A Study to Investigate the Efficacy and Safety of Verekitug (UPB-101) in Participants With Chronic Rhinosinusitis With Nasal Polyps
Public ClinicalTrials.gov record NCT06164704. Field values are reproduced from the official study page; the official ClinicalTrials.gov record remains the source of truth for eligibility, enrollment, and contact information.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Official title
A Phase 2, Randomized, Double-blind, Placebo-controlled, Multi-center Study to Assess the Efficacy and Safety of Verekitug (UPB-101) in Participants With Chronic Rhinosinusitis With Nasal Polyps on a Background of Nasal Corticosteroids (VIBRANT)
Study identification
- NCT ID
- NCT06164704
- Recruitment status
- Completed
- Study type
- Interventional
- Phase
- Phase 2
- Lead sponsor
- Upstream Bio Inc.
- Industry
- Enrollment
- 81 participants
Conditions and interventions
Conditions
Interventions
- Verekitug (UPB-101) Drug
- Placebo Drug
Drug
Eligibility (public fields only)
- Age range
- 18 Years to 85 Years
- Sex
- All
- Healthy volunteers
- Healthy volunteers not accepted
This page does not interpret eligibility. Detailed inclusion and exclusion criteria are on the official ClinicalTrials.gov record.
Study timeline
- Start date
- Dec 17, 2023
- Primary completion
- Jul 6, 2025
- Completion
- Jul 21, 2025
- Last update posted
- Aug 14, 2025
2023 – 2025
United States locations
- U.S. sites
- 27
- U.S. states
- 16
- U.S. cities
- 25
| Facility | City | State | ZIP | Site status |
|---|---|---|---|---|
| Sensa Health LA (Sensa Health Clinical Research) | Los Angeles | California | 90006 | — |
| NewportNativeMD, Inc. | Newport Beach | California | 92782 | — |
| DaVinci, Research LLC | Roseville | California | 95661 | — |
| Senta Clinic | San Diego | California | 92108 | — |
| University of Missouri | Columbus | Colorado | 65212 | — |
| Western States Clinical Research, Inc. | Wheat Ridge | Colorado | 80033 | — |
| Alfa Medical Research | Hollywood | Florida | 33024 | — |
| Novaceut Clinical Research | Miami | Florida | 33013 | — |
| Well Pharma Medical Research Corp. | Miami | Florida | 33173 | — |
| IMIC Inc. | Miami | Florida | 33176 | — |
| University of South Florida | Tampa | Florida | 33613-3923 | — |
| Treasure Valley Medical Research | Boise | Idaho | 83706 | — |
| The University of Chicago | Chicago | Illinois | 60637 | — |
| Advanced ENT and Allergy | Louisville | Kentucky | 40220 | — |
| Chesapeake Clinical Research, Inc. | White Marsh | Maryland | 21162 | — |
| Brigham and Women's Hospital | Boston | Massachusetts | 02115 | — |
| Northwell Health/Division of Allergy and Immunology | Great Neck | New York | 11021 | — |
| University of Cincinnati Medical Center | Cincinnati | Ohio | 45106 | — |
| Allergy, Asthma & Clinical Research Center | Oklahoma City | Oklahoma | 73120-9389 | — |
| Spartanburg /Greer ENT & Allergy | Spartanburg | South Carolina | 29303 | — |
| Orion Clinical Research | Austin | Texas | 78759 | — |
| Alina Clinical Trials, LLC. | Dallas | Texas | 75209 | — |
| Ears Nose and Throat Associates of Texas | McKinney | Texas | 75070 | — |
| Alamo Ent Associates | San Antonio | Texas | 78258 | — |
| Eastern Virginia Medical School | Norfolk | Virginia | 23507-1904 | — |
| Bellingham Asthma, Allergy & Immunology Clinic | Bellingham | Washington | 98225 | — |
| Allergy, Asthma and Sinus Center, S.C. | Greenfield | Wisconsin | 53228 | — |
Site contact phone numbers, emails, and investigator names are intentionally not displayed here. Open the official ClinicalTrials.gov record for site contact information.
Non-U.S. locations
This page focuses on the U.S. directory. The official record also lists 14 non-U.S. sites.
About this trial record page
- What this page shows
- Public field values for ClinicalTrials.gov record NCT06164704, including study identification, conditions, interventions, eligibility (age, sex, healthy volunteer), timeline, and U.S. site list.
- What this page does not do
- No medical advice, eligibility judgments, treatment recommendations, study quality scoring, or AI-generated medical summaries. No site contact phone numbers, emails, or investigator names.
- Where the data comes from
- Sourced from the official ClinicalTrials.gov public API. The official record is the source of truth.
- Last refresh
- Last update posted Aug 14, 2025 · Synced Jul 21, 2026
Related: full search, browse by condition, browse by drug or therapy, browse by sponsor, browse by U.S. city.
Open the official record
The complete protocol, eligibility criteria, and contact information for NCT06164704 live on ClinicalTrials.gov.