A Study to Test an Oral Medicine, Belumosudil, in Combination With Corticosteroids in Participants at Least 12 Years of Age With Newly Diagnosed Chronic Graft Versus Host Disease.
Public ClinicalTrials.gov record NCT06143891. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Randomized, Double-blind, Multicenter, Phase 3 Study to Evaluate Efficacy and Safety of Belumosudil in Combination With Corticosteroids Versus Placebo in Combination With Corticosteroids in Participants at Least 12 Years of Age With Newly Diagnosed Chronic Graft Versus Host Disease (cGVHD)
Study identification
- NCT ID
- NCT06143891
- Recruitment status
- Active, not recruiting
- Study type
- Interventional
- Phase
- Phase 3
- Lead sponsor
- Sanofi
- Industry
- Enrollment
- 260 participants
Conditions and interventions
Conditions
Interventions
- Belumosudil Drug
- Placebo Drug
- Prednisone Drug
- Prednisolone Drug
Drug
Eligibility (public fields only)
- Age range
- 12 Years and older
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Jan 22, 2024
- Primary completion
- Sep 28, 2028
- Completion
- Sep 28, 2028
- Last update posted
- Oct 13, 2025
2024 – 2028
United States locations
- U.S. sites
- 24
- U.S. states
- 19
- U.S. cities
- 24
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| University of Arkansas for Medical Sciences-Site Number : 8400019 | Little Rock | Arkansas | 72205 | — |
| City of Hope National Medical Center- Site Number : 8400001 | Duarte | California | 91010 | — |
| University of California San Francisco - Parnassus Heights- Site Number : 8400035 | San Francisco | California | 94143 | — |
| AdventHealth Orlando- Site Number : 8400023 | Orlando | Florida | 32803 | — |
| The Hope Clinic of Emory University- Site Number : 8400020 | Decatur | Georgia | 30030 | — |
| Northwestern University- Site Number : 8400017 | Chicago | Illinois | 60611 | — |
| Indiana University Health University Hospital- Site Number : 8400006 | Indianapolis | Indiana | 46202 | — |
| University of Kentucky Chandler Medical Center- Site Number : 8400024 | Lexington | Kentucky | 40536 | — |
| Johns Hopkins Hospital- Site Number : 8400033 | Baltimore | Maryland | 21287 | — |
| Dana Farber Cancer Institute Site Number : 8400005 | Boston | Massachusetts | 02115 | — |
| Karmanos Cancer Institute - Detroit- Site Number : 8400013 | Detroit | Michigan | 48201 | — |
| UNC Children's Hospital- Site Number : 8400025 | Chapel Hill | North Carolina | 27514 | — |
| Atrium Health Wake Forest Baptist Medical Center - Winston-Salem - Medical Center Boulevard- Site Number : 8400007 | Winston-Salem | North Carolina | 27157 | — |
| Oncology Hematology Care - Kenwood- Site Number : 8400030 | Cincinnati | Ohio | 45236 | — |
| The Ohio State University Comprehensive Cancer Center (OSUCCC) - The James Cancer Hospital and Solove Research Institute- Site Number : 8400026 | Columbus | Ohio | 43210 | — |
| Oregon Health and Science University- Site Number : 8400027 | Portland | Oregon | 97239 | — |
| UPMC Hillman Cancer Center- Site Number : 8400008 | Pittsburgh | Pennsylvania | 15232 | — |
| Sarah Cannon Research Institute Site Number : 8400003 | Nashville | Tennessee | 37203 | — |
| St. David's South Austin Medical Center- Site Number : 8400002 | Austin | Texas | 78704 | — |
| Texas Oncology - Dallas - Worth Street- Site Number : 8400010 | Dallas | Texas | 75246 | — |
| Texas Transplant Institute - Methodist Hospital- Site Number : 8400037 | San Antonio | Texas | 78229 | — |
| University of Virginia Comprehensive Cancer Center-Site Number : 8400031 | Charlottesville | Virginia | 22903 | — |
| Fred Hutchinson Cancer Research Center- Site Number : 8400004 | Seattle | Washington | 98109 | — |
| University of Wisconsin Carbone Cancer Center-Site Number : 8400029 | Madison | Wisconsin | 53792 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 127 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06143891, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Oct 13, 2025 · Synced Jul 24, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06143891 live on ClinicalTrials.gov.