Cord Clamping Among Neonates With Congenital Heart Disease
Public ClinicalTrials.gov record NCT06153459. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
CORD-CHD: Clamp OR Delay Among Neonates With Congenital Heart Disease
Brief summary
Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.
The goal of this clinical trial is to compare 2 different timepoints for clamping the umbilical cord at birth for term-born infants with a prenatal diagnosis of congenital heart disease (CHD). The main questions it aims to answer are: * Does Delayed Cord Clamping at 120 seconds (DCC-120) or Delayed Cord Clamping at 30 seconds (DCC-30) after birth lead to better health outcomes? * Does DCC-120 seconds or DCC-30 seconds after birth lead to better neuromotor outcomes at 22-26 months of infant age (postnatal)? Participants will be asked to do the following: * Participate in either DCC-120 or DCC-30 at birth (randomized assignment). * Complete General Movements Assessment (GMA) at 3-4 months of infant age (postnatal), complete questionnaires / surveys at this time. * Complete questionnaires / surveys at 9-12 months of infant age (postnatal). * Complete Hammersmith Infant Neurological Examination (HINE), Developmental Assessment of Young Children 2 Edition (DAYC-2), and questionnaires / surveys at 22-26 months of infant age (postnatal). * Permit data collection from electronic medical records for both the mother and infant study participants. Investigators will compare DCC-120 vs. DCC-30 to see which approach is more beneficial to both the mother and baby with CHD.
Study identification
- NCT ID
- NCT06153459
- Recruitment status
- Recruiting
- Study type
- Interventional
- Phase
- Not applicable
- Enrollment
- 500 participants
Conditions and interventions
Conditions
Interventions
- Umbilical Cord Clamping at ~30 seconds Procedure
- Umbilical Cord Clamping at ~120 seconds Procedure
- Umbilical Cord Milking Procedure
Procedure
Eligibility (public fields only)
- Age range
- 37 Weeks to 42 Weeks
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 18, 2023
- Primary completion
- Sep 30, 2028
- Completion
- Nov 30, 2030
- Last update posted
- Aug 11, 2026
2023 – 2030
United States locations
- U.S. sites
- 18
- U.S. states
- 13
- U.S. cities
- 18
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Children's of Alabama | Birmingham | Alabama | 35233 | Recruiting |
| Cedars-Sinai Medical Center | Los Angeles | California | 90048 | Recruiting |
| Children's Hospital of Orange County | Orange | California | 92868 | Not yet recruiting |
| Lucile Packard Children's Hospital Stanford | Palo Alto | California | 94304 | Not yet recruiting |
| Sharp Mary Birch Hospital for Woman and Newborns | San Diego | California | 92123 | Recruiting |
| UF Health Shands Children's Hospital | Gainesville | Florida | 32608 | Recruiting |
| Johns Hopkins Children's Center | Baltimore | Maryland | 21287 | Recruiting |
| Children's of Mississippi | Jackson | Mississippi | 39216 | Recruiting |
| The Children's Mercy Hospital | Kansas City | Missouri | 64108 | Recruiting |
| SSM Health Cardinal Glennon Children's Hospital | St Louis | Missouri | 63104 | Recruiting |
| Duke Children's Hospital & Health Center | Durham | North Carolina | 27705 | Recruiting |
| Nationwide Children's Hospital | Columbus | Ohio | 43205 | Recruiting |
| Children's Hospital of Philadelphia | Philadelphia | Pennsylvania | 19104 | Recruiting |
| Medical University of South Carolina | Columbia | South Carolina | 29209 | Recruiting |
| Monroe Carell Jr. Children's Hospital at Vanderbilt | Nashville | Tennessee | 37232 | Recruiting |
| Texas Children's Hospital | Houston | Texas | 77030 | Recruiting |
| University of Texas Health Science Center at San Antonio | San Antonio | Texas | 78229 | Recruiting |
| Primary Children's Hospital | Salt Lake City | Utah | 84113 | Recruiting |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 3 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06153459, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 11, 2026 · Synced Sep 2, 2026
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Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06153459 live on ClinicalTrials.gov.