
- JNJ-77242113 Drug
- JNJ-77242113 Matching Placebo Drug
- Deucravacitinib Drug
- Deucravacitinib Matching Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 17, 2024 (Actual)
- Primary completion
- Sep 17, 2024 (Actual)
- Completion
- Jun 1, 2027 (Estimated)
- Last update posted
- Sep 28, 2026
2024 – 2027
United States locations
- U.S. sites
- 50
- U.S. states
- 25
- U.S. cities
- 48
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Medical Dermatology Specialists | Phoenix | Arizona | 85006 | — |
| Center for Dermatology and Plastic Surgery | Scottsdale | Arizona | 85260 | — |
| Johnson Dermatology | Fort Smith | Arkansas | 72916 | — |
| First OC Dermatology | Fountain Valley | California | 92708 | — |
| Center for Dermatology Clinical Research | Fremont | California | 94538 | — |
| Integrative Skin Science and Research | Sacramento | California | 95815 | — |
| Southern California Dermatology | Santa Ana | California | 92701 | — |
| Clinical Science Institute | Santa Monica | California | 90403 | — |
| Driven Research LLC | Miami | Florida | 33126 | — |
| Ziaderm Research LLC | North Miami Beach | Florida | 33162 | — |
| Renstar Medical Research | Ocala | Florida | 34470 | — |
| Forcare Clinical Research Inc | Tampa | Florida | 33613 | — |
| Hamilton Research LLC | Alpharetta | Georgia | 30022 | — |
| Skin Care Physicians of Georgia | Macon | Georgia | 31217 | — |
| DeNova Research | Chicago | Illinois | 60602 | — |
| Arlington Dermatology | Rolling Meadows | Illinois | 60008 | — |
| Endeavor Health | Skokie | Illinois | 60077 | — |
| Dundee Dermatology | West Dundee | Illinois | 60118 | — |
| Dawes Fretzin Clinical Research Group LLC | Indianapolis | Indiana | 46250 | — |
| Indiana Clinical Trial Center | Plainfield | Indiana | 46168 | — |
| Dermatology Specialists | Louisville | Kentucky | 40241 | — |
| Dermatology and Advanced Aesthetics | Lake Charles | Louisiana | 70605 | — |
| Tufts Medical Center | Boston | Massachusetts | 02111 | — |
| David Fivenson MD, Dermatology | Ann Arbor | Michigan | 48103 | — |
| Michigan Center of Medical Research | Clarkston | Michigan | 48346 | — |
| Henry Ford Medical Center | Detroit | Michigan | 48202 | — |
| Hamzavi Dermatology | Fort Gratiot | Michigan | 48059 | — |
| MediSearch Clinical Trials | Saint Joseph | Missouri | 64506 | — |
| Skin Specialists | Omaha | Nebraska | 68144 | — |
| Fife Dermatology | Las Vegas | Nevada | 89119 | — |
| StracSkin | Portsmouth | New Hampshire | 03801 | — |
| Schweiger Dermatology Group | East Windsor | New Jersey | 08520 | — |
| Schweiger Dermatology Group 1 | Hackensack | New Jersey | 07601 | — |
| Derm Research Center of New York, Inc. | Stony Brook | New York | 11790 | — |
| Wilmington Dermatology Center | Wilmington | North Carolina | 28405 | — |
| Oakview Dermatology | Athens | Ohio | 45701 | — |
| Optima Research | Boardman | Ohio | 44512 | — |
| Central Sooner Research | Oklahoma City | Oklahoma | 73170 | — |
| Oregon Medical Research Center | Portland | Oregon | 97201 | — |
| Health Concepts | Rapid City | South Dakota | 57702 | — |
| Modern Research Associates | Dallas | Texas | 75231 | — |
| Center for Clinical Studies 1 | Houston | Texas | 77004 | — |
| Austin Institute for Clinical Research 1 | Houston | Texas | 77056 | — |
| Austin Institute for Clinical Research | Pflugerville | Texas | 78660 | — |
| Progressive Clinical Research | San Antonio | Texas | 78213 | — |
| Texas Dermatology and Laser Specialists | San Antonio | Texas | 78218 | — |
| Center for Clinical Studies | Webster | Texas | 77598 | — |
| National Clinical Research | Richmond | Virginia | 23294 | — |
| Frontier Derm Partners CRO, LLC | Mill Creek | Washington | 98012 | — |
| Premier Clinical Research | Spokane | Washington | 99202 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 114 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06143878, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Sep 28, 2026 · Synced Oct 27, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete public registry record, listed eligibility criteria, and available contact information for NCT06143878 live on ClinicalTrials.gov.