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Terminated Phase 2 Interventional Results available

Efficacy and Safety of MK-6194 in Adult Participants With Systemic Lupus Erythematosus (MK-6194-006)

ClinicalTrials.gov ID: NCT06161116

Public ClinicalTrials.gov record NCT06161116. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.

ClinicalTrials.gov public records Last synced Sep 29, 2026, 12:54 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Official title

A Phase 2a, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of MK-6194 in Adult Participants With Systemic Lupus Erythematosus

Brief summary

Reproduced verbatim from the official ClinicalTrials.gov record. Not medical advice.

The purpose of this study is to evaluate the efficacy and safety of MK-6194 in adult participants with systemic lupus erythematosus.

Study identification

NCT ID
NCT06161116
Recruitment status
Terminated
Study type
Interventional
Phase
Phase 2
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Enrollment
149 participants

Conditions and interventions

Interventions

Biological

Eligibility (public fields only)

Age range
18 Years to 75 Years
Sex
All
Healthy volunteers
Healthy volunteers not accepted

This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.

Study timeline

Start date
Dec 26, 2023
Primary completion
Jul 29, 2025
Completion
Jul 29, 2025
Last update posted
Aug 9, 2026

2023 – 2025

United States locations

U.S. sites
19
U.S. states
10
U.S. cities
18
Facility City State ZIP Site status
Medvin Clinical Research - Metyas ( Site 0128) Covina California 91722 —
UCSD - Altman Clinical and Translational Research Institute (ACTRI)-Center for Innovative Therapy ( Site 0110) La Jolla California 92037 —
Arthritis & Osteoporosis Medical Center - La Palma ( Site 0108) La Palma California 90623 —
Medvin Clinical Research - Tujunga ( Site 0127) Tujunga California 91042 —
Denver Arthritis Clinic ( Site 0102) Denver Colorado 80230 —
Clinical Research of West Florida, Inc. (Clearwater) ( Site 0111) Clearwater Florida 33765 —
IRIS Research and Development, LLC-Research ( Site 0117) Plantation Florida 33324 —
Clinical Research of West Florida, Inc ( Site 0124) Tampa Florida 33606 —
Morehouse School of Medicine ( Site 0146) Atlanta Georgia 30310 —
Accurate Clinical Research, Inc ( Site 0135) Lake Charles Louisiana 70605 —
AA Medical Research Center ( Site 0136) Grand Blanc Michigan 48439 —
Javara - Tryon Medical Partners ( Site 0121) Charlotte North Carolina 28210 —
DJL Clinical Research, PLLC ( Site 0103) Charlotte North Carolina 28211 —
University of Oklahoma Health Science Center ( Site 0130) Oklahoma City Oklahoma 73104 —
Shelby Research, LLC ( Site 0142) Memphis Tennessee 38119 —
Accurate Clinical Management, LLC. ( Site 0134) Baytown Texas 77521 —
Epic Medical Research ( Site 0113) DeSoto Texas 75115 —
Accurate Clinical Research, Inc. ( Site 0133) Houston Texas 77089 —
SouthWest Rheumatology Research, LLC ( Site 0115) Mesquite Texas 75150 —

Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.

Non-U.S. locations

This page focuses on the U.S. directory. The official record also lists 108 non-U.S. sites.

About this trial record page

What this page shows
Public field values for ClinicalTrials.gov record NCT06161116, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
What this page does not do
No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
Where the data comes from
Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
Last refresh
Last update posted Aug 9, 2026 · Synced Sep 29, 2026

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Open the official record

The complete protocol, eligibility criteria, and contact information for NCT06161116 live on ClinicalTrials.gov.

View official ClinicalTrials.gov record →